Patents by Inventor Helene Henmar

Helene Henmar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide combinations and uses thereof for treating grass allergy
    Patent number: 11013781
    Abstract: The invention relates to combinations of peptides derived from a portion of an amino sequence of a grass pollen allergen, e.g. the allergens Phl p 1, Phl p 2, Phl p 3, Phl p 4 and/or Phl p 5, or a peptide variant thereof. Such peptides comprise at least one T cell epitope mid a high number of patients in a worldwide population will have HLA Class II alleles with the potential to bind the peptides of the peptide combinations. The invention also relates to the use of such peptide combinations in relieving an immune response caused by grass pollen species.
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: May 25, 2021
    Assignees: ALK-ABELLÓ AS, LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY
    Inventors: Claus Lundegaard, Shashank Gupta, Bjoern Peters, Susanne Sønderkær, Jens Brimnes, Peter Adler Würtzen, Helene Henmar, Thomas Christian Mygind, Lise Lund Mærkedahl, Alessandro Sette
  • PEPTIDE COMBINATIONS AND USES THEREOF FOR TREATING GRASS ALLERGY
    Publication number: 20180207228
    Abstract: The invention relates to combinations of peptides derived from a portion of an amino sequence of a grass pollen allergen, e.g. the allergens Phl p 1, Phl p 2, Phl p 3, Phl p 4 and/or Phl p 5, or a peptide variant thereof. Such peptides comprise at least one T cell epitope mid a high number of patients in a worldwide population will have HLA Class II alleles with the potential to bind the peptides of the peptide combinations. The invention also relates to the use of such peptide combinations in relieving an immune response caused by grass pollen species.
    Type: Application
    Filed: July 1, 2016
    Publication date: July 26, 2018
    Applicants: ALK-Abelló A/S
    Inventors: Claus Lundegaard, Shashank Gupta, Bjoern Peters, Susanne Sønderkær, Jens Brimnes, Peter Adler Würtzen, Helene Henmar, Thomas Christian Mygind, Lise Lund Mærkedahl
  • PLANT PROFILIN POLYPEPTIDES FOR USE IN NON-SPECIFIC ALLERGY IMMUNOTHERAPY
    Publication number: 20150126459
    Abstract: The invention relates to the treatment of a hypersensitivity immune response caused by a non-profilin allergen of a profilin-containing plant material (e.g. grass or tree pollen) by bystander suppression with a plant profilin (e.g. Phl p 12, Bet v 2, or Ole e 2) or a variant thereof. Also the invention features a particular variant of Phl p 12 with two of its cysteine residues replaced with another amino acid to increase its pharmaceutical properties.
    Type: Application
    Filed: April 16, 2013
    Publication date: May 7, 2015
    Inventors: Kaare Lund, Jens Brimnes, Helene Henmar, Hans-Henrik Ipsen, Lise Lund Mærkedahl, Gitte Nordskov Hansen, Rafael Ignacio Monsalve Clemente