Patents by Inventor Helena Santos-Rosa

Helena Santos-Rosa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and means of histone methylation
    Patent number: 7074578
    Abstract: This invention relates to the methylation of histones, in particular to a previously uncharacterised group of histone H3 methylases which comprise a SET domain and which methylate either lysine 4 within the amino tail of histone H3 or within the histone H3 core. Methylation by these methylases, in particular trimethylation, is shown to be important for transcriptional activity.
    Type: Grant
    Filed: May 2, 2002
    Date of Patent: July 11, 2006
    Assignee: Chroma Therapeutics LTD
    Inventors: Tony Kouzarides, Helena Santos-Rosa
  • Methods and means of histone methylation
    Publication number: 20040241756
    Abstract: This invention relates to the methylation of histones, in particular to a previously uncharacterised group of histone H3 methylases which comprise a SET domain and which methylate either lysine 4 within the amino tail of histone H3 or within the histone H3 core. Methylation by these methylases, in particular trimethylation, is shown to be important for transcriptional activity.
    Type: Application
    Filed: June 28, 2004
    Publication date: December 2, 2004
    Inventors: Tony Kouzarides, Helena Santos-Rosa