Patents by Inventor Helena Ljusberg-Wahren
Helena Ljusberg-Wahren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20130267585Abstract: A pharmaceutical composition comprising a pharmaceutically effective amount of a pharmaceutically active substance and a pharmaceutically acceptable carrier including a cationic excipient, wherein said cationic excipient is a labile ester of betaine and a lipophilic alcohol having at least one primary hydroxyl group. Also, the use of a labile ester of betaine and a lipophilic alcohol having at least a primary hydroxyl group as a cationic excipient in a carrier for a pharmaceutical composition comprising a pharmaceutically active substance.Type: ApplicationFiled: May 15, 2013Publication date: October 10, 2013Applicant: CAMURUS ABInventors: HELENA LJUSBERG-WAHREN, DAN LUNDBERG, KRISTER HOLMBERG
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Publication number: 20070031485Abstract: The invention relates to a pharmaceutical composition comprising a pharmaceutically effective amount of a pharmaceutically active substance and a pharmaceutically acceptable carrier comprising a cationic excipient, wherein said cationic excipient is a labile ester of betaine and a lipophilic alcohol having at least one primary hydroxyl group. The invention also relates to the use of a labile ester of betaine and a lipophilic alcohol having at least a primary hydroxyl group as a cationic excipient in a carrier for a pharmaceutical composition comprising a pharmaceutically active substance.Type: ApplicationFiled: October 29, 2004Publication date: February 8, 2007Inventors: Helena Ljusberg-Wahrén, Dan Lundberg, Krister Holmberg
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Publication number: 20060073203Abstract: The present invention provides an orally administrable composition comprising a dry mixture of polymer, lipid and bioactive agent, being capable on contact with water or GI tract liquid of forming particles comprising said lipid and said bioactive agent and optionally also water. It is preferable that such particles have a liquid crystalline phase structure. The invention also provides a method for the formation of compositions comprising polymer, lipid and bioactive agent.Type: ApplicationFiled: March 12, 2004Publication date: April 6, 2006Applicant: CAMURUS ABInventors: Helena Ljusberg-Wahren, Fredrik Joabsson, Krister Thuresson
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Patent number: 7004974Abstract: The invention relates to a preparation for restoring bone in the body of humans or animals in connection with an existing structure, a bone implant or some other prosthetic construction, as well as a method for restoring bone. The bone restoring preparation consists of an easily handleable and controllable preparation (composition) of resorbable calcium phosphate granules and a carrier of a biopolymer or lipid type. The preparation is intended to be applied in the position where the bone needs to be replaced, reinforced or built up, especially in connection with a bone implant or some other prosthetic construction where there is a lack of sufficient bone volume, or where the quality of the bone is too poor to allow a load-carrying function, for example permanent fixing of an implant.Type: GrantFiled: July 6, 1999Date of Patent: February 28, 2006Assignee: Nobel Biocare AB (publ.)Inventors: Cecilia Larsson, Helena Ljusberg-Wahren
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Patent number: 6660278Abstract: A controlled release composition for a biologically active material, which composition is liquid or liquid crystalline and comprises at least one medium or long-chain fatty acid ester of diglycerol as a carrier for said biologically active material, said biologically active material being dissolved or dispersed in said carrier. Said composition is especially useful as a medical composition.Type: GrantFiled: July 8, 1999Date of Patent: December 9, 2003Assignee: GS Development ABInventors: Kåre Larsson, Helena Ljusberg-Wahren, Niels Krog
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Patent number: 6599517Abstract: A composition suitable for restoring bone tissue in a human or animal body, which comprises a solid, preferably particulate, calcium phosphate as a biocompatible bone tissue substitute material distributed in a lamellar liquid crystalline phase comprising at least one phospholipid and water or other aqueous liquid as a bioacceptable carrier therefor, said lamellar crystalline phase being pre-formed or being formed in situ in said body in the presence of said water or other aqueous liquid, e.g., body fluid.Type: GrantFiled: April 16, 2001Date of Patent: July 29, 2003Assignee: Camarus ABInventors: Helena Ljusberg-Wahren, Nils Danielsen
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Patent number: 5906831Abstract: A controlled-release composition for a biologically active material, characterized in that it comprises a mixture of: a) monocaproin, optionally in admixture with moncaprylin and/or monocaprin, and b) a polar liquid selected from the group consisting of such polar liquids which are capable of forming an L2 phase with a), and c) a biologically active material dissolved or dispersed in said mixture of a) and b), a) being present in the composition, based on the total weight of a)+b), in an amount of from the lower limit where the mixture of a) and b) forms a reversed micellar (L2) structure and up to 100% by weight of a), with the further proviso that said mixture of a) and b) is essentially within that specific domain of the L2 structure, in a phase diagram, where said L2 structure will change to a normal micellar (L1) structure if contacted with an external polar liquid. Said composition is preferably used as a medial composition.Type: GrantFiled: April 29, 1997Date of Patent: May 25, 1999Assignee: GS Development ABInventors: K.ang.re Larsson, Helena Ljusberg-Wahren
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Patent number: 5807573Abstract: A biologically active composition containing (a) a diacyl glycerol, (b) a phospholipid and, optionally, (c) a polar liquid in such proportions that they together form an L2-phase or a cubic liquid crystalline phase, in which a biologically active material is dissolved or dispersed. A method for preparing the composition by mixing (a), (b) and, optionally, (c) for forming an L2-phase or a cubic liquid crystalline phase, the biologically active material being added before, during or after the formation of said phase. Use of the L2-phase or the cubic liquid crystalline phase for encapsulating a biologically active material for obtaining a preparation is provided, which yields a controlled release of the biologically active material.Type: GrantFiled: November 27, 1996Date of Patent: September 15, 1998Assignee: GS Development ABInventors: Helena Ljusberg-Wahren, K.ang.re Larsson
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Patent number: 4957511Abstract: A dispersing agent for solid particles in water, which is a tall oil pitch partially esterified with a polyalkylene glycol mainly composed of ethylene oxide units of a molecular weight of above 600 or a monoester or monoether thereof and optionally also aminated having a residual acid value higher than 3, and a process for preparing said dispersing agent which comprises heating the two reactants at 200.degree.-285.degree. C. for so long that the maximum acid value of the reaction mixture at this temperature is reduced at least 2 units. The dispersing agent can be used to disperse coal particles in water.Type: GrantFiled: March 19, 1984Date of Patent: September 18, 1990Assignee: Bergvik Kemi ABInventor: Helena Ljusberg-Wahren
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Patent number: 4634450Abstract: A coal-water dispersion comprising coal particles dispersed in water and a dispersing agent comprising polymerized fatty acids, polymerized rosin acids and/or polymerized fatty or rosin acid derivatives which have been partially esterified with a polyalkylene glycol or monoester or monoether thereof, having a residual acid value higher than 3.Type: GrantFiled: July 3, 1984Date of Patent: January 6, 1987Assignees: Bergvik Kemi AB, Fluidcarbon International ABInventor: Helena Ljusberg-Wahren