Patents by Inventor Helmut Bomches

Helmut Bomches has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Melfloquin hydrochloride
    Patent number: 4579855
    Abstract: Mefloquin hydrochloride in the form of modification E as characterized by IR spectrum and X-ray diffraction pattern, as well as a process for the preparation thereof by treating mefloquin hydrochloride, comprising at least partially another modification, that is, mefloquin hydrochloride which is not pure mefloquin hydrochloride in the form of modification E, with methanol and/or ethanol, in the presence of less than 30 volume/percent of water.
    Type: Grant
    Filed: October 1, 1984
    Date of Patent: April 1, 1986
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Helmut Bomches, Bruno Hardegger
  • Purification of mefloquin hydrochloride
    Patent number: 4507482
    Abstract: A method for obtaining mefloquin hydrochloride, erythro-.alpha.-2-piperidyl-2,8-bis-(trifluoromethyl)-4-quinolinemethanol hydrochloride, from mixtures of erythro-and threo-.alpha.-2-piperidyl-2,8-bis-(trifluoromethyl)-4-quinolinemethanol hydrochloride by treatment with aqueous methanol or ethanol. The thermodynamically most stable form is obtained by treatment with an alcohol/water mixture for a long period of time.
    Type: Grant
    Filed: April 4, 1983
    Date of Patent: March 26, 1985
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Helmut Bomches, Bruno Hardegger