Patents by Inventor Helle Outtrup

Helle Outtrup has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA constructs and methods of producing cellulytic enzymes
    Publication number: 20030054534
    Abstract: An isolated nucleic acid constructs encoding cellulytic enzymes derived from a strain of Bacillus agaradherens, recombinant vectors and host cells comprising such constructs, and methods for obtaining cellulytic enzymes.
    Type: Application
    Filed: July 11, 2001
    Publication date: March 20, 2003
    Applicant: Novozymes A/S
    Inventors: Helle Outtrup, Claus Dambmann, Arne Agerlin Olsen, Henrik Bisgard-Frantzen, Martin Schulein, Per Linaa Jorgensen, Mads E. Bjoernvad
  • &agr;-amylase mutants
    Patent number: 6528298
    Abstract: The invention relates to a novel Termamyl-like &agr;-amylase, and Termamyl-like &agr;-amylases comprising mutations in two, three, four, five or six regions/positions. The variants have increased thermostability at acidic pH and/or at low Ca2+ concentrations (relative to the parent).
    Type: Grant
    Filed: April 7, 2000
    Date of Patent: March 4, 2003
    Assignee: Novozymes, A/S
    Inventors: Allan Svendsen, Torben Vedel Borchert, Henrik Bisgard-Frantzen, Helle Outtrup, Bjarne Ronfeldt Nielsen, Vibeke Skovgaard Nielsen, Lisbeth Hedegaard
  • Novel rhamnogalacturonan hydrolases
    Publication number: 20030026810
    Abstract: Novel isolated enzymes exhibiting rhamnogalacturonan hydrolase activity and belonging to a glycosyl hydrolase family other than family 28 are obtained and cloned from bacterial strains, for example, Bacillus licheniformis, Bacillus subtilis, Bacillus halodurans, Bacillus agaradhaerens, Caldicellulosiruptor, Streptomyces and Sorangium.
    Type: Application
    Filed: April 19, 2002
    Publication date: February 6, 2003
    Applicant: Novozymes A/S
    Inventors: Per Lina Jorgensen, Kirk Schnorr, Lene Nonboe Andersen, Martin Schulein, Hanne Dela, Helle Outtrup
  • Nucleic acids encoding polypeptides having proteolytic activity
    Patent number: 6511371
    Abstract: The present invention relates to isolated nucleic acid sequences encoding polypeptides having proteolytic activity. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as recombinant methods for producing the polypeptides.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: January 28, 2003
    Assignee: Novozymes, A/S
    Inventors: Helle Outtrup, Søren Flensted Lassen, Poul Erik Pedersen
  • Nucleic acids encoding polypeptides having proteolytic activity
    Publication number: 20020103100
    Abstract: The present invention relates to isolated nucleic acid sequences encoding polypeptides having proteolytic activity. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as recombinant methods for producing the polypeptides.
    Type: Application
    Filed: September 28, 2001
    Publication date: August 1, 2002
    Applicant: Novozymes A/S
    Inventors: Helle Outtrup, Soren Flensted Lassen, Poul Erik Pedersen
  • Rhamnogalacturonan hydrolases
    Patent number: 6399347
    Abstract: The present invention is directed to isolated enzymes exhibiting rhamnogalacturonan hydrolase activity, to nucleic acids encoding such enzymes, and to methods of producing such enzymes. The present invention is also related to detergent and animal feed compositions, compositions and methods for treating cellulosic materials, such as fibers, compositions and methods for preparing fruit or vegetable products, and compositions and methods for preparing wine and juice.
    Type: Grant
    Filed: May 13, 1999
    Date of Patent: June 4, 2002
    Assignee: Novozymes A/S
    Inventors: Per Linå Jørgensen, Kirk Schnorr, Lene Nonboe Andersen, Martin Schülein, Helle Outtrup
  • &agr;-amylase and &agr;-amylase variants
    Patent number: 6361989
    Abstract: The invention relates to a novel Termamyl-like &agr;-amylase, and Termamyl-like &agr;-amylases comprising mutations in two, three, four, five or six regions/positions. The variants have increased thermostability at acidic pH and/or at low Ca2+ concentrations (relative to the parent).
    Type: Grant
    Filed: April 13, 1999
    Date of Patent: March 26, 2002
    Assignee: Novozymes A/S
    Inventors: Allan Svendsen, Torben Vedel Borchert, Henrik Bisgard-Frantzen, Helle Outtrup, Bjarne Ronfeldt Nielsen, Vibeke Skovgaard Nielsen, Lisbeth Hedegaard
  • Mutants which produce a potentiator of bacillus pesticidal activity
    Publication number: 20020004237
    Abstract: This invention is directed to Bacillus mutants which produce a factor which potentiates the pesticidal activity of a Bacillus related pesticide, a chemical pesticide and/or a virus with pesticidal properties.
    Type: Application
    Filed: May 15, 2001
    Publication date: January 10, 2002
    Inventors: Helle Outtrup, William D. Lidster, Susan C. MacIntosh, Robert L. Starnes, Denise Carol Manker
  • Polypeptides having alkaline &agr;-amylase activity
    Patent number: 6309871
    Abstract: The present invention relates to isolated polypeptides having &agr;-amylase activity and isolated nucleic acid sequences encoding the polypeptides, which may be derived from Bacillus. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: April 13, 1999
    Date of Patent: October 30, 2001
    Assignee: Novozymes A/S
    Inventors: Helle Outtrup, Torben Vedel Borchert, Bjarne Ronfeldt Nielsen, Vibeke Skovgaard Nielsen, Lisbeth Hedegaard Hoeck
  • DNA constructs and methods of producing cellulytic enzymes
    Patent number: 6280984
    Abstract: An isolated nucleic acid constructs encoding cellulytic enzymes derived from a strain of Bacillus agaradherens, recombinant vectors and host cells comprising such constructs, and methods for obtaining cellulytic enzymes.
    Type: Grant
    Filed: January 7, 1999
    Date of Patent: August 28, 2001
    Assignee: Novozymes A/S
    Inventors: Helle Outtrup, Claus Dambmann, Arne Agerlin Olsen, Henrik Bisgård-Frantzen, Martin Schülein, Per Linaa Jorgensen, Mads E. Bjoernvad
  • Mutants which produce a potentiator of Bacillus pesticidal activity
    Patent number: 6277624
    Abstract: This invention is directed to Bacillus mutants which produce a factor which potentiates the pesticidal activity of a Bacillus related pesticide, a chemical pesticide and/or a virus with pesticidal properties.
    Type: Grant
    Filed: January 26, 1998
    Date of Patent: August 21, 2001
    Assignee: Valent BioSciences, Inc.
    Inventors: Helle Outtrup, William D. Lidster, Susan C. MacIntosh, Robert L. Starnes, Denise Carol Manker
  • Xyloglucan-specific alkaline xyloglucanase from bacillus
    Patent number: 6268197
    Abstract: A xyloglucanase having a relative xyloglucanase activity of at least 50% at pH 7 and either no or an insignificant cellulolytic activity is obtainable e.g. from a strain of Bacillus. A xyloglucanase comprising an amino acid sequence as shown in positions 30-261 of SEQ ID NO:2 or homologues may be derived from eg Bacillus licheniformis, ATCC 14580, and may be encoded by polynucleotide molecules comprising a nucleotide sequence as shown in SEQ ID NO:1 from nucleotide 88 to nucleotide 783; and a xyloglucanase comprising an amino acid sequence as shown in positions 1-537 of SEQ ID NO:4 or homologues may be derived from eg B. agaradhaerens, NCIMB 40482, and may be encoded by polynucleotide molecules comprising a nucleotide sequence as shown in SEQ ID NO:3 from nucleotide 1 to nucleotide 1611. The xyloglucanases are useful e.g. in cleaning compositions and for treatment of cellulosic fibres.
    Type: Grant
    Filed: July 7, 1998
    Date of Patent: July 31, 2001
    Assignee: Novozymes A/S
    Inventors: Martin Schulein, Helle Outtrup, Per Lina Jorgensen, Mads Eskelund Bjornvad
  • Alkalophilic Bacillus sp. AC13 and protease, xylanase, cellulase obtainable therefrom
    Patent number: 6017749
    Abstract: This invention relates to Alkalophilic Bacillus sp. AC13 microorganisms and cultures, and mutants and variants thereof, and to enzymes obtainable from the microorganism.
    Type: Grant
    Filed: February 10, 1998
    Date of Patent: January 25, 2000
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Claus Dambmann, Arne Agerlin Olsen, Henrik Bisg.ang.rd-Frantzen, Martin Schulein
  • Alkalophilic Bacillus sp. AC13 and protease, xylanase, cellulase obtainable therefrom
    Patent number: 5981253
    Abstract: The present invention relates to novel microorganisms, novel enzymes obtainable herefrom, and to a method of producing the novel enzymes. More specifically, the invention relates to novel enzymes obtainable from strains of the novel alkalophilic species Bacillus sp. AC13. Moreover, the invention relates to a method for producing the enzymes of the invention, and to the use of the enzymes in detergents or in the paper pulp industry.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: November 9, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Claus Dambmann, Arne Agerlin Olsen, Henrik Bisg.ang.rd-Frantzen, Martin Schulein
  • DNA constructs and methods of producing cellulytic enzymes
    Patent number: 5945327
    Abstract: An isolated nucleic acid constructs encoding cellulytic enzymes derived from a strain of Bacillus agaradherens, recombinant vectors and host cells comprising such constructs, and methods for obtaining cellulytic enzymes.
    Type: Grant
    Filed: June 6, 1997
    Date of Patent: August 31, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Claus Dambmann, Arne Agerlin Olsen, Henrik Bisg.ang.rd-Frantzen, Martin Schulein, Per Linaa Jorgensen, Mads E. Bjoernvad
  • Alkaline protease from bacillus sp.I612
    Patent number: 5928929
    Abstract: This invention is in the field of detergent proteases obtainable from strains of a new Bacillus sp. I 612. Moreover, the invention is directed towards a process for the preparation of the protease, the use of the protease as a detergent enzyme, and detergent compositions comprising the protease of the invention.
    Type: Grant
    Filed: July 2, 1997
    Date of Patent: July 27, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Lars Sparre Conrad
  • DNA constructs and methods of producing cellulytic enzymes
    Patent number: 5922586
    Abstract: An isolated nucleic acid constructs encoding cellulytic enzymes derived from a strain of Bacillus agaradherens, recombinant vectors and host cells comprising such constructs, and methods for obtaining cellulytic enzymes.
    Type: Grant
    Filed: September 13, 1996
    Date of Patent: July 13, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Claus Dambmann, Arne Agerlin Olsen, Henrik Bisg.ang.rd-Frantzen, Martin Schulein, Per Linaa Jorgensen, Mads E. Bjoernvad
  • Alkaline protease from Bacillus sp. ZI315
    Patent number: 5888797
    Abstract: This invention is in the field of detergent proteases obtainable from a strain of a new Bacillus sp. ZI 315. Moreover, the invention is directed towards a process for the preparation of the protease, the use of the protease as detergent enzyme, and detergent compositions comprising the protease of the invention.
    Type: Grant
    Filed: July 7, 1997
    Date of Patent: March 30, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Lars Sparre Conrad
  • Alkaline bacillus amylase
    Patent number: 5856164
    Abstract: An .alpha.-amylase characterized by having a specific activity at least 25% higher than the specific activity of Termamyl.RTM. at a temperature in the range of 25.degree. C. to 55.degree. C. and at a pH value in the range of pH 8 to pH 10.
    Type: Grant
    Filed: May 22, 1997
    Date of Patent: January 5, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Henrik Bisg.ang.rd-Frantzen, Peter Rahbek stergaard, Michael Dolberg Rasmussen, Pia Van Der Zee
  • Hypochlorite stable protease from bacillus SP., DSM 8473
    Patent number: 5856167
    Abstract: A protease obtained from Bacillus sp., DSM 8473, is disclosed which has improved hypochlorite stability as compared to other known proteases. The protease is suitable as a detergent additive and may be used singly or combined with other know enzymes in detergent compositions. A process for washing soiled fabric with detergent compositions containing the hypochlorite stable protease is also disclosed.
    Type: Grant
    Filed: February 14, 1996
    Date of Patent: January 5, 1999
    Assignee: Novo Nordisk A/S
    Inventor: Helle Outtrup