Patents by Inventor Helmut Heber

Helmut Heber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of the C1 inactivator
    Patent number: 4915945
    Abstract: The invention relates to a process for the preparation of C1 inactivator, which, if appropriate, is hepatitis-free and, if appropriate, can be lyophilized, and its use as a medicament.
    Type: Grant
    Filed: April 18, 1985
    Date of Patent: April 10, 1990
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Hermann Pelzer, Helmut Heber, Norbert Heimburger, Hans M. Preis, Horst Naumann
  • Chromogenic compounds, a process for their preparation and their use
    Patent number: 4665016
    Abstract: Chromogenic compounds of the formula I ##STR1## and a process for their preparation are described, X denoting a hydrogen atom, a protective group customarily used in peptide chemistry or a group which irreversibly blocks the terminal amino group,A and P being identical or different and denoting an alpha-, beta- or gamma-amino acid which is composed of 2 to 15 carbon atoms with up to 3 nitrogen atoms, 2 sulfur atoms and 6 oxygen atoms, the side-chain of which can be substituted, and P also denoting a dipeptide formed from amino acids of these types,B denoting arginine, homoarginine, lysine, homolysine, ornithine or histidine andR denoting a substituent in the 2- or 3-position.The compounds can be used as substrates for the direction and the quantitative determination of hydrolytic enzymes of enzyme class 3.4.21.
    Type: Grant
    Filed: March 21, 1986
    Date of Patent: May 12, 1987
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Helmut Heber, Reinhard Eberle, Volker Teetz
  • Chromogenic compounds, a process for their preparation and their use
    Patent number: 4508644
    Abstract: Chromogenic compounds of the formula I ##STR1## and a process for their preparation are described, X denoting a hydrogen atom, a protective group customarily used in peptide chemistry or a group which irreversibly blocks the terminal amino group,A and P being identical or different and denoting an alpha-, beta- or gamma-amino acid which is composed of 2 to 15 carbon atoms with up to 3 nitrogen atoms, 2 sulfur atoms and 6 oxygen atoms, the side-chain of which can be substituted, and P also denoting a dipeptide formed from amino acids of these types,B denoting arginine, homoarginine, lysine, homolysine, ornithine or histidine andR denoting a substituent in the 2- or 3-position.The compounds can be used as substrates for the detection and the quantitative determination of hydrolytic enzymes of enzyme class 3.4.21.
    Type: Grant
    Filed: November 25, 1983
    Date of Patent: April 2, 1985
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Helmut Heber, Reinhard Eberle, Volker Teetz
  • Chromogenic compounds and their use as enzyme substrates
    Patent number: 4457866
    Abstract: What are disclosed are chromogenic peptides useful as substrates for the detection and determination of enzymes having a hydrolytic action and methods for detecting and determining enzymes with such peptides.
    Type: Grant
    Filed: October 19, 1982
    Date of Patent: July 3, 1984
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Hermann E. Karges, Helmut Heber, Rainer Uhmann, Volker Teetz, Rolf Geiger
  • Process for the preparation of plasminogen and plasminogen thus prepared
    Patent number: 4442213
    Abstract: What is disclosed is a process for rendering plasminogen virtually free of hepatitis virus by heating a plasminogen solution in the presence of a proteinase inhibitor with plasmin specificity, an amino acid, and a saccharide or sugar alcohol.
    Type: Grant
    Filed: May 12, 1982
    Date of Patent: April 10, 1984
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Helmut Heber, Horst Schwinn, Norbert Heimburger, Gerhardt Kumpe, Manfred Schick