Patents by Inventor Hellmuth Reinshagen

Hellmuth Reinshagen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4485034
    Abstract: Oxalanilides of formula I ##STR1## in which R is C.sub.6-22 alkyl or C.sub.6-22 alkoxyR.sub.1 and R.sub.2 are independently, hydrogen, C.sub.1-8 alkyl, C.sub.1-12 alkoxy, C.sub.1-12 alkylthio, phenoxy or phenylthio; provided that R.sub.1 and R.sub.2 may not both be selected from alkylthio, phenoxy and phenylthio;and R.sub.3 is hydrogen or C.sub.1-8 alkylcertain of which are novel, are useful as UV-stabilizers in organic polymers and organic polymer-containing coatings, particularly automotive finishes. The compounds have low volatility and excellent solubility in organic solvents such as are used in liquid finishes.
    Type: Grant
    Filed: September 6, 1983
    Date of Patent: November 27, 1984
    Assignee: Sandoz Ltd.
    Inventors: Lajos Avar, Evelyne Kalt, Hellmuth Reinshagen
  • Patent number: 4415687
    Abstract: 1,3-dihydroxy-4,6-bis-4'-(2',2',6',6',-tetramethylpiperidyl) benzene, its 1'-alkyl or 1'-(substituted alkyl) derivatives and monomeric or polymeric products derived from these compounds by substitution of 1- and 3-hydroxy groups and/or by the linking of hydroxy groups on adjacent units through a bridging groups, are useful as light and heat stabilizers for polymeric organic materials.Corresponding bis(3',4'-dehydro) unsaturated compounds are useful as intermediates.
    Type: Grant
    Filed: July 2, 1982
    Date of Patent: November 15, 1983
    Assignee: Sandoz Ltd.
    Inventors: Lajos Avar, Evelyne Kalt, Hellmuth Reinshagen
  • Patent number: 4412024
    Abstract: Oxalanilides of formula I ##STR1## in which R is C.sub.6-22 alkyl or C.sub.6-22 alkoxyR.sub.1 and R.sub.2 are independently, hydrogen, C.sub.1-8 alkyl, C.sub.1-12 alkoxy, C.sub.1-12 alkylthio, phenoxy or phenylthio; provided that R.sub.1 and R.sub.2 may not both be selected from alkylthio, phenoxy and phenylthio;andR.sub.3 is hydrogen or C.sub.1-8 alkylcertain of which are novel, are useful as UV-stabilizers in organic polymers and organic polymer-containing coatings, particularly automotive finishes. The compounds have low volatility and excellent solubility in organic solvents such as are used in liquid finishes.
    Type: Grant
    Filed: September 14, 1981
    Date of Patent: October 25, 1983
    Assignee: Sandoz Ltd.
    Inventors: Lajos Avar, Evelyne Kalt, Hellmuth Reinshagen
  • Patent number: 4278674
    Abstract: This invention relates to new pleuromutilins of the formula: ##STR1## wherein either R.sub.1 is ethyl or vinyl,n is an integer from 2 to 5,x is sulphur,a group ##STR2## or a group .dbd.N--R.sub.4 .sup.I, wherein eitherY and Z are both sulphur, orone of Y and Z is oxygen and the other is sulphur, andR.sub.4.sup.I is hydrogen or a group of the formula: ##STR3## wherein R.sub.1 is as defined above, each of R.sub.2 and R.sub.3 is alkyl of 1 to 10 carbon atoms, orR.sub.2 and R.sub.3 together with the nitrogen atom form a heterocycle of 5 to 7 ring members containing one nitrogen atom or one nitrogen atom and a further hetero member selected from sulphur, oxygen and a group .dbd.N--R.sub.5.sup.I,wherein R.sub.5.sup.I is alkyl of 1 to 5 carbon atoms or hydroxyalkyl of 1 to 4 carbon atoms, orR.sub.2 and R.sub.3 together with the nitrogen atom form a piperazinyl radical, the second nitrogen atom of which is substituted by a radical R.sub.5.sup.II,whereby R.sub.5.sup.
    Type: Grant
    Filed: November 29, 1979
    Date of Patent: July 14, 1981
    Assignee: Sandoz Ltd.
    Inventors: Helmut Egger, Hellmuth Reinshagen
  • Patent number: 4208326
    Abstract: This invention relates to new pleuromutilins of the formula: ##STR1## wherein either R.sub.1 is ethyl or vinyl,n is an integer from 2 to 5,X is sulphur,a group ##STR2## or a group .dbd.N--R.sub.4.sup.I, whereineither Y and Z are both sulphur, orone of Y and Z is oxygen and the other is sulphur, andR.sub.4.sup.I is hydrogen or a group of the formula: ##STR3## wherein R.sub.1 is as defined above, each of R.sub.2 and R.sub.3 is alkyl of 1 to 10 carbon atoms, orR.sub.2 and R.sub.3 together with the nitrogen atom form a heterocycle of 5 to 7 ring members, and pharmaceutically acceptable acid addition salts and quaternary salts thereof.Processes for the preparation of such compounds are described.The compounds are antibiotics with an antibacterial effect.
    Type: Grant
    Filed: June 5, 1978
    Date of Patent: June 17, 1980
    Assignee: Sandoz Ltd.
    Inventors: Helmut Egger, Hellmuth Reinshagen
  • Patent number: 4112091
    Abstract: Inhibiting methanogenesis by adding polyhaloalkyl or alkenyl alcohol esters of piperazino acids of the formula ##STR1## wherein X and Z are oxygen or sulphur.
    Type: Grant
    Filed: April 4, 1977
    Date of Patent: September 5, 1978
    Assignee: Sandoz Ltd.
    Inventors: Hans Nesvadba, Hellmuth Reinshagen
  • Patent number: 4107164
    Abstract: This invention relates to new pleuromutilins of the formula: ##STR1## wherein EITHERR.sub.1 is ethyl or vinyl,N is an integer from 2 to 5,X is sulphur, a group ##STR2## or a group =N--R.sub.4 .sup.I, whereinWhereinEither Y and Z are both sulphur, orOne of Y and Z is oxygen and the other is sulphur, andR.sub.4.sup.i is hydrogen or a group of the formula: ##STR3## wherein R.sub.1 is as defined above,Each ofR.sub.2 and R.sub.3 is alkyl of 1 to 10 carbon atoms, orR.sub.2 and R.sub.3 together with the nitrogen atom form a heterocycle of 5 to 7 ring members,And pharmaceutically acceptable acid addition salts and quaternary salts thereof.Processes for the preparation of such compounds are described.The compounds are antibiotics with an antibacterial effect.
    Type: Grant
    Filed: January 10, 1977
    Date of Patent: August 15, 1978
    Assignee: Sandoz Ltd.
    Inventors: Helmut Egger, Hellmuth Reinshagen
  • Patent number: 4057557
    Abstract: The invention provides novel 5-nitrothiazolylimidazoline derivatives, useful as chemotherapeutic agents.
    Type: Grant
    Filed: February 6, 1976
    Date of Patent: November 8, 1977
    Assignee: Sandoz Ltd.
    Inventors: Gerd Ascher, Hellmuth Reinshagen
  • Patent number: 4055642
    Abstract: Basically substituted imidazolyl-2-quinazolines of the formula ##STR1## where R.sub.1 is hydrogen, lower alkyl or halogen;R.sub.2 is lower alkyl, lower alkenyl or lower hydroxalkyl; andR.sub.3 is a basic organic substituent,Are useful as anti-parasitic agents and as mycoplasma growth inhibiting agents.
    Type: Grant
    Filed: May 5, 1976
    Date of Patent: October 25, 1977
    Assignee: Sandoz Ltd.
    Inventors: Hans Nesvadba, Hellmuth Reinshagen
  • Patent number: 4055646
    Abstract: This invention provides novel 5-nitrothiazolo-2-imidazoles which are useful as chemotherapeutical agents.
    Type: Grant
    Filed: February 6, 1976
    Date of Patent: October 25, 1977
    Assignee: Sandoz Ltd.
    Inventors: Gerd Ascher, Hellmuth Reinshagen
  • Patent number: 4032530
    Abstract: This invention relates to new pleuromutilins of the formula: ##STR1## wherein EITHER R.sub.1 is ethyl or vinyl,n is an integer from 2 to 5,X is sulphur,A group ##STR2## or a group =N-R.sub.4.sup.I, whereinEither Y and Z are both sulphur, orOne of Y and Z is oxygen and the other is sulphur, andR.sub.4.sup.i is hydrogen or a group of the formula: ##STR3## wherein R.sub.1 is as defined above, EACH OFR.sub.2 and R.sub.3 is alkyl of 1 to 10 carbon atoms, orR.sub.2 and R.sub.3 together with the nitrogen atom form a heterocycle of 5 to 7 ring members containing one nitrogen atom or one nitrogen atom and a further hetero member selected from sulphur, oxygen and a group =N-R.sub.5.sup.I,wherein R.sub.5.sup.I is alkyl of 1 to 5 carbon atoms or hydroxyalkyl of 1 to 4 carbon atoms, orR.sub.2 and R.sub.3 together with the nitrogen atom form a piperazinyl radical, the second nitrogen atom of which is substituted by a radical R.sub.5.sup.II,whereby R.sub.5.sup.
    Type: Grant
    Filed: August 21, 1975
    Date of Patent: June 28, 1977
    Assignee: Sandoz Ltd.
    Inventors: Helmut Egger, Hellmuth Reinshagen
  • Patent number: 4020166
    Abstract: This invention provides compounds of the formula, ##STR1## in which R.sub.1 signifies straight or branched chain alkyl in which a single methyl group is replaced by a mono-, di- or tri-halomethyl group; R.sub.2 signifies hydrogen or straight or branched chain lower alkyl and X and Z each independently signifies oxygen or sulphur, which are useful as animal feed additives and amoebicidal agents.
    Type: Grant
    Filed: December 3, 1975
    Date of Patent: April 26, 1977
    Assignee: Sandoz, Ltd.
    Inventors: Hans Nesvadba, Hellmuth Reinshagen