Patents by Inventor Helmut Ballhause

Helmut Ballhause has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 6-benzyl-2H-3,4,5,6-tetrahydro-(1,3)-oxazines
    Patent number: 5114935
    Abstract: Novel compounds of the general formula ##STR1## which have antitussive activity, wherein R.sub.1 -R.sub.4 are as defined herein.
    Type: Grant
    Filed: August 15, 1990
    Date of Patent: May 19, 1992
    Assignee: Dr. Karl Thomae GmbH
    Inventors: Helmut Ballhause, Gunther Engelhardt, Claus A. Landgraf, Norbert Mayer, Willy Roth, Kurt Schumacher, Alex Prox
  • Quaternary 3,4-dihydro-isoquinolinium salts
    Patent number: 4678792
    Abstract: This invention relates to a compound of formula (I) ##STR1## wherein R.sub.1 and R.sub.2 are each independently hydrogen, C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.3 alkoxy; and R.sub.3 is a C.sub.7 -C.sub.9 aralkyl, the phenyl nucleus of which can be mono-, di-, or trisubstituted by halogen, C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.3 alkoxy, and nontoxic, pharmaceutically acceptable salts thereof. The compounds have useful antithrombic properties.
    Type: Grant
    Filed: February 28, 1985
    Date of Patent: July 7, 1987
    Assignee: Dr. Karl Thomae GmbH
    Inventors: Josef Nickl, Erich Muller, Benthold Narr, Helmut Ballhause, Walter Haarmann
  • Amino-benzoic acid amides
    Patent number: 4093734
    Abstract: Compounds of the formula ##STR1## wherein (A) WHEN THE AMINO-SUBSTITUENT IS IN THE P-POSITION WITH RESPECT TO THE CARBONYL GROUP,R.sub.1 is chlorine in the o-position with respect to the carbonyl group,R.sub.2 is hydrogen, andR.sub.3 is ethylamino, cyclopentylamino, cyclohexylamino, cycloheptylamino, N-methyl-cyclohexylamino, benzylamino or 1-ethyl-pyrrolidyl-(2)-aminomethyl, or(b) when the amino-substituent is in the o--, m-- or p-position with respect to the carbonyl group,R.sub.1 is hydrogen, chlorine or bromine,R.sub.2 is trifluoromethyl, nitro or, when R.sub.4 is 1-(alkyl of 1 to 3 carbon atoms)-pyrrolidyl or 1-(alkyl of 1 to 3 carbon atoms)-piperidyl, also fluorine, chlorine, bromine or methyl,R.sub.3 is (alkyl of 1 to 5 carbon atoms)-amino, (cycloalkyl of 3 to 7 carbon atoms)-amino, benzylamino, quinuclidinyl-amino or --NH--(CH.sub.2).sub.n --R.sub.4where R.sub.
    Type: Grant
    Filed: October 22, 1976
    Date of Patent: June 6, 1978
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Gerd Kruger, Johannes Keck, Klaus Reinhold Noll, Helmut Pieper, Harald Ziegler, Helmut Ballhause, Joachim Kahling