Patents by Inventor Helen McShane

Helen McShane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions for immunizing against mycobacterium
    Patent number: 7850979
    Abstract: A method for generating a T cell immune response in a host involving administering a vectored vaccine comprising a non-replicating or replication impaired viral vector expressing the translation product of a mycobacterial antigen 85A gene. Vectored vaccines and uses thereof are also provided. Also provided is a method of inducing a CD8 and a CD4 memory T cell response against an antigen using an adenovirus vector expressing an antigen or an immunogenic fragment thereof.
    Type: Grant
    Filed: January 5, 2006
    Date of Patent: December 14, 2010
    Assignee: Isis Innovation Limited
    Inventors: Helen McShane, Ansar A. Pathan, Adrian Hill, Sarah C. Gilbert
  • Compositions for Immunizing Against Mycobacterium
    Publication number: 20080226678
    Abstract: A method for generating a T cell immune response in a host involving administering a vectored vaccine comprising a non-replicating or replication impaired viral vector expressing the translation product of a mycobacterial antigen 85A gene. Vectored vaccines and uses thereof are also provided. Also provided is a method of inducing a CD8 and a CD4 memory T cell response against an antigen using an adenovirus vector expressing an antigen or an immunogenic fragment thereof.
    Type: Application
    Filed: January 5, 2006
    Publication date: September 18, 2008
    Applicant: ISIS INNOVATION LIMITED
    Inventors: Helen McShane, Ansar A. Pathan, Adrian Hill, Sarah C. Gilbert
  • Vacination method
    Publication number: 20040018177
    Abstract: There is provided a method of inducing a CD4+ T-cell response against a target antigen, by administering a composition a source of one or more CD4+ epitopes is a non-replicating or replication impaired recombinant poxvirus vector.
    Type: Application
    Filed: July 15, 2003
    Publication date: January 29, 2004
    Inventors: Adrian V.S. Hill, Helen McShane, Sarah Gilbert, Joerg Schneider
  • Vaccination method
    Publication number: 20030138454
    Abstract: New methods and reagents for vaccination are described which generate a CD8 T cell immune response against malarial and other antigens such as viral and tumour antigens. Novel vaccination regimes are described which employ a priming composition and a boosting composition, the boosting composition comprising a non-replicating or replication-impaired pox virus vector carrying at least one CD8 T cell epitope which is also present in the priming composition. There is also provided a method of inducing a CD4+ T-cell response against a target antigen, by administering a composition comprising a source of one or more CD4+ T cell epitopes of the target antigen wherein the source of CD4+ epitopes is a non-replicating or replication impaired recombinant poxvirus vector. A method of inducing a combined CD4+ and CD8+ T cell response against a target antigen is also described herein.
    Type: Application
    Filed: February 19, 2002
    Publication date: July 24, 2003
    Applicant: Oxxon Pharmaccines, Ltd.
    Inventors: Adrian V. S. Hill, Helen McShane, Sarah C. Gilbert, William Reece, Joerg Schneider