Patents by Inventor Helena Corominola Ocana

Helena Corominola Ocana has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical Compositions for the Treatment of Neurodegenerative Disorders
    Publication number: 20080206356
    Abstract: Pharmaceutical compositions comprising an effective amount of a tungsten (VI) compound, preferably of a tungstate salt, and more preferably of sodium tungstate (Na2WO4), are useful for the prophylactic and/or therapeutical treatment of neurodegenerative disorders in a mammal, including a human, in particular, for the prophylactic and/or therapeutical treatment of Alzheimer's disease or schizophrenia. The effect of sodium tungstate dihydrate on the phosphorylation of tau in a model of rat insulin resistance and in a model of type-1 diabetes has been assessed. The therapeutic treatment of tauopathies that derives from this invention involves several advantages: it targets a GSK3; specificity since it reduces the abnormal hyperphosphorylation of a neural specific protein, tau, efficacy, lack of toxicity, and low price.
    Type: Application
    Filed: July 28, 2006
    Publication date: August 28, 2008
    Applicants: UNIVERSIDAD DE BARCELONA, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
    Inventors: Joan Josep Guinovart Cirera, Jesus Avila De Grado, Jorge Dominguez Reyes, Ramon Gomis De Barbara, Alberto Gomez Ramos, Delia Zafra Lopez, Helena Corominola Ocana