Patents by Inventor Helen Yu
Helen Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250139116Abstract: Systems and methods provide an interface for accessing a data analysis workbook through which data is accessed and manipulated using a plurality of programming languages and application programming interfaces (APIs). Input data on which one or more data transformations are to be performed within the data analysis workbook is accessed, wherein the input data corresponds to a first object representation of a dataset, and wherein the one or more data transformations require the dataset to be a different, second object representation of the dataset. The second object representation of the dataset can be extracted from the first object representation of the dataset through a first language delegate that manages data associated with the first object representation. The one or more data transformations can be applied to the extracted second object representation of the dataset through a different, second language delegate that manages data associated with the second object representation.Type: ApplicationFiled: December 31, 2024Publication date: May 1, 2025Inventors: Jeremy LIU, David Vogelbacher, Eoin Morgan, Helen Yu
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Patent number: 12189646Abstract: Systems and methods are provided for providing an interface for accessing a data analysis workbook through which data can be accessed and manipulated using a plurality of programming languages and application programming interfaces (APIs). Input data on which one or more data transformations are to be performed within the data analysis workbook can be accessed, wherein the input data corresponds to a first object representation of a dataset, and wherein the one or more data transformations require the dataset to be a different, second object representation of the dataset. The second object representation of the dataset can be extracted from the first object representation of the dataset through a first language delegate that manages data associated with the first object representation. The one or more data transformations can be applied to the extracted second object representation of the dataset through a different, second language delegate that manages data associated with the second object representation.Type: GrantFiled: May 17, 2022Date of Patent: January 7, 2025Assignee: Palantir Technologies Inc.Inventors: Jeremy Liu, David Vogelbacher, Eoin Morgan, Helen Yu
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Publication number: 20240354326Abstract: A system for enabling granular access control over ontology data and related methods are disclosed. The system is programmed to receive data source updates from data sources having respective sets of permissions for access control, transform the data source updates to changes to an ontology, and control access to the ontology based on the sets of permissions. The system is further programmed to receive a specification of one or more rules referencing attributes of user accounts or properties of ontology entities and corresponding one or more lists of permissions. The system is programmed to then enforce a security policy based on the specification to further control access to the ontology.Type: ApplicationFiled: April 22, 2024Publication date: October 24, 2024Inventors: JAMES BAKER, XAVIER FALCO, SAMUEL FLAVIO BARROSO SOUZA, HELEN YU, AMR AL MALLAH, YIXUN XU, ARSENY BOGOMOLOV
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Publication number: 20240354325Abstract: A system for indexing changes to an ontology into multiple databases and related methods are disclosed. The system is programmed to receive original data from data sources, transform the original data to ontology data, represent the ontology data in multiple forms respectively in the multiple databases, and process requests to access the ontology data from user accounts using the multiple databases. The system is programmed to subsequently merge changes to the ontology data based on updates from the data sources and edits from user accounts, create index data for the merged changes, and transmit the index data to the multiple databases.Type: ApplicationFiled: April 22, 2024Publication date: October 24, 2024Inventors: JAMES BAKER, XAVIER FALCO, SAMUEL FLAVIO BARROSO SOUZA, HELEN YU, AMR AL MALLAH, YIXUN XU, ARSENY BOGOMOLOV
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Publication number: 20240354295Abstract: A system for resolving conflicts between data source updates and user edits to an ontology before applying the resulting changes to the ontology and related methods are disclosed. The system is programmed to receive data source updates from data sources and transform the data source updates to updates to ontology data. The system is also programmed to receive edits to ontology data from user accounts. The system is programmed to review these updates or edits to the ontology and resolve conflicts according to a predetermined strategy, such as prioritizing a user edit over a data source update. The resulting changes are incorporated to one or more databases where representations of the ontology data are stored.Type: ApplicationFiled: April 22, 2024Publication date: October 24, 2024Inventors: JAMES BAKER, XAVIER FALCO, SAMUEL FLAVIO BARROSO SOUZA, HELEN YU, AMR AL MALLAH, YIXUN XU, ARSENY BOGOMOLOV
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Patent number: 11897862Abstract: The present disclosure relates generally to compounds that bind to and act as degraders of an IKAROS Family Zinc Finger (IKZF) protein, such as IKZF2 (Helios) and/or IKZF4 (Eos). The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding and degradation of an IKZF protein, such as IKZF2 and/or IKZF4, including cancer.Type: GrantFiled: April 7, 2023Date of Patent: February 13, 2024Assignee: Gilead Sciences, Inc.Inventors: Gayatri Balan, Peter A. Blomgren, Chen Chen, Julian A. Codelli, Zhimin Du, Musong Kim, Dorothée Saddier Axe, Gregg M. Schwarzwalder, Rhiannon Thomas-Tran, Michael T. Tudesco, Chandrasekar Venkataramani, William J. Watkins, Brian M. Weist, Suet C. Yeung, Helen Yu
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Publication number: 20240034774Abstract: Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.Type: ApplicationFiled: August 4, 2023Publication date: February 1, 2024Inventors: Mini Balakrishnan, Brian A. Carr, Magdeleine S. Hung, Manu Kanwar, Craig S. Pace, Doug Rehder, Matthew Robert Schenauer, Loredana Serafini, Heather Theresa Stephenson, Nathan D. Thomsen, Helen Yu, Xue Zhang
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Publication number: 20230373950Abstract: The present disclosure relates generally to compounds that bind to and act as degraders of an IKAROS Family Zinc Finger (IKZF) protein, such as IKZF2 (Helios) and/or IKZF4 (Eos). The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding and degradation of an IKZF protein, such as IKZF2 and/or IKZF4, including cancer.Type: ApplicationFiled: March 15, 2023Publication date: November 23, 2023Inventors: Gayatri Balan, Peter A. Blomgren, Chen Chen, Julian A. Codelli, Zhimin Du, Musong Kim, Dorothée Saddier Axe, Gregg M. Schwarzwalder, Rhiannon Thomas-Tran, Michael T. Tudesco, Chandrasekar Venkataramani, William J. Watkins, Brian M. Weist, Suet C. Yeung, Helen Yu
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Publication number: 20230317212Abstract: Systems and methods for generating ligand compound structures are provided. A trained computational framework can utilize an initial core ligand compound structure to generate a ligand compound structure by iteratively adding atomic structures. At each iterative step, the computational framework can select a location for adding an atomic structure and can further select which atomic structure is to be added the selected location.Type: ApplicationFiled: March 15, 2023Publication date: October 5, 2023Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Alexander S. Powers, Helen Yu, Patricia A. Suriana, Ron O. Dror
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Publication number: 20230295111Abstract: The present disclosure relates generally to compounds that bind to and act as degraders of an IKAROS Family Zinc Finger (IKZF) protein, such as IKZF2 (Helios) and/or IKZF4 (Eos). The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding and degradation of an IKZF protein, such as IKZF2 and/or IKZF4, including cancer.Type: ApplicationFiled: April 7, 2023Publication date: September 21, 2023Inventors: Gayatri Balan, Peter A. Blomgren, Chen Chen, Julian A. Codelli, Zhimin Du, Musong Kim, Dorothée Saddier Axe, Gregg M. Schwarzwalder, Rhiannon Thomas-Tran, Michael T. Tudesco, Chandrasekar Venkataramani, William J. Watkins, Brian M. Weist, Suet C. Yeung, Helen Yu
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Publication number: 20220277016Abstract: Systems and methods are provided for providing an interface for accessing a data analysis workbook through which data can be accessed and manipulated using a plurality of programming languages and application programming interfaces (APIs). Input data on which one or more data transformations are to be performed within the data analysis workbook can be accessed, wherein the input data corresponds to a first object representation of a dataset, and wherein the one or more data transformations require the dataset to be a different, second object representation of the dataset. The second object representation of the dataset can be extracted from the first object representation of the dataset through a first language delegate that manages data associated with the first object representation. The one or more data transformations can be applied to the extracted second object representation of the dataset through a different, second language delegate that manages data associated with the second object representation.Type: ApplicationFiled: May 17, 2022Publication date: September 1, 2022Inventors: Jeremy Liu, David Vogelbacher, Eoin Morgan, Helen Yu
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Patent number: 11334591Abstract: Systems and methods are provided for providing an interface for accessing a data analysis workbook through which data can be accessed and manipulated using a plurality of programming languages and application programming interfaces (APIs). Input data on which one or more data transformations are to be performed within the data analysis workbook can be accessed, wherein the input data corresponds to a first object representation of a dataset, and wherein the one or more data transformations require the dataset to be a different, second object representation of the dataset. The second object representation of the dataset can be extracted from the first object representation of the dataset through a first language delegate that manages data associated with the first object representation. The one or more data transformations can be applied to the extracted second object representation of the dataset through a different, second language delegate that manages data associated with the second object representation.Type: GrantFiled: October 11, 2019Date of Patent: May 17, 2022Assignee: Palantir Technologies Inc.Inventors: Jeremy Liu, David Vogelbacher, Eoin Morgan, Helen Yu
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Publication number: 20220089698Abstract: Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.Type: ApplicationFiled: October 7, 2021Publication date: March 24, 2022Inventors: Mini Balakrishnan, Brian A. Carr, Magdeleine S. Hung, Manu Kanwar, Craig S. Pace, Doug Rehder, Matthew Robert Schenauer, Loredana Serafini, Heather Theresa Stephenson, Nathan D. Thomsen, Helen Yu, Xue Zhang
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Patent number: 11168130Abstract: Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.Type: GrantFiled: July 2, 2019Date of Patent: November 9, 2021Assignee: GILEAD SCIENCES, INC.Inventors: Mini Balakrishnan, Brian A. Carr, Craig S. Pace, Doug Rehder, Matthew Robert Schenauer, Loredana Serafini, Heather Theresa Stephenson, Nathan D. Thomsen, Helen Yu, Xue Zhang
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Publication number: 20210049182Abstract: Systems and methods are provided for providing an interface for accessing a data analysis workbook through which data can be accessed and manipulated using a plurality of programming languages and application programming interfaces (APIs). Input data on which one or more data transformations are to be performed within the data analysis workbook can be accessed, wherein the input data corresponds to a first object representation of a dataset, and wherein the one or more data transformations require the dataset to be a different, second object representation of the dataset. The second object representation of the dataset can be extracted from the first object representation of the dataset through a first language delegate that manages data associated with the first object representation. The one or more data transformations can be applied to the extracted second object representation of the dataset through a different, second language delegate that manages data associated with the second object representation.Type: ApplicationFiled: October 11, 2019Publication date: February 18, 2021Inventors: Jeremy Liu, David Vogelbacher, Eoin Morgan, Helen Yu
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Publication number: 20200223907Abstract: Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.Type: ApplicationFiled: July 2, 2019Publication date: July 16, 2020Applicant: Gilead Sciences, Inc.Inventors: Mini Balakrishnan, Brian A. Carr, Magdeleine S. Hung, Manu Kanwar, Craig S. Pace, Doug Rehder, Matthew Robert Schenauer, Loredana Serafini, Heather Theresa Stephenson, Nathan D. Thomsen, Helen Yu, Xue Zhang
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Publication number: 20190266153Abstract: Techniques related to searches of highly structured data are described. A body of data may be represented by an object-centric data model. For a search of the body of data, an indication of a particular search template to use may be received. The particular search template may specify one or more hierarchical object types that are within a scope of the search. The one or more hierarchical object types may be defined in the object-centric data model. The particular search template may specify at least one search field. A user interface may be generated based on the particular search template. The user interface may include the at least one search field.Type: ApplicationFiled: May 10, 2019Publication date: August 29, 2019Inventors: KEVIN ZHANG, DAVID PHILIPSON, ARJUN NAYINI, HELEN Yu, ZENNARD SUN, ANTOINE LLORCA
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Patent number: 10296617Abstract: Techniques related to searches of highly structured data are described. A body of data may be represented by an object-centric data model. For a search of the body of data, an indication of a particular search template to use may be received. The particular search template may specify one or more hierarchical object types that are within a scope of the search. The one or more hierarchical object types may be defined in the object-centric data model. The particular search template may specify at least one search field. A user interface may be generated based on the particular search template. The user interface may include the at least one search field.Type: GrantFiled: October 5, 2015Date of Patent: May 21, 2019Assignee: Palantir Technologies Inc.Inventors: Kevin Zhang, David Philipson, Arjun Nayini, Helen Yu, Zennard Sun, Antoine Llorca
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Patent number: 10059697Abstract: Provided are compounds, compositions, combinations, kits, uses, and methods for treating HIV in a human being using such compounds or combinations with proteasome inhibitors.Type: GrantFiled: September 29, 2016Date of Patent: August 28, 2018Assignee: Gilead Sciences, Inc.Inventors: Tomas Cihlar, Michael Graupe, Yunfeng Eric Hu, Jeffrey Patrick Murry, Derek Dean Sloan, George Stepan, Helen Yu
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Publication number: 20170114048Abstract: Provided are compounds, compositions, combinations, kits, uses, and methods for treating HIV in a human being using such compounds or combinations with proteasome inhibitors.Type: ApplicationFiled: September 29, 2016Publication date: April 27, 2017Inventors: Tomas Cihlar, Michael Graupe, Yunfeng Eric Hu, Jeffrey Patrick Murry, Derek Dean Sloan, George Stepan, Helen Yu