Patents by Inventor Helen Xi Chen

Helen Xi Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds that inhibit human DNA ligases and methods of treating cancer
    Patent number: 9757375
    Abstract: Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into the reaction mechanisms of human DNA ligases, for example to identify the human DNA ligase involved in different DNA repair pathways. Screening methods for compounds that inhibit human DNA ligases.
    Type: Grant
    Filed: June 3, 2015
    Date of Patent: September 12, 2017
    Assignee: University of Maryland, Baltimore
    Inventors: Alan E. Tomkinson, Helen Xi Chen, Barbara Dziegielewska, Alexander D. Mackerell, Shijun Zhong, Gerald M. Wilson
  • COMPOUNDS THAT INHIBIT HUMAN DNA LIGASES AND METHODS OF TREATING CANCER
    Publication number: 20150313898
    Abstract: Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into the reaction mechanisms of human DNA ligases, for example to identify the human DNA ligase involved in different DNA repair pathways. Screening methods for compounds that inhibit human DNA ligases.
    Type: Application
    Filed: June 3, 2015
    Publication date: November 5, 2015
    Inventors: Alan E. Tomkinson, Helen Xi Chen, Barbara Dziegielewska, Alexander D. Mackerell, Shijun Zhong, Gerald M. Wilson
  • Compounds that inhibit human DNA ligases and methods of treating cancer
    Patent number: 9073896
    Abstract: Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into the reaction mechanisms of human DNA ligases, for example to identify the human DNA ligase involved in different DNA repair pathways. Screening methods for compounds that inhibit human DNA ligases.
    Type: Grant
    Filed: April 17, 2013
    Date of Patent: July 7, 2015
    Assignee: University of Maryland, Baltimore
    Inventors: Alan E. Tomkinson, Helen Xi Chen, Barbara Dziegielewska, Alexander D. Mackerell, Shijun Zhong, Gerald M. Wilson