Patents by Inventor Helene Dollfus

Helene Dollfus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF RETINAL DEGENERATION
    Publication number: 20170231930
    Abstract: The present invention relates to a pharmaceutical composition comprising an inhibitor of eIF2?, a compound increasing the expression and/or activity of protein BiP and/or an inhibitor of Caspase-12, preferably an inhibitor of eIF2? and a compound increasing the expression and/or activity of protein BiP. The present invention also relates to pharmaceutical compositions and methods for treating retinal degeneration related to ciliary dysfunction.
    Type: Application
    Filed: May 1, 2017
    Publication date: August 17, 2017
    Inventors: VINCENT MARION, ANAIS MOCKEL, HELENE DOLLFUS
  • Compositions and methods for the treatment of retinal degeneration
    Patent number: 9636377
    Abstract: The present invention relates to a pharmaceutical composition comprising an inhibitor of eIF2?, a compound increasing the expression and/or activity of protein BiP and/or an inhibitor of Caspase-12, preferably an inhibitor of eIF2? and a compound increasing the expression and/or activity of protein BiP. The present invention also relates to pharmaceutical compositions and methods for treating retinal degeneration related to ciliary dysfunction.
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: May 2, 2017
    Assignee: UNIVERSITE DE STRASBOURG
    Inventors: Vincent Marion, Anaïs Mockel, Hélène Dollfus
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF RETINAL DEGENERATION
    Publication number: 20150038432
    Abstract: The present invention relates to a pharmaceutical composition comprising an inhibitor of eIF2?, a compound increasing the expression and/or activity of protein BiP and/or an inhibitor of Caspase-12, preferably an inhibitor of eIF2? and a compound increasing the expression and/or activity of protein BiP. The present invention also relates to pharmaceutical compositions and methods for treating retinal degeneration related to ciliary dysfunction.
    Type: Application
    Filed: February 25, 2013
    Publication date: February 5, 2015
    Applicant: UNIVERSITE DE STRASBOURG
    Inventors: Vincent Marion, Anaïs Mockel, Hélène Dollfus
  • BBS10 related diagnostic methods for Bardet-Biedl syndrome
    Patent number: 8163482
    Abstract: The present invention relates to the identification of a gene, designated BBS1O, that is involved in the genetic disease Bardet Biedl Syndrome (BBS), which is characterized by such diverse symptoms as obesity, diabetes, hypertension, mental retardation, renal cancer and other abnormalities, retinopathy and hypogonadism. Methods of use for the gene, for example in diagnosis and therapy of BBS, also are described.
    Type: Grant
    Filed: February 23, 2007
    Date of Patent: April 24, 2012
    Inventors: Nicholas Katsanis, Helene Dollfus, Corinne Stoetzel, Erica E. Davis, Philip L. Beales, Jean-Louis Mandel, Richard Alan Lewis
  • BBS10 RELATED DIAGNOSTIC METHODS AND REAGENTS FOR BARDET-BIEDL SYNDROME
    Publication number: 20100130429
    Abstract: The present invention relates to the identification of a gene, designated BBS1O, that is involved in the genetic disease Bardet Biedl Syndrome (BBS), which is characterized by such diverse symptoms as obesity, diabetes, hypertension, mental retardation, renal cancer and other abnormalities, retinopathy and hypogonadism. Methods of use for the gene, for example in diagnosis and therapy of BBS, also are described.
    Type: Application
    Filed: February 23, 2007
    Publication date: May 27, 2010
    Inventors: Nicholas Katsanis, Helene Dollfus, Corinne Stoetzel, Erica E. Davis, Philip Beals, Jean-Louis Mandel, Richard Alan Lewis