Patents by Inventor Helmut Sies

Helmut Sies has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FLAVANOL AND CAROTENOID COMPOSITIONS
    Publication number: 20140045932
    Abstract: This invention relates to compositions containing polyphenols, for example, cocoa polyphenols such as flavanols and their related oligomers, and methods for treating abnormalities in gap junctional communication of cells, such as cancer, heart arrhythmia, neuro-degenerative diseases and cognitive dysfunction.
    Type: Application
    Filed: October 23, 2013
    Publication date: February 13, 2014
    Applicant: MARS, INCORPORATED
    Inventor: Helmut SIES
  • Cognitive function
    Patent number: 8568805
    Abstract: This invention relates to compositions containing polyphenols, for example, cocoa polyphenols such as flavanols and their related oligomers, and methods for treating abnormalities in gap junctional communication of cells, such as cancer, heart arrhythmia, neuro-degenerative diseases and cognitive dysfunction.
    Type: Grant
    Filed: March 2, 2009
    Date of Patent: October 29, 2013
    Assignee: Mars, Inc.
    Inventor: Helmut Sies
  • Cognitive Function
    Publication number: 20090182037
    Abstract: This invention relates to compositions containing polyphenols, for example, cocoa polyphenols such as flavanols and their related oligomers, and methods for treating abnormalities in gap junctional communication of cells, such as cancer, heart arrhythmia, neuro-degenerative diseases and cognitive dysfunction.
    Type: Application
    Filed: March 2, 2009
    Publication date: July 16, 2009
    Applicant: Mars, Incorporated
    Inventor: Helmut Sies
  • Treatment of diseases involving defective gap junctional communication
    Patent number: 7514107
    Abstract: This invention relates to compositions containing polyphenols, for example, cocoa polyphenols such as flavanols and their related oligomers, and methods for treating abnormalities in gap junctional communication of cells, such as cancer, heart arrhythmia, neuro-degenerative diseases and cognitive dysfunction.
    Type: Grant
    Filed: March 20, 2003
    Date of Patent: April 7, 2009
    Assignee: Mars, Incorporated
    Inventor: Helmut Sies
  • Skin protection and improvement
    Publication number: 20070148107
    Abstract: This invention relates to compositions, and methods of use thereof, for (i) reducing ultraviolet (UV)-induced skin erythema and/or photoaging, and for (ii) improving skin quality, each method comprising orally administering to a subject in need thereof, certain polyphenols described herein such as flavanols, procyanidins, or pharmaceutically acceptable salts or derivatives thereof.
    Type: Application
    Filed: December 21, 2006
    Publication date: June 28, 2007
    Applicant: Mars, Incorporated
    Inventors: Helmut Sies, Wilhelm Stahl
  • Use of gamma-GT inhibitors for the treatment of degenerative diseases
    Publication number: 20040115284
    Abstract: Use of &ggr;-GT inhibitors for the preparation of a pharmaceutical composition for the treatment of a degenerative disease, in particular of chronic renal diseases or inner ear degenerative diseases.
    Type: Application
    Filed: August 19, 2003
    Publication date: June 17, 2004
    Inventors: Hans Weiher, Helmut Sies, Gunter Wagner
  • Treatment of diseases involving defective gap junctional communication
    Publication number: 20030180406
    Abstract: This invention relates to compositions containing polyphenols, for example, cocoa polyphenols such as flavanols and their related oligomers, and methods for treating abnormalities in gap junctional communication of cells, such as cancer, heart arrhythmia, neuro-degenerative diseases and cognitive dysfunction.
    Type: Application
    Filed: March 20, 2003
    Publication date: September 25, 2003
    Inventor: Helmut Sies
  • S-[2-phenyl (alkyl) carbamoyl]-phenylselenylmercapto derivatives
    Patent number: 4730053
    Abstract: The present invention is related to new S-(Carbamoyl-phenylselenyl) derivatives of mercaptanes of the general formula (I) ##STR1## and to a process for the treatment of diseases caused by cell injury due to the increased formation of active oxygen metabolites.
    Type: Grant
    Filed: November 25, 1985
    Date of Patent: March 8, 1988
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Norbert Dereu, Albrecht Wendel, Helmut Sies, Sigurd Leyck, Axel Romer, Erich Graf
  • S-(carbamoyl-phenylselenyl) derivatives of glutathione and of aminomercaptocarboxylic acids
    Patent number: 4618669
    Abstract: The present invention relates to new S-(carbamoylphenylselenyl) derivatives of glutathione and of .alpha.
    Type: Grant
    Filed: June 14, 1985
    Date of Patent: October 21, 1986
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Norbert Dereu, Andre Welter, Albrecht Wendel, Sigurd Leyck, Michael Parnham, Erich Graf, Helmut Sies, Hans Betzing, Hartmut Fischer