Abstract: A method for producing a detection system for biomolecules in a medium involves providing a first detector section having a first channel region and a second detector section having a second channel region. A membrane having at least one pore is provided and the first detector section and the second detector section are arranged on opposite sides of the membrane, such that at least part of the first channel region and the second channel region are separated by the membrane and the first channel region and the second channel region are connected to each another to form a channel system, in order to form a flow path for the medium through the at least one pore of the membrane. Along the flow path, through the membrane, bioreceptors are bound and/or coupled to the membrane in order to determine a concentration of the biomolecules in the medium by means of a measurement of the flow along the flow path.

Abstract: A device for deflecting light through 180.degree. characterized by a directional coupler comprising a pair of strip waveguides formed on a substrate with the end faces of the pair of strip waveguides being provided with a mirror. The directional coupler may be formed as a half of a coupler with the mirror effectively bisecting the length of the coupler, or it may be a .DELTA..beta. reversible directional coupler which is the whole length or as a half of a directional coupler. In addition, the directional coupler may be a controllable power dividing coupler and a phase shifter may be applied on one of the waveguides of the coupler. The device can also be utilized in a spectral comb filter.