Patents by Inventor Helmut Hagen

Helmut Hagen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of isoxazolin-3-ylacylbenzenes
    Patent number: 8124810
    Abstract: A process is described for preparing isoxazoles of the formula I where the substituents are as defined below: R1 is hydrogen, C1-C6-alkyl, R2 is C1-C6-alkyl, R3, R4, R5 are hydrogen, C1-C6-alkyl, or R4 and R5 together form a bond, R6 is a heterocyclic ring, n is 0, 1 or 2; which comprises preparing an intermediate of the formula VI where R1, R3, R4 and R5 are as defined above, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of the formula I. Also novel intermediates for preparing the compounds of the formula I and novel processes for preparing the intermediates are described.
    Type: Grant
    Filed: January 4, 2010
    Date of Patent: February 28, 2012
    Assignee: BASF SE
    Inventors: Joachim Rheinheimer, Wolfgang von Deyn, Joachim Gebhardt, Michael Rack, Rene Lochtman, Norbert Götz, Michael Keil, Matthias Witschel, Helmut Hagen, Ulf Miβlitz, Ernst Baumann
  • Preparation of isoxazolin-3-ylacylbenzenes
    Patent number: 8049017
    Abstract: A process is described for preparing isoxazoles of the formula I where the substituents are as defined below: R1 is hydrogen, C1-C6-alkyl, R2 is C1-C6-alkyl, R3, R4, R5 are hydrogen, C1-C6-alkyl, or R4 and R5 together form a bond, R6 is a heterocyclic ring, n is 0, 1 or 2; which comprises preparing an intermediate of the formula VI where R1, R3, R4 and R5 are as defined above, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of the formula I. Also novel intermediates for preparing the compounds of the formula I and novel processes for preparing the intermediates are described.
    Type: Grant
    Filed: March 2, 2011
    Date of Patent: November 1, 2011
    Assignee: BASF SE
    Inventors: Joachim Rheinheimer, Wolfgang von Deyn, Joachim Gebhardt, Michael Rack, Rene Lochtman, Norbert Götz, Michael Keil, Matthias Witschel, Helmut Hagen, Ulf Miβlitz, Ernst Baumann
  • PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES
    Publication number: 20110152535
    Abstract: A process is described for preparing isoxazoles of the formula I where the substituents are as defined below: R1 is hydrogen, C1-C6-alkyl, R2 is C1-C6-alkyl, R3, R4, R5 are hydrogen, C1-C6-alkyl, or R4 and R5 together form a bond, R6 is a heterocyclic ring, n is 0, 1 or 2; which comprises preparing an intermediate of the formula VI where R1, R3, R4 and R5 are as defined above, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of the formula I. Also novel intermediates for preparing the compounds of the formula I and novel processes for preparing the intermediates are described.
    Type: Application
    Filed: March 2, 2011
    Publication date: June 23, 2011
    Inventors: Joachim Rheinheimer, Wolfgang von Deyn, Joachim Gebhardt, Michael Rack, Rene Lochtman, Norbert Götz, Michael Keil, Matthias Witschel, Helmut Hagen, Ulf Mißlitz, Ernst Baumann
  • PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES
    Publication number: 20100105920
    Abstract: A process is described for preparing isoxazoles of the formula I where the substituents are as defined below: R1 is hydrogen, C1-C6-alkyl, R2 is C1-C6-alkyl, R3, R4, R5 are hydrogen, C1-C6-alkyl, or R4 and R5 together form a bond, R6 is a heterocyclic ring, n is 0, 1 or 2; which comprises preparing an intermediate of the formula VI where R1, R3, R4 and R5 are as defined above, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of the formula I. Also novel intermediates for preparing the compounds of the formula I and novel processes for preparing the intermediates are described.
    Type: Application
    Filed: January 4, 2010
    Publication date: April 29, 2010
    Inventors: Joachim Rheinheimer, Wolfgang von Deyn, Joachim Gebhardt, Michael Rack, Rene Lochtman, Norbert Götz, Michael Keil, Matthias Witschel, Helmut Hagen, Ulf Misslitz, Ernst Baumann
  • Preparation of isoxazolin-3-ylacylbenzene
    Patent number: 7663001
    Abstract: A process is described for preparing isoxazoles of the formula I where the substituents are as defined below: R1 is hydrogen, C1-C6-alkyl, R2 is C1-C6-alkyl, R3, R4, R5 are hydrogen, C1-C6-alkyl, or R4 and R5 together form a bond, R6 is a heterocyclic ring, n is 0, 1 or 2; which comprises preparing an intermediate of the formula VI where R1, R3, R4 and R5 are as defined above, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of the formula I. Also novel intermediates for preparing the compounds of the formula I and novel processes for preparing the intermediates are described.
    Type: Grant
    Filed: March 11, 2007
    Date of Patent: February 16, 2010
    Assignee: BASF Aktiengesellschaft
    Inventors: Joachim Rheinheimer, Wolfgang von Deyn, Joachim Gebhardt, Michael Rack, Rene Lochtman, Norbert Götz, Michael Keil, Matthias Witschel, Helmut Hagen, Ulf Miβlitz, Ernst Baumann
  • Preparation of isoxazolin-3-ylacylbenzene
    Patent number: 7309802
    Abstract: A process is described for preparing isoxazoles of the formula I where the substituents are as defined below: R1 is hydrogen, C1-C6-alkyl, R2 is C1-C6-alkyl, R3, R4, R5 are hydrogen, C1-C6-alkyl, or R4 and R5 together form a bond, R6 is a heterocyclic ring, n is 0, 1 or 2; which comprises preparing an intermediate of the formula VI where R1, R3, R4 and R5 are as defined above, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of the formula I. Also novel intermediates for preparing the compounds of the formula I and novel processes for preparing the intermediates are described.
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: December 18, 2007
    Assignee: BASF Aktiengesellschaft
    Inventors: Joachim Rheinheimer, Wolfgang von Deyn, Joachim Gebhardt, Michael Rack, Rene Lochtman, Norbert Götz, Michael Keil, Matthias Witschel, Helmut Hagen, Ulf Misslitz, Ernst Baumann
  • Preparation of Isoxazolin-3-Ylacylbenzene
    Publication number: 20070161800
    Abstract: A process is described for preparing isoxazoles of the formula I where the substituents are as defined below: R1 is hydrogen, C1-C6-alkyl, R2 is C1-C6-alkyl, R3, R4, R5 are hydrogen, C1-C6-alkyl, or R4 and R5 together form a bond, R6 is a heterocyclic ring, n is 0, 1 or 2; which comprises preparing an intermediate of the formula VI where R1, R3, R4 and R5 are as defined above, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of the formula I. Also novel intermediates for preparing the compounds of the formula I and novel processes for preparing the intermediates are described.
    Type: Application
    Filed: March 11, 2007
    Publication date: July 12, 2007
    Inventors: Joachim Rheinheimer, Wolfgang von Deyn, Joachim Gebhardt, Michael Rack, Rene Lochtman, Norbert Gotz, Michael Keil, Matthias Witschel, Helmut Hagen, Ulf Misslitz, Ernst Boumann
  • Preparation of 2-alkyl-3-(4,5-dihydroisoxazol-3-yl) halobenzenes
    Patent number: 6716989
    Abstract: A novel process for preparing the compounds of the formula I where: n is 0, 1 or 2; R1, R2 are C1-C6-alkyl; R3, R4, R5 are hydrogen or C1-C6-alkyl, or R4 and R5 together form a bond; R6 is Cl, Br, which comprises a synthesis sequence starting from 1,2-dialkylbenzenes of the formula II with subsequent halogenation to give 3,6-dihalo-1,2-dialkylbenzenes, haloalkylation to give benzyl bromides, oxidation to give benzaldehydes, oximation, reaction with alkenes to give isoxazoles, conversion into thioethers and, if appropriate, oxidation to give sulfenyl or sulfonyl derivatives of the formula I.
    Type: Grant
    Filed: June 18, 2003
    Date of Patent: April 6, 2004
    Assignee: BASF Aktiengesellschaft
    Inventors: Michael Rack, Norbert Götz, Helmut Hagen, Wolfgang von Deyn, Ernst Baumann, Rene Lochtman, Joachim Gebhardt
  • Process and novel intermediates for preparing isoxazolin-3-ylacyl benzenes
    Patent number: 6706886
    Abstract: The present invention describes a process for preparing isoxazoles of the formula I where: R1 is hydrogen, C1-C6-alkyl, R2 is hydrogen, C1-C6-alkyl, R3, R4, R5 are each hydrogen, C1-C6-alkyl or R4 and R5 together form a bond, R6 is a heterocyclic ring, n is 0, 1 or 2; which comprises preparing an intermediate of the formula VI where R1, R3, R4 and R5 are each as defined above, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of the formula I. Furthermore, the invention describes novel intermediates for preparing the compounds of the formula I and novel processes for preparing the intermediates.
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: March 16, 2004
    Assignee: BASF Aktiengesellschaft
    Inventors: Wolfgang von Deyn, Joachim Gebhardt, Michael Rack, Rene Lochtman, Norbert Götz, Michael Keil, Matthias Witschel, Helmut Hagen, Ulf Misslitz, Ernst Baumann
  • Process and novel intermediates for preparing isoxazolin-3-ylacyl benzenes
    Patent number: 6670482
    Abstract: The present invention describes a process for preparing isoxazoles of the formula I where: R1 is hydrogen, C1-C6-alkyl, R2 is hydrogen, C1-C6-alkyl, R3, R4, R5 are each hydrogen, C1-C6-alkyl or R4 and R5 together form a bond, R6 is a heterocyclic ring, n is 0, 1 or 2; which comprises preparing an intermediate of the formula VI where R1, R3, R4 and R5 are each as defined above, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of the formula I. Furthermore, the invention describes novel intermediates for preparing the compounds of the formula I and novel processes for preparing the intermediates.
    Type: Grant
    Filed: August 19, 2002
    Date of Patent: December 30, 2003
    Assignee: BASF Aktiengesellschaft
    Inventors: Wolfgang von Deyn, Joachim Gebhardt, Michael Rack, Rene Lochtman, Norbert Götz, Michael Keil, Matthias Witschel, Helmut Hagen, Ulf Misslitz, Ernst Baumann
  • PREPARATION OF 2-ALKYL-3-(4,5-DIHYDROISOXAZOL-3-YL) HALOBENZENES
    Publication number: 20030229232
    Abstract: A novel process for preparing the compounds of the formula I 1
    Type: Application
    Filed: June 18, 2003
    Publication date: December 11, 2003
    Inventors: Michael Rack, Norbert Gotz, Helmut Hagen, Wolfgang von Deyn, Ernst Baumann, Rene Lochtman, Joachim Gebhardt
  • Process and novel intermediates for preparing isoxazolin-3-ylacyl benzenes
    Publication number: 20030220505
    Abstract: The present invention describes a process for preparing isoxazoles of the formula I 1
    Type: Application
    Filed: May 14, 2003
    Publication date: November 27, 2003
    Inventors: Wolfgang von Deyn, Joachim Gebhardt, Michael Rack, Rene Lochtman, Norbert Gotz, Michael Keil, Matthias Witschel, Helmut Hagen, Ulf Misslitz, Ernst Baumann
  • Preparation of Isoxazolin-3-Ylacylbenzene
    Publication number: 20030216580
    Abstract: A process is described for preparing isoxazoles of the formula I 1
    Type: Application
    Filed: April 17, 2003
    Publication date: November 20, 2003
    Inventors: Joachim Rheinheimer, Wolfgang von Deyn, Joachim Gebhardt, Michael Rack, Rene Lochtman, Norbert Gotz, Michael Keil, Matthias Witschel, Helmut Hagen, Ulf Misslitz, Ernst Baumann
  • Preparation of isoxazolin-3-ylacylbenzenes
    Patent number: 6608209
    Abstract: A process is described for preparing isoxazoles of the formula I wherein R1 is hydrogen, C1-C6-alkyl, R2 is C1-C6-alkyl, R3, R4, R5 are hydrogen, C1-C6-alkyl, or R4 and R5 together form a bond, R6 is a heterocyclic ring, n is 0, 1 or 2; in which an intermediate of the formula VI  is prepared, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of formula I. Novel intermediates for preparing the intermediates are described.
    Type: Grant
    Filed: June 27, 2002
    Date of Patent: August 19, 2003
    Assignee: BASF Aktiengesellschaft
    Inventors: Joachim Rheinheimer, Wolfgang von Deyn, Joachim Gebhardt, Michael Rack, Rene Lochtman, Norbert Götz, Michael Keil, Matthias Witschel, Helmut Hagen, Ulf Misslitz, Ernst Baumann
  • Preparation of 2-alkyl-3-(4,5-dihydroisoxazol-3-yl) halobenzenes
    Patent number: 6603017
    Abstract: A novel process for preparing the compounds of the formula I where: n is 0, 1 or 2; R1, R2 are C1-C6-alkyl; R3, R4, R5 are hydrogen or C1-C6-alkyl, or R4 and R5 together form a bond; R6 is Cl, Br, which comprises a synthesis sequence starting from 1,2-dialkylbenzenes of the formula II with subsequent halogenation to give 3,6-dihalo-1,2-dialkylbenzenes, haloalkylation to give benzyl bromides, oxidation to give benzaldehydes, oximation, reaction with alkenes to give isoxazoles, conversion into thioethers and, if appropriate, oxidation to give sulfenyl or sulfonyl derivatives of the formula I.
    Type: Grant
    Filed: May 9, 2002
    Date of Patent: August 5, 2003
    Assignee: BASF Aktiengesellschaft
    Inventors: Michael Rack, Norbert Götz, Helmut Hagen, Wolfgang von Deyn, Ernst Baumann, Rene Lochtman, Joachim Gebhardt
  • Method of producing 2-alkyl-3-(4,5-dihydroisoxazole-3-yl)-halobenzenes
    Patent number: 6548677
    Abstract: A novel process for preparing the compounds of the formula I where: n is 0, 1 or 2; R1, R2 are C1-C6-alkyl; R3, R4, R5 are hydrogen or C1-C6-alkyl, or R4 and R5 together form a bond; R6 is Cl, Br, which comprises a synthesis sequence starting from 1,2-dialkylbenzenes of the formula II with subsequent halogenation to give 3,6-dihalo-1,2-dialkylbenzenes, haloalkylation to give benzyl bromides, oxidation to give benzaldehydes, oximation, reaction with alkenes to give isoxazoles, conversion into thioethers and, if appropriate, oxidation to give sulfenyl or sulfonyl derivatives of the formula I.
    Type: Grant
    Filed: May 17, 2001
    Date of Patent: April 15, 2003
    Assignee: BASF Aktiengesellschaft
    Inventors: Michael Rack, Norbert Götz, Helmut Hagen, Wolfgang von Deyn, Ernst Baumann, Rene Lochtman, Joachim Gebhardt
  • Method for producing isoxazoline-3-yl-acyl benzene
    Patent number: 6525204
    Abstract: A process is described for preparing isoxazol-3-ylacylbenzenes. Also, novel intermediates for preparing isoxazol-3-ylacylbenzenes and novel processes for preparing the intermediates are described.
    Type: Grant
    Filed: November 2, 2000
    Date of Patent: February 25, 2003
    Assignee: BASF Aktiengesellschaft
    Inventors: Joachim Rheinheimer, Wolfgang von Deyn, Joachim Gebhardt, Michael Rack, Rene Lochtman, Norbert Götz, Michael Keil, Matthias Witschel, Helmut Hagen, Ulf Misslitz, Ernst Baumann
  • Process and novel intermediates for preparing isoxazolin-3-ylacyl benzenes
    Publication number: 20030028033
    Abstract: The present invention describes a process for preparing isoxazoles of the formula I 1
    Type: Application
    Filed: August 19, 2002
    Publication date: February 6, 2003
    Inventors: Wolfgang von Deyn, Joachim Gebhardt, Michael Rack, Rene Lochtman, Norbert Gotz, Michael Keil, Matthias Witschel, Helmut Hagen, Ulf Miblitz, Ernst Baumann
  • Preparation of isoxazolin-3-ylacylbenzenes
    Publication number: 20030018200
    Abstract: A process is described for preparing isoxazoles of the formula I 1
    Type: Application
    Filed: June 27, 2002
    Publication date: January 23, 2003
    Inventors: Joachim Rheinheimer, Wolfgang Von Deyn, Joachim Gebhardt, Michael Rack, Rene Lochtman, Norbert Gotz, Michael Keil, Matthias Witschel, Helmut Hagen, Ulf Misslitz, Ernst Baumann
  • Preparation of 2-alkyl-3-(4,5-dihydroisoxazol-3-yl) halobenzenes
    Publication number: 20020156290
    Abstract: A novel process for preparing the compounds of the formula I 1
    Type: Application
    Filed: May 9, 2002
    Publication date: October 24, 2002
    Inventors: Michael Rack, Norbert Gotz, Helmut Hagen, Wolfgang von Deyn, Ernst Baumann, Rene Lochtman, Joachim Gebhardt