Patents by Inventor Helen S. PENTIKIS
Helen S. PENTIKIS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11684607Abstract: Embodiments are directed to a secnidazole formulations and the use of a secnidazole formulation for the treatment of bacterial vaginosis (BV).Type: GrantFiled: May 31, 2021Date of Patent: June 27, 2023Assignee: LUPIN, INC.Inventors: Helen S. Pentikis, David Palling, Carol J. Braun
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Patent number: 11602522Abstract: Method of treating sexually transmitted infection in a subject in need thereof involving administering to the subject a therapeutically effective amount of secnidazole in a microgranule formulation, wherein the microgranule formulation comprises a plurality of microgranules having a volume-weighted particle size distribution within a microgranule population, wherein the volume-weighted particle size distribution as measured from a representative sample of the microgranule population comprises (a) 10% of the microgranule population having a volume-weighted particle size about no less than 470 micrometers; (b) 50% of the microgranule population having a volume-weighted particle size between about no less than 640 micrometers and about no more than 810 micrometers; (c) 90% of the microgranule population having a volume-weighted particle size about no more than 1170 micrometers; or (d) a combination thereof, which can include some or all of (a) through (c) above.Type: GrantFiled: May 7, 2021Date of Patent: March 14, 2023Assignee: LUPIN INC.Inventors: Helen S. Pentikis, David Palling, Carol J. Braun, Richard Holl
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Patent number: 11324721Abstract: Embodiments are directed to secnidazole formulations and the use of a secnidazole formulation for the treatment of trichomoniasis in a subject in need thereof.Type: GrantFiled: June 2, 2020Date of Patent: May 10, 2022Assignee: Lupin Inc.Inventors: Helen S. Pentikis, David Palling, Carol J. Braun
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Publication number: 20220087978Abstract: Method of treating or preventing trichomoniasis or T. vaginalis infection in a subject in need thereof, the method involving administering to the subject a therapeutically effective amount of secnidazole or a pharmaceutically acceptable salt in a microgranule formulation, wherein the microgranule formulation comprises a plurality of microgranules. The subject can also have bacterial vaginosis, is HIV-positive, and/or is suffering with metronidazole-resistant trichomoniasis and/or tinidazole-resistant trichomoniasis. The subject can also be a sexual partner of a person with trichomoniasis. The microgranule formulation can also be administered with paromomycin, tinidazole, metronidazole, boric acid or a combination thereof. Pharmaceutical compositions and uses for treating or preventing trichomoniasis or T. vaginalis infection in a subject in need thereof are also contemplated herein.Type: ApplicationFiled: September 22, 2020Publication date: March 24, 2022Applicant: LUPIN INC.Inventors: Helen S. PENTIKIS, David PALLING, Carol J. BRAUN, Richard HOLL, Gregory KAUFMAN
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Publication number: 20210283106Abstract: Embodiments are directed to a secnidazole formulations and the use of a secnidazole formulation for the treatment of bacterial vaginosis (BV).Type: ApplicationFiled: May 31, 2021Publication date: September 16, 2021Applicant: Lupin Inc.Inventors: Helen S. PENTIKIS, David PALLING, Carol J. BRAUN
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Publication number: 20210260038Abstract: Method of treating a sexually transmitted infection in a subject in need thereof involving administering to the subject a therapeutically effective amount of secnidazole in a microgranule formulation, wherein the microgranule formulation comprises a plurality of microgranules having a volume-weighted particle size distribution within a microgranule population, wherein the volume-weighted particle size distribution as measured from a representative sample of the microgranule population comprises (a) 10% of the microgranule population having a volume-weighted particle size about no less than 470 micrometers; (b) 50% of the microgranule population having a volume-weighted particle size between about no less than 640 micrometers and about no more than 810 micrometers; (c) 90% of the microgranule population having a volume-weighted particle size about no more than 1170 micrometers; or (d) a combination thereof, which can include some or all of (a) through (c) above.Type: ApplicationFiled: May 7, 2021Publication date: August 26, 2021Applicant: LUPIN INC.Inventors: Helen S. PENTIKIS, David PALLING, Carol J. BRAUN, Richard HOLL
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Patent number: 11020377Abstract: Embodiments are directed to a secnidazole formulations and the use of a secnidazole formulation for the treatment of bacterial vaginosis (BV).Type: GrantFiled: September 27, 2019Date of Patent: June 1, 2021Assignee: LUPIN INC.Inventors: Helen S. Pentikis, David Palling, Carol J. Braun
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Patent number: 11000508Abstract: Method of treating trichomoniasis in a subject in need thereof involving administering to the subject a therapeutically effective amount of secnidazole in a microgranule formulation, wherein the microgranule formulation comprises a plurality of microgranules having a volume-weighted particle size distribution within a microgranule population, wherein the volume-weighted particle size distribution as measured from a representative sample of the microgranule population comprises (a) at least 10% of the microgranule population having a volume-weighted particle size about no less than 470 micrometers; or (b) 50% of the microgranule population having a volume-weighted particle size between about no less than 640 micrometers and about no more than 810 micrometers; or (c) 90% of the microgranule population having a volume-weighted particle size about no more than 1170 micrometers; or (d) a combination thereof, which can include some or all of (a) through (c) above.Type: GrantFiled: June 15, 2020Date of Patent: May 11, 2021Assignee: LUPIN INC.Inventors: Helen S. Pentikis, David Palling, Carol J. Braun, Richard Holl
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Patent number: 11000507Abstract: Method of treating bacterial vaginosis in a subject in need thereof involving administering to the subject a therapeutically effective amount of secnidazole in a microgranule formulation, wherein the microgranule formulation comprises a plurality of microgranules having a volume-weighted particle size distribution within a microgranule population, wherein the volume-weighted particle size distribution as measured from a representative sample of the microgranule population comprises (a) at least 10% of the microgranule population having a volume-weighted particle size about no less than 470 micrometers; or (b) 50% of the microgranule population having a volume-weighted particle size between about no less than 640 micrometers and about no more than 810 micrometers; or (c) 90% of the microgranule population having a volume-weighted particle size about no more than 1170 micrometers; or (d) a combination thereof, which can include some or all of (a) through (c) above.Type: GrantFiled: March 12, 2020Date of Patent: May 11, 2021Assignee: LUPIN INC.Inventors: Helen S. Pentikis, David Palling, Carol J. Braun, Richard Holl
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Patent number: 10857133Abstract: Embodiments are directed to a secnidazole formulations and the use of a secnidazole formulation for the treatment of bacterial vaginosis (BV).Type: GrantFiled: September 27, 2019Date of Patent: December 8, 2020Assignee: LUPIN INC.Inventors: Helen S. Pentikis, David Palling, Carol J. Braun
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Patent number: 10849884Abstract: Embodiments are directed to a secnidazole formulations and the use of a secnidazole formulation for the treatment of bacterial vaginosis (BV).Type: GrantFiled: May 3, 2019Date of Patent: December 1, 2020Assignee: LUPIN INC.Inventors: Helen S. Pentikis, David Palling, Carol J. Braun
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Publication number: 20200306228Abstract: Method of treating trichomoniasis in a subject in need thereof involving administering to the subject a therapeutically effective amount of secnidazole in a microgranule formulation, wherein the microgranule formulation comprises a plurality of microgranules having a volume-weighted particle size distribution within a microgranule population, wherein the volume-weighted particle size distribution as measured from a representative sample of the microgranule population comprises (a) 10% of the microgranule population having a volume-weighted particle size about no less than 470 micrometers; (b) 50% of the microgranule population having a volume-weighted particle size between about no less than 640 micrometers and about no more than 810 micrometers; (c) 90% of the microgranule population having a volume-weighted particle size about no more than 1170 micrometers; or (d) a combination thereof, which can include some or all of (a) through (c) above.Type: ApplicationFiled: June 15, 2020Publication date: October 1, 2020Applicant: LUPIN INC.Inventors: Helen S. PENTIKIS, David PALLING, Carol J. BRAUN, Richard HOLL
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Publication number: 20200289470Abstract: Embodiments are directed to a secnidazole formulations and the use of a secnidazole formulation for the treatment of trichomoniasis in a subject in need thereof.Type: ApplicationFiled: June 2, 2020Publication date: September 17, 2020Applicant: LUPIN INC.Inventors: Helen S. PENTIKIS, David PALLING, Carol J. BRAUN
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Publication number: 20200206192Abstract: Method of treating bacterial vaginosis in a subject in need thereof involving administering to the subject a therapeutically effective amount of secnidazole in a microgranule formulation, wherein the microgranule formulation comprises a plurality of microgranules having a volume-weighted particle size distribution within a microgranule population, wherein the volume-weighted particle size distribution as measured from a representative sample of the microgranule population comprises (a) 10% of the microgranule population having a volume-weighted particle size about no less than 470 micrometers; (b) 50% of the microgranule population having a volume-weighted particle size between about no less than 640 micrometers and about no more than 810 micrometers; (c) 90% of the microgranule population having a volume-weighted particle size about no more than 1170 micrometers; or (d) a combination thereof, which can include some or all of (a) through (c) above.Type: ApplicationFiled: March 12, 2020Publication date: July 2, 2020Applicant: LUPIN INC.Inventors: Helen S. PENTIKIS, David PALLING, Carol J. BRAUN, Richard HOLL
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Patent number: 10682338Abstract: Method of treating bacterial vaginosis in a subject in need thereof involving administering to the subject a therapeutically effective amount of secnidazole in a microgranule formulation, wherein the microgranule formulation comprises a plurality of microgranules having a volume-weighted particle size distribution within a microgranule population, wherein the volume-weighted particle size distribution as measured from a representative sample of the microgranule population comprises (a) 10% of the microgranule population having a volume-weighted particle size about no less than 470 micrometers; (b) 50% of the microgranule population having a volume-weighted particle size between about no less than 640 micrometers and about no more than 810 micrometers; (c) 90% of the microgranule population having a volume-weighted particle size about no more than 1170 micrometers; or (d) a combination thereof, which can include some or all of (a) through (c) above.Type: GrantFiled: July 30, 2018Date of Patent: June 16, 2020Assignee: Lupin Inc.Inventors: Helen S. Pentikis, David Palling, Carol J. Braun, Richard Holl
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Publication number: 20200038372Abstract: Embodiments are directed to a secnidazole formulations and the use of a secnidazole formulation for the treatment of bacterial vaginosis (BV).Type: ApplicationFiled: September 27, 2019Publication date: February 6, 2020Applicant: SYMBIOMIX THERAPEUTICS, LLCInventors: Helen S. PENTIKIS, David PALLING, Carol J. BRAUN
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Publication number: 20200022958Abstract: Embodiments are directed to a secnidazole formulations and the use of a secnidazole formulation for the treatment of bacterial vaginosis (BV).Type: ApplicationFiled: September 27, 2019Publication date: January 23, 2020Applicant: SYMBIOMIX THERAPEUTICS, LLCInventors: Helen S. PENTIKIS, David PALLING, Carol J. BRAUN
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Publication number: 20190255020Abstract: Embodiments are directed to a secnidazole formulations and the use of a secnidazole formulation for the treatment of bacterial vaginosis (BV).Type: ApplicationFiled: May 3, 2019Publication date: August 22, 2019Applicant: SYMBIOMIX THERAPEUTICS, LLCInventors: Helen S. PENTIKIS, David PALLING, Carol J. BRAUN
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Patent number: 10335390Abstract: Embodiments are directed to a secnidazole formulations and the use of a secnidazole formulation for the treatment of bacterial vaginosis (BV).Type: GrantFiled: September 4, 2015Date of Patent: July 2, 2019Assignee: Symbiomix Therapeutics, LLCInventors: Helen S. Pentikis, David Palling, Carol J. Braun
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Publication number: 20180333391Abstract: Method of treating bacterial vaginosis in a subject in need thereof involving administering to the subject a therapeutically effective amount of secnidazole in a microgranule formulation, wherein the microgranule formulation comprises a plurality of microgranules having a volume-weighted particle size distribution within a microgranule population, wherein the volume-weighted particle size distribution as measured from a representative sample of the microgranule population comprises (a) 10% of the microgranule population having a volume-weighted particle size about no less than 470 micrometers; (b) 50% of the microgranule population having a volume-weighted particle size between about no less than 640 micrometers and about no more than 810 micrometers; (c) 90% of the microgranule population having a volume-weighted particle size about no more than 1170 micrometers; or (d) a combination thereof, which can include some or all of (a) through (c) above.Type: ApplicationFiled: July 30, 2018Publication date: November 22, 2018Applicant: SYMBIOMIX THERAPEUTICS, LLCInventors: Helen S. PENTIKIS, David PALLING, Carol J. BRAUN, Richard HOLL