Abstract: Disclosed is an adjusting mechanism for rotating the adjusting shaft of a variable valve control device for combustion engines, in which the crank of a crank-rocker mechanism or slider-crank mechanism is mounted on the camshaft and in which the rocker of the crank-rocker mechanism or the slider of the slider-crank mechanism can entrain the adjusting shaft in the desired direction of rotation by means of switchable freewheels.

Abstract: A method for producing solid proteinase K which is insoluble in water and has high purity, the method comprising the steps of adding to an aqueous solution of proteinase K ammonium sulfate in an amount of 0.1 to 0.2 M per 5 minutes up to a final amount of 1.5 to 2 M after 1 hour, thereby precipitating the proteinase K as a solid, and isolating the solid proteinase K.

Abstract: Disclosed is an adjusting mechanism for rotating the adjusting shaft of a variable valve control device for combustion engines, in which the crank of a crank-rocker mechanism or slider-crank mechanism is mounted on the camshaft and in which the rocker of the crank-rocker mechanism or the slider of the slider-crank mechanism can entrain the adjusting shaft in the desired direction of rotation by means of switchable freewheels.

Abstract: The invention relates to a device for the variable actuation of the gas exchange valves of internal combustion engines, whereby a continuously revolving cam drives an intermediate member which carries out an oscillating, pure rotational movement and moves a drive member in accordance with the respective valve lift curve via a control cam. In order to modify the valve lift curve, the position of the rotational axis of the intermediate member can be modified along an advance curve. The rotational axis of the intermediate member is represented by a pin which is freely rotatable at its guide end and which carries cam plates that are linked therewith in a rotationally fixed manner. Said cam plates define either directly or indirectly the respective required position on the advance curve. The pin is rotated via a suitable joining element.

Abstract: The invention concerns a method for the expression of a gene coding for a soluble proteinase K in yeast e.g. in Pichia pastoris with subsequent secretion into the culture medium. In addition a method for purifying the heterologously expressed and secreted proteinase K is described.

Abstract: The invention is characterized in that the gas exchange valves of a cylinder are displaced in a displacement unit (15, 34) jointly and independently of the displacement of the displacement devices of the other cylinders. Every displacement unit (15, 34) is associated with separate actuators for actuating the same. Angle of rotation sensors (42, 43) are provided to detect the angle or rotation signals of the crankshaft and the camshaft or any other shaft rotating at half the crankshaft speed. These angle of rotation signals are used to derive the common idle phase of all valves of a cylinder to be jointly adjusted, a control unit (44) effecting the displacement of every displacement unit (15, 34) during said common idle phase.

Abstract: The invention relates to a device for the variable actuation of gas exchange valves for internal combustion engines, wherein at least one cam (2) pertaining to a camshaft (1) mounted in a housing rotates according to the engine speed. The cam (2) first drives an intermediate member (4) which performs a clear oscillating, rotary movement and has a rotational axis (7) that can be displaced in the housing parallel to itself along a curve of displacement (8), said intermediate member comprising a control cam (5) having a lifting region (5b) and actuating an output member (11) that, in turn, actuates at least one valve (13). The aim of the invention is to enable one such device to be reliably controlled.

Abstract: A method for producing solid proteinase K which is insoluble in water and has high purity, the method comprising the steps of adding to an aqueous solution of proteinase K ammonium sulfate in an amount of 0.1 to 0.2 M per 5 minutes up to a final amount of 1.5 to 2 M after 1 hour, thereby precipitating the proteinase K as a solid, and isolating the solid proteinase K.

Abstract: The invention concerns recombinant proteinase K. Furthermore a method for producing recombinant proteinase K is disclosed, which is characterized in that a) a host cell is transformed with a recombinant nucleic acid which codes for the zymogenic precursor of proteinase K, b) the host cell is cultured in such a manner that the zymogenic precursor of proteinase K is formed in the form of inclusion bodies in the host cell, c) the inclusion bodies are isolated and natured under conditions which result in the formation of the protease part of the zymogenic precursor in its natural conformation, d) the natured proteinase K is activated and purified.

Abstract: The invention relates to a revolving gear consisting of a housing (G), a shaft (W), an intermediate member (Z) and an output member (A). The shaft is revolvably guided in the housing in a rotating joint (wb) and actuates the intermediate member by means of a curved joint (zw). The intermediate member is supported by a curved joint (zg) in the housing and is actively connected to the output member by another curved joint (za). The curved joint between the intermediate member and the housing has a controlling section enabling movement to be transmitted to the output member and a locking section preventing movement from being transmitted to the output member. The output member is unequivocally guided in the housing and transmits movement to at least one valve (V).

Abstract: A method is provided for the production of a bovine pancreatic protein with a specific desoxyribonuclease activity of at least 6,000 units per mg of protein. Methylotrophic yeast is used as a heterologous host organism. The bovine pancreatic protein is secreted into the growth medium from which it is purified.

Abstract: The aim of the invention is to fulfill, in a way that is superior to that of the previous state of the art, the demands placed by the engine on a variable valve control with regard to the shaping and accuracy of the valve lifting curves, to the simplicity of the structural design of the valve drive and of the associated adjusting mechanism, and to mechanical losses due to friction. These demands are met without any additional structural complexity, and, more particularly, without any changes to the overall height. This feat is achieved by means of the provision of a rotatable drive consisting of a housing (G), a shaft (W), an intermediate element (Z), and of an output element (A).

Abstract: A method is provided for the production of a bovine pancreatic protein with a specific desoxyribonuclease activity of at least 6,000 units per mg of protein. Methylotrophic yeast is used as a heterologous host organism. The bovine pancreatic protein is secreted into the growth medium from which it is purified.

Abstract: According to the invention, the desoxyribonuclease with increased thermolability is a variant, by way of amino acid substitution, of bovine pancreatic desoxyribonuclease I. The variant protein retains desoxyribonuclease activity. Moreover, the specific desoxyribonuclease activity of the variant of bovine pancreatic desoxyribonuclease I is approximately zero units per mg of protein following heating of the variant of bovine pancreatic desoxyribonuclease I for about 5 min at a temperature below 95° C. In addition, the variant of bovine pancreatic desoxyribonuclease I has no measurable ribonuclease activity.

Abstract: The invention concerns a method for the expression of a gene coding for a soluble proteinase K in yeast e.g. in Pichia pastoris with subsequent secretion into the culture medium. In addition a method for purifying the heterologously expressed and secreted proteinase K is described.