Patents by Inventor Helge Hartenhauer

Helge Hartenhauer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the production of moxonidine
    Patent number: 9040697
    Abstract: 4,6-dichloro-2-methyl-5-(1-acyl-2-imidazolin-2-yl)-aminopyrimidine is reacted with methanol in the presence of a non-ionic organic base, and moxonidine is obtained directly from the reaction mixture.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: May 26, 2015
    Assignee: AREVIPHARMA GmbH
    Inventors: Harald Hofmeier, Michael Limmert, Heike Heydemüller, Helge Hartenhauer
  • 3-[3-(DIMETHYLAMINO)-1-ETHYL-2-METHYLPROPYL]PHENOL RESIN COMPLEX
    Publication number: 20140356314
    Abstract: The present invention discloses a 3-[3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol resin complex, preferably an amorphous 3-[3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol resin complex formed by the reaction between a cation exchange resin and 3-[3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol or a pharmaceutically acceptable acid addition salt thereof. It can exhibit an in-vitro release rate of 3-[3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol from the 3-[3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol resin complex which is in accordance with the requirements of Ph. Eur. on “conventional-release dosage forms”.
    Type: Application
    Filed: May 30, 2014
    Publication date: December 4, 2014
    Inventors: Helge HARTENHAUER, Michael LIMMERT
  • PROCESS FOR THE PRODUCTION OF MOXONIDINE
    Publication number: 20140228383
    Abstract: 4,6-dichloro-2-methyl-5-(1-acyl-2-imidazolin-2-yl)-aminopyrimidine is reacted with methanol in the presence of a non-ionic organic base, and moxonidine is obtained directly from the reaction mixture.
    Type: Application
    Filed: February 5, 2014
    Publication date: August 14, 2014
    Inventors: Harald HOFMEIER, Michael LIMMERT, Heike HEYDEMÜLLER, Helge HARTENHAUER
  • Novel hydroxyindoles, their use as inhibitors of phosphodiesterase 4, and processes for preparing them
    Publication number: 20070093531
    Abstract: The invention relates to substituted 4- or/and 7-hydroxyindoles, to processes for preparing them, to pharmaceutical preparations which comprise these compounds and to the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 4, as active compounds for treating diseases which can be influenced by using the compounds according to the invention to inhibit phosphodiesterase 4 activity in immunocompetent cells (e.g. macrophages and lympho-cytes).
    Type: Application
    Filed: November 30, 2006
    Publication date: April 26, 2007
    Inventors: Norbert Hofgen, Hildegard Kuss, Ute Egerland, Chris Rundfeldt, Helge Hartenhauer, Antje Gasparic
  • Hydroxyindoles, their use as inhibitors of phosphodiesterase 4, and processes for preparing them
    Patent number: 7166637
    Abstract: The invention relates to substituted 4- or/and 7-hydroxyindoles, to processes for preparing them, to pharmaceutical preparations which comprise these compounds and to the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 4, as active compounds for treating diseases which can be influenced by using the compounds according to the invention to inhibit phosphodiesterase 4 activity in immunocompetent cells (e.g. macrophages and lymphocytes).
    Type: Grant
    Filed: November 13, 2003
    Date of Patent: January 23, 2007
    Assignee: Elbion AG
    Inventors: Norbert Höfgen, Hildegard Kuss, Ute Egerland, Chris Rundfeldt, Helge Hartenhauer, Antje Gasparic
  • Process for preparing high-purity hydroxyindolylglyoxylamides
    Patent number: 7122674
    Abstract: The invention relates to a process for preparing hydroxyindolylglyoxylamides in high yields and particularly pure form.
    Type: Grant
    Filed: July 31, 2003
    Date of Patent: October 17, 2006
    Assignee: Elbion AG
    Inventors: Hans-Joachim Jänsch, Helge Hartenhauer, Hans Stange, Norbert Höfgen, Jürgen Schäfer
  • Novel hydroxyindoles, their use as inhibitors of phosphodiesterase 4, and processes for preparing them
    Publication number: 20040147759
    Abstract: The invention relates to substituted 4- or/and 7-hydroxyindoles, to processes for preparing them, to pharmaceutical preparations which comprise these compounds and to the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 4, as active compounds for treating diseases which can be influenced by using the compounds according to the invention to inhibit phosphodiesterase 4 activity in immunocompetent cells (e.g. macrophages and lymphocytes).
    Type: Application
    Filed: November 13, 2003
    Publication date: July 29, 2004
    Inventors: Norbert Hofgen, Hildegard Kuss, Ute Egerland, Chris Rundfeldt, Helge Hartenhauer, Antje Gasparic
  • Process for preparing high-purity hydroxyindolylglyoxylamides
    Publication number: 20040063939
    Abstract: The invention relates to a process for preparing hydroxyindolylglyoxylamides in high yields and particularly pure form.
    Type: Application
    Filed: July 31, 2003
    Publication date: April 1, 2004
    Inventors: Hans-Joachim Jansch, Helge Hartenhauer, Hans Stange, Norbert Hofgen, Jurgen Schafer