Patents by Inventor Helena DE ANDRADE

Helena DE ANDRADE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR IDENTIFYING HIGH-AFFINITY COMPLEXES MADE OF TWO LIGANDS AND ONE RECEPTOR, DEVICE FOR IMPLEMENTING THE METHOD AND SELF-ASSEMBLING CHEMICAL LIBRARY FOR USE IN THE METHOD
    Publication number: 20220298552
    Abstract: The present invention relates to a method for the sensitive identification of high-affinity complexes made of two ligands (2, 3, 4, 5, 6, 7) and one receptor (1). A large number of different ligands (2, 3, 4, 5, 6, 7) of a chemical library are hereby contacted with at least one receptor (1) in a solution. The ligands of the library have a single-strand DNA (8, 9) or RNA with a base length of 2 to 10 bases or alternatively more than 10 bases. In addition, the solution is incubated for a specific period of time and complexes made of two ligands (2, 3, 4, 5, 6, 7) and one receptor (1) are identified.
    Type: Application
    Filed: June 7, 2022
    Publication date: September 22, 2022
    Applicant: DYNABIND GMBH
    Inventors: Francesco REDDAVIDE, Helena DE ANDRADE, Weilin LIN, Yixin ZHANG
  • Method for identifying high-affinity complexes made of two ligands and one receptor, device for implementing the method and self-assembling chemical library for use in the method
    Patent number: 11365439
    Abstract: The present invention relates to a method for the sensitive identification of high-affinity complexes made of two ligands (2, 3, 4, 5, 6, 7) and one receptor (1). A large number of different ligands (2, 3, 4, 5, 6, 7) of a chemical library are hereby contacted with at least one receptor (1) in a solution. The ligands of the library have a single-strand DNA (8, 9) or RNA with a base length of 2 to 10 bases or alternatively more than 10 bases. In addition, the solution is incubated for a specific period of time and complexes made of two ligands (2, 3, 4, 5, 6, 7) and one receptor (1) are identified.
    Type: Grant
    Filed: July 10, 2015
    Date of Patent: June 21, 2022
    Assignee: DYNABIND GMBH
    Inventors: Francesco Reddavide, Helena De Andrade, Weilin Lin, Yixin Zhang
  • METHOD FOR IDENTIFYING HIGH-AFFINITY COMPLEXES MADE OF TWO LIGANDS AND ONE RECEPTOR, DEVICE FOR IMPLEMENTING THE METHOD AND SELF-ASSEMBLING CHEMICAL LIBRARY FOR USE IN THE METHOD
    Publication number: 20170198336
    Abstract: The present invention relates to a method for the sensitive identification of high-affinity complexes made of two ligands (2, 3, 4, 5, 6, 7) and one receptor (1). A large number of different ligands (2, 3, 4, 5, 6, 7) of a chemical library are hereby contacted with at least one receptor (1) in a solution. The ligands of the library have a single-strand DNA (8, 9) or RNA with a base length of 2 to 10 bases or alternatively more than 10 bases. In addition, the solution is incubated for a specific period of time and complexes made of two ligands (2, 3, 4, 5, 6, 7) and one receptor (1) are identified.
    Type: Application
    Filed: July 10, 2015
    Publication date: July 13, 2017
    Applicant: TECHNISCHE UNIVERSITAET DRESDEN
    Inventors: Francesco REDDAVIDE, Helena DE ANDRADE, Weilin LIN, Yixin ZHANG