Patents by Inventor Helene Decornez

Helene Decornez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bicyclic compound and use thereof for inhibiting SUV39H2
    Patent number: 10508109
    Abstract: The present invention directs to a compound represented by formula (I).
    Type: Grant
    Filed: September 12, 2016
    Date of Patent: December 17, 2019
    Assignee: ONCOTHERAPY SCIENCE, INC.
    Inventors: Yo Matsuo, Shoji Hisada, Yusuke Nakamura, Anjan Chakrabarti, Manish Rawat, Sanjay Rai, Arvapalli Venkata Satyanarayana, Zhiyong Duan, Arindam Talukdar, Srinivas Ravula, Helene Decornez
  • BICYCLIC COMPOUND AND USE THEREOF FOR INHIBITING SUV39H2
    Publication number: 20180273529
    Abstract: The present invention directs to a compound represented by formula (I).
    Type: Application
    Filed: September 12, 2016
    Publication date: September 27, 2018
    Inventors: YO MATSUO, Shoji Hisada, Yusuke Nakamura, Anjan Chakrabarti, Manish Rawat, Sanjay Rai, Arvapalli Venkata Satyanarayana, Zhiyong Duan, Arindam Talukdar, Srinivas Ravula, Helene Decornez
  • IMIDAZO(4,5-B) PYRIDIN-2-YL AMIDES AS KV7 CHANNEL ACTIVATORS
    Publication number: 20170240547
    Abstract: Compounds represented by formula 1 can be potent and/or partially selective for the Kv7.2/7.3 heteromultimer. They may be useful in treating disorders related to seizures, pain, neurotransmitter release, etc.
    Type: Application
    Filed: May 10, 2017
    Publication date: August 24, 2017
    Inventors: Lynn Resnick, George T. Topalov, Steven A. Boyd, Justin K. Belardi, Charles A. Flentge, James S. Hale, Scott S. Harried, David A. Mareska, Kai Zhang, Charles R. Heap, Mark Hadden, Wenge Cui, Hélène Decornez, Shuang Liu
  • Imidazo(4,5-) pyridin-2-yl amides as K7 channel activators
    Patent number: 9650376
    Abstract: Compounds represented by formula 1 can be potent and/or partially selective for the Kv7.2/7.3 heteromultimer. They may be useful in treating disorders related to seizures, pain, neurotransmitter release, etc.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: May 16, 2017
    Assignee: KNOPP BIOSCIENCES LLC
    Inventors: Lynn Resnick, George T. Topalov, Steven A. Boyd, Justin K. Belardi, Charles A. Flentge, James S. Hale, Scott S. Harried, David A. Mareska, Kai Zhang, Charles R. Heap, Mark Hadden, Wenge Cui, Hélène Decornez, Shuang Liu
  • Tricyclic compounds and PBK inhibitors containing the same
    Patent number: 9453025
    Abstract: Tricyclic compounds are provided. These compounds are PBK inhibitors, and are useful for the treatment of PBK related diseases, including cancer.
    Type: Grant
    Filed: December 9, 2014
    Date of Patent: September 27, 2016
    Assignee: OncoTherapy Science, Inc.
    Inventors: Yusuke Nakamura, Yo Matsuo, Shoji Hisada, Feryan Ahmed, Raymond Huntley, Zohreh Sajjadi-Hashemi, David M. Jenkins, Robert B. Kargbo, Wenge Cui, Polivina Jolicia F. Gauuan, Joel R. Walker, Helene Decornez, Mahender Gurram
  • IMIDAZO(4,5-B) PYRIDIN-2-YL AMIDES AS KV7 CHANNEL ACTIVATORS
    Publication number: 20160031875
    Abstract: Compounds represented by formula 1 can be potent and/or partially selective for the Kv7.2/7.3 heteromultimer. They may be useful in treating disorders related to seizures, pain, neurotransmitter release, etc.
    Type: Application
    Filed: March 17, 2014
    Publication date: February 4, 2016
    Inventors: Lynn Resnick, George T. Topalov, Steven A. Boyd, Justin K. Belardi, Charles A. Flentge, James S. Hale, Scott S. Harried, David A. Mareska, Kai Zhang, Charles R. Heap, Mark Hadden, Wenge Cui, Hélène Decornez, Shuang Liu
  • Quinoline derivatives and MELK inhibitors containing the same
    Patent number: 9120749
    Abstract: The present invention directs a compound represented by formula (I).
    Type: Grant
    Filed: July 28, 2011
    Date of Patent: September 1, 2015
    Assignee: ONCOTHERAPY SCIENCE, INC.
    Inventors: Yo Matsuo, Shoji Hisada, Yusuke Nakamura, Feryan Ahmed, Raymond Huntley, Joel R. Walker, Helene Decornez
  • Tricyclic Compounds and PBK Inhibitors Containing the Same
    Publication number: 20150183799
    Abstract: Tricyclic compounds are provided. These compounds are PBK inhibitors, and are useful for the treatment of PBK related diseases, including cancer.
    Type: Application
    Filed: December 9, 2014
    Publication date: July 2, 2015
    Inventors: Yusuke NAKAMURA, Matsuo YO, Shoji HISADA, Feryan AHMED, Raymond HUNTLEY, Zohreh SAJJADI-HASHEMI, David M. JENKINS, Robert B. KARGBO, Wenge CUI, Polivina Jolicia F. GAUUAN, Joel R. WALKER, Helene DECORNEZ, Mahender GURRAM
  • Tricyclic compounds and PBK inhibitors containing the same
    Patent number: 8962648
    Abstract: Tricyclic compounds are provided. These compounds are PBK inhibitors, and are useful for the treatment of PBK related diseases, including cancer.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: February 24, 2015
    Assignee: OncoTherapy Science, Inc.
    Inventors: Yusuke Nakamura, Yo Matsuo, Shoji Hisada, Feryan Ahmed, Raymond Huntley, Zohreh Sajjadi-Hashemi, David M. Jenkins, Robert B. Kargbo, Wenge Cui, Polivina Jolicia F. Gauuan, Joel R. Walker, Helene Decornez, Mahender Gurram
  • TRICYCLIC COMPOUNDS AND PBK INHIBITORS CONTAINING THE SAME
    Publication number: 20130178459
    Abstract: Tricyclic compounds are provided. These compounds are PBK inhibitors, and are useful for the treatment of PBK related diseases, including cancer.
    Type: Application
    Filed: March 29, 2011
    Publication date: July 11, 2013
    Applicant: Oncotherapy Science, Inc.
    Inventors: Yusuke Nakamura, Yo Matsuo, Shoji Hisada, Feryan Ahmed, Raymond Huntley, Zohreh Sajjadi-Hashemi, David M. Jenkins, Robert B. Kargbo, Wenge Cui, Polivina Jolicia F. Gauuan, Joel R. Walker, Helene Decornez, Mahender Gurram
  • AMINOPYRAZINE ANALOGS FOR TREATING GLAUCOMA AND OTHER RHO KINASE-MEDIATED DISEASES AND CONDITIONS
    Publication number: 20080269249
    Abstract: Methods for using aminopyrazine analogs to treat rho kinase-mediated diseases or rho kinase-mediated conditions, including controlling intraocular pressure and treating glaucoma, are disclosed. Ophthalmic pharmaceutical compositions useful in the treatment of eye diseases such as glaucoma, and additionally useful for controlling intraocular pressure, the compositions comprising an effective amount of aminopyrazine analogs, are also disclosed.
    Type: Application
    Filed: December 14, 2005
    Publication date: October 30, 2008
    Applicant: ALCON, INC.
    Inventors: Mark Hellberg, Andrew Rusinko, Alan Henderson, Cheng Guo, Mark Hadden, Helene Decornez
  • Heterocyclic compounds, methods of making them and their use in therapy
    Publication number: 20060183908
    Abstract: In part, the present invention is directed to antibacterial compounds of formula (I) wherein A is a bicyclic heteroaryl ring or a tricyclic ring and R2 is an heterocyclic residue; L is a bond, or L is alkyl, alkenyl or cycloalkyl.
    Type: Application
    Filed: December 5, 2003
    Publication date: August 17, 2006
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Judd Berman, Peter Sampson, Heinz Pauls, Jailall Ramnauth, David Douglas, Matthew Surman, Dejian Xie, Helene Decornez