Patents by Inventor Hellmuth Reinshagen
Hellmuth Reinshagen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 4485034Abstract: Oxalanilides of formula I ##STR1## in which R is C.sub.6-22 alkyl or C.sub.6-22 alkoxyR.sub.1 and R.sub.2 are independently, hydrogen, C.sub.1-8 alkyl, C.sub.1-12 alkoxy, C.sub.1-12 alkylthio, phenoxy or phenylthio; provided that R.sub.1 and R.sub.2 may not both be selected from alkylthio, phenoxy and phenylthio;and R.sub.3 is hydrogen or C.sub.1-8 alkylcertain of which are novel, are useful as UV-stabilizers in organic polymers and organic polymer-containing coatings, particularly automotive finishes. The compounds have low volatility and excellent solubility in organic solvents such as are used in liquid finishes.Type: GrantFiled: September 6, 1983Date of Patent: November 27, 1984Assignee: Sandoz Ltd.Inventors: Lajos Avar, Evelyne Kalt, Hellmuth Reinshagen
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Patent number: 4415687Abstract: 1,3-dihydroxy-4,6-bis-4'-(2',2',6',6',-tetramethylpiperidyl) benzene, its 1'-alkyl or 1'-(substituted alkyl) derivatives and monomeric or polymeric products derived from these compounds by substitution of 1- and 3-hydroxy groups and/or by the linking of hydroxy groups on adjacent units through a bridging groups, are useful as light and heat stabilizers for polymeric organic materials.Corresponding bis(3',4'-dehydro) unsaturated compounds are useful as intermediates.Type: GrantFiled: July 2, 1982Date of Patent: November 15, 1983Assignee: Sandoz Ltd.Inventors: Lajos Avar, Evelyne Kalt, Hellmuth Reinshagen
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Patent number: 4412024Abstract: Oxalanilides of formula I ##STR1## in which R is C.sub.6-22 alkyl or C.sub.6-22 alkoxyR.sub.1 and R.sub.2 are independently, hydrogen, C.sub.1-8 alkyl, C.sub.1-12 alkoxy, C.sub.1-12 alkylthio, phenoxy or phenylthio; provided that R.sub.1 and R.sub.2 may not both be selected from alkylthio, phenoxy and phenylthio;andR.sub.3 is hydrogen or C.sub.1-8 alkylcertain of which are novel, are useful as UV-stabilizers in organic polymers and organic polymer-containing coatings, particularly automotive finishes. The compounds have low volatility and excellent solubility in organic solvents such as are used in liquid finishes.Type: GrantFiled: September 14, 1981Date of Patent: October 25, 1983Assignee: Sandoz Ltd.Inventors: Lajos Avar, Evelyne Kalt, Hellmuth Reinshagen
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Patent number: 4278674Abstract: This invention relates to new pleuromutilins of the formula: ##STR1## wherein either R.sub.1 is ethyl or vinyl,n is an integer from 2 to 5,x is sulphur,a group ##STR2## or a group .dbd.N--R.sub.4 .sup.I, wherein eitherY and Z are both sulphur, orone of Y and Z is oxygen and the other is sulphur, andR.sub.4.sup.I is hydrogen or a group of the formula: ##STR3## wherein R.sub.1 is as defined above, each of R.sub.2 and R.sub.3 is alkyl of 1 to 10 carbon atoms, orR.sub.2 and R.sub.3 together with the nitrogen atom form a heterocycle of 5 to 7 ring members containing one nitrogen atom or one nitrogen atom and a further hetero member selected from sulphur, oxygen and a group .dbd.N--R.sub.5.sup.I,wherein R.sub.5.sup.I is alkyl of 1 to 5 carbon atoms or hydroxyalkyl of 1 to 4 carbon atoms, orR.sub.2 and R.sub.3 together with the nitrogen atom form a piperazinyl radical, the second nitrogen atom of which is substituted by a radical R.sub.5.sup.II,whereby R.sub.5.sup.Type: GrantFiled: November 29, 1979Date of Patent: July 14, 1981Assignee: Sandoz Ltd.Inventors: Helmut Egger, Hellmuth Reinshagen
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Patent number: 4208326Abstract: This invention relates to new pleuromutilins of the formula: ##STR1## wherein either R.sub.1 is ethyl or vinyl,n is an integer from 2 to 5,X is sulphur,a group ##STR2## or a group .dbd.N--R.sub.4.sup.I, whereineither Y and Z are both sulphur, orone of Y and Z is oxygen and the other is sulphur, andR.sub.4.sup.I is hydrogen or a group of the formula: ##STR3## wherein R.sub.1 is as defined above, each of R.sub.2 and R.sub.3 is alkyl of 1 to 10 carbon atoms, orR.sub.2 and R.sub.3 together with the nitrogen atom form a heterocycle of 5 to 7 ring members, and pharmaceutically acceptable acid addition salts and quaternary salts thereof.Processes for the preparation of such compounds are described.The compounds are antibiotics with an antibacterial effect.Type: GrantFiled: June 5, 1978Date of Patent: June 17, 1980Assignee: Sandoz Ltd.Inventors: Helmut Egger, Hellmuth Reinshagen
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Patent number: 4112091Abstract: Inhibiting methanogenesis by adding polyhaloalkyl or alkenyl alcohol esters of piperazino acids of the formula ##STR1## wherein X and Z are oxygen or sulphur.Type: GrantFiled: April 4, 1977Date of Patent: September 5, 1978Assignee: Sandoz Ltd.Inventors: Hans Nesvadba, Hellmuth Reinshagen
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Patent number: 4107164Abstract: This invention relates to new pleuromutilins of the formula: ##STR1## wherein EITHERR.sub.1 is ethyl or vinyl,N is an integer from 2 to 5,X is sulphur, a group ##STR2## or a group =N--R.sub.4 .sup.I, whereinWhereinEither Y and Z are both sulphur, orOne of Y and Z is oxygen and the other is sulphur, andR.sub.4.sup.i is hydrogen or a group of the formula: ##STR3## wherein R.sub.1 is as defined above,Each ofR.sub.2 and R.sub.3 is alkyl of 1 to 10 carbon atoms, orR.sub.2 and R.sub.3 together with the nitrogen atom form a heterocycle of 5 to 7 ring members,And pharmaceutically acceptable acid addition salts and quaternary salts thereof.Processes for the preparation of such compounds are described.The compounds are antibiotics with an antibacterial effect.Type: GrantFiled: January 10, 1977Date of Patent: August 15, 1978Assignee: Sandoz Ltd.Inventors: Helmut Egger, Hellmuth Reinshagen
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Patent number: 4057557Abstract: The invention provides novel 5-nitrothiazolylimidazoline derivatives, useful as chemotherapeutic agents.Type: GrantFiled: February 6, 1976Date of Patent: November 8, 1977Assignee: Sandoz Ltd.Inventors: Gerd Ascher, Hellmuth Reinshagen
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Patent number: 4055642Abstract: Basically substituted imidazolyl-2-quinazolines of the formula ##STR1## where R.sub.1 is hydrogen, lower alkyl or halogen;R.sub.2 is lower alkyl, lower alkenyl or lower hydroxalkyl; andR.sub.3 is a basic organic substituent,Are useful as anti-parasitic agents and as mycoplasma growth inhibiting agents.Type: GrantFiled: May 5, 1976Date of Patent: October 25, 1977Assignee: Sandoz Ltd.Inventors: Hans Nesvadba, Hellmuth Reinshagen
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Patent number: 4055646Abstract: This invention provides novel 5-nitrothiazolo-2-imidazoles which are useful as chemotherapeutical agents.Type: GrantFiled: February 6, 1976Date of Patent: October 25, 1977Assignee: Sandoz Ltd.Inventors: Gerd Ascher, Hellmuth Reinshagen
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Patent number: 4032530Abstract: This invention relates to new pleuromutilins of the formula: ##STR1## wherein EITHER R.sub.1 is ethyl or vinyl,n is an integer from 2 to 5,X is sulphur,A group ##STR2## or a group =N-R.sub.4.sup.I, whereinEither Y and Z are both sulphur, orOne of Y and Z is oxygen and the other is sulphur, andR.sub.4.sup.i is hydrogen or a group of the formula: ##STR3## wherein R.sub.1 is as defined above, EACH OFR.sub.2 and R.sub.3 is alkyl of 1 to 10 carbon atoms, orR.sub.2 and R.sub.3 together with the nitrogen atom form a heterocycle of 5 to 7 ring members containing one nitrogen atom or one nitrogen atom and a further hetero member selected from sulphur, oxygen and a group =N-R.sub.5.sup.I,wherein R.sub.5.sup.I is alkyl of 1 to 5 carbon atoms or hydroxyalkyl of 1 to 4 carbon atoms, orR.sub.2 and R.sub.3 together with the nitrogen atom form a piperazinyl radical, the second nitrogen atom of which is substituted by a radical R.sub.5.sup.II,whereby R.sub.5.sup.Type: GrantFiled: August 21, 1975Date of Patent: June 28, 1977Assignee: Sandoz Ltd.Inventors: Helmut Egger, Hellmuth Reinshagen
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Patent number: 4020166Abstract: This invention provides compounds of the formula, ##STR1## in which R.sub.1 signifies straight or branched chain alkyl in which a single methyl group is replaced by a mono-, di- or tri-halomethyl group; R.sub.2 signifies hydrogen or straight or branched chain lower alkyl and X and Z each independently signifies oxygen or sulphur, which are useful as animal feed additives and amoebicidal agents.Type: GrantFiled: December 3, 1975Date of Patent: April 26, 1977Assignee: Sandoz, Ltd.Inventors: Hans Nesvadba, Hellmuth Reinshagen