Patents by Inventor Helmut Reubold

Helmut Reubold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-(hetero)-aryl substituted tetrahydroquinoline derivatives
    Patent number: 7868172
    Abstract: Compounds of the formula I, in which W, R, R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in Claim 1, can be employed, inter alia, for the treatment of tumours
    Type: Grant
    Filed: December 14, 2004
    Date of Patent: January 11, 2011
    Assignee: Merck Patent GmbH
    Inventors: Kai Schiemann, Ulrich Emde, Dirk Finsinger, Johannes Gleitz, Helmut Reubold, Frank Zenke
  • Method for producing-2[-5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane
    Patent number: 7045629
    Abstract: The present invention relates to a process for the preparation of 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chroman, the enantiomers and its salts, characterised in that 5-(4-fluorophenyl)pyridine-3-carbaldehyde is reacted directly with aminomethylchroman or its salts under reducing conditions to give 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chroman, and the latter is, if desired, converted into one of its physiologically acceptable salts by treatment with an acid.
    Type: Grant
    Filed: April 8, 2002
    Date of Patent: May 16, 2006
    Assignee: Merck Patent GmbH
    Inventors: Heinz-Hermann Bokel, Steffen Neuenfeld, Ludwig Gantzert, Ralf Knierieme, Elke Simon, Ralf Devant, Udo Helm, Helmut Reubold
  • Method for producing-2[-5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane
    Publication number: 20040138266
    Abstract: The present invention relates to a process for the preparation of 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chroman, the enantiomers and its salts, characterised in that 5-(4-fluorophenyl)pyridine-3-carbaldehyde is reacted directly with aminomethylchroman or its salts under reducing conditions to give 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chroman, and the latter is, if desired, converted into one of its physiologically acceptable salts by treatment with an acid.
    Type: Application
    Filed: October 27, 2003
    Publication date: July 15, 2004
    Inventors: Heinz-Hermann Bokel, Steffen Neuenfeld, Ludwig Gantzert, Ralf Knierieme, Elke Simon, Ralf Devant, Udo Helm, Helmut Reubold