Patents by Inventor Helena FLORINDO

Helena FLORINDO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATORS OF PD-L1/PD-1 INTERACTION AND USES THEREOF
    Publication number: 20230390287
    Abstract: Compounds (small molecules) capable of interfering with an interaction between PD-1 and PD-L1, and thereby are usable in treating cancer and/or in increasing T-cell function and/or in treating a medical condition associate with PD1, PD-L1 and/or T-cell function on cells, pharmaceutical compositions and kits comprising same and uses thereof, are provided.
    Type: Application
    Filed: August 18, 2023
    Publication date: December 7, 2023
    Applicant: Ramot at Tel-Aviv University Ltd.
    Inventors: Ronit SATCHI-FAINARO, Helena FLORINDO, Rita GUEDES, Rita ACÚRCIO
  • POLYMERIC NANOVACCINES AND USES THEREOF
    Publication number: 20220111029
    Abstract: A polymeric nanoparticle is disclosed which comprises: (i) at least one disease-associated antigen which is capable of producing a T-cell response, wherein the disease-associated antigen is encapsulated in the nanoparticle; (ii) at least one adjuvant; and (iii) a dendritic cell targeting moiety which is attached to the outer surface of the nanoparticle. Use of the nanoparticle for treating diseases associated with abnormal cell growth or an infection is also disclosed.
    Type: Application
    Filed: December 27, 2019
    Publication date: April 14, 2022
    Applicant: Ramot at Tel-Aviv University Ltd.
    Inventors: Ronit SATCHI-FAINARO, Helena FLORINDO, Joao CONNIOT, Anna SCOMPARIN