Patents by Inventor Helene FAESSEL

Helene FAESSEL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OREXIN RECEPTOR 2 (OX2R) AGONIST FOR USE IN NARCOLEPSY TYPE 1 (NT1)
    Publication number: 20250375417
    Abstract: Disclosed herein are methods, uses and composition for treating narcolepsy with cataplexy (narcolepsy type 1 or NT1), blunted nocturnal blood pressure dip in a subject having narcolepsy type 1 or cognitive impairment in a subject having narcolepsy type 1, by administering an orexin receptor 2 agonist to the subject at one or more daily dosages.
    Type: Application
    Filed: April 30, 2025
    Publication date: December 11, 2025
    Inventors: Anson ABRAHAM, Helene FAESSEL, Yaming HANG, Brian HAREL, Marta KARAS, Haruhide KIMURA, Elena KOUNDOURAKIS, Tina OLSSON, Christian VON HEHN, Sebastian Philipp VON ROSENSTIEL, Vikram SINHA, Dmitri VOLFSON, Hao WANG, Andy ZHU
  • TAK-925 FOR USE IN TREATING NARCOLEPSY
    Publication number: 20220339143
    Abstract: A method for treating narcolepsy type 1 in a subject in need thereof is disclosed, comprising administering to the subject an effective amount of methyl 3-((methylsulfonyl)anhino)-2-(((4-phenylcyclohexyl)oxy)methyl)piperidine-1-carboxylate (Compound (I)), or a salt thereof, wherein plasma concentration for Compound (I) is about 5.04 ng/mL or more for about 1 hour or more. Compositions for treating narcolepsy type 1 comprising Compound (I) are also disclosed.
    Type: Application
    Filed: September 12, 2020
    Publication date: October 27, 2022
    Inventors: Deborah HARTMAN, Rebecca EVANS, Helene FAESSEL, Shinichiro TANAKA
  • USE OF AN OREXIN 2 RECEPTOR AGONIST FOR THE TREATMENT OF EXCESSIVE SLEEPINESS
    Publication number: 20220331303
    Abstract: Described herein are methyl 3-((methylsulfonyl)amino)-2-(((4-phenylcyclohexyl)oxy)methyl)-piperidine-1-carboxylate (Compound (I)), compositions comprising Compound (I), and the use of Compound (I) for the treatment of excessive sleepiness in a subject in need thereof.
    Type: Application
    Filed: September 12, 2020
    Publication date: October 20, 2022
    Inventors: Deborah HARTMAN, Rebecca EVANS, Helene FAESSEL, Robert RUBENS, Shinichiro TANAKA