Patents by Inventor Helmut Sonnenschein

Helmut Sonnenschein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-amino-1,5,6,7-tetrahydro-4H-indol-4-ones
    Patent number: 10428044
    Abstract: Compounds of formula (I) which are inhibitors of Bub1 kinase, processes for their production and their use as pharmaceuticals.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: October 1, 2019
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Keith Graham, Ulrich Klar, Hans Briem, Marion Hitchcock, Lars Bärfacker, Knut Eis, Volker Schulze, Gerhard Siemeister, Wilhelm Bone, Jens Schröder, Simon Holton, Philip Lienau, René Tempel, Helmut Sonnenschein, Jozsef Bálint, Heinz Graubaum
  • Process or preparing spirocyclic cyclohexane compounds, compositions containing such compounds and method of using such compounds
    Patent number: 9862719
    Abstract: Spirocyclic cyclohexane compounds corresponding to formula I a method for producing them, pharmaceutical compositions containing them, and methods of using them.
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: January 9, 2018
    Assignee: Gruenenthal GmbH
    Inventors: Claudia Hinze, Otto Aulenbacher, Bernd Sundermann, Stefan Oberboersch, Elmar Friderichs, Werner Englberger, Babette-Yvonne Koegel, Klaus Linz, Hans Schick, Helmut Sonnenschein, Birgitta Henkel, Valerie Sarah Rose, Michael Jonathan Lipkin
  • 3-AMINO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES
    Publication number: 20170101391
    Abstract: Compounds of formula (I) which are inhibitors of Bub1 kinase, processes for their production and their use as pharmaceuticals.
    Type: Application
    Filed: June 17, 2015
    Publication date: April 13, 2017
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Keith GRAHAM, Ulrich KLAR, Hans BRIEM, Marion HITCHCOCK, Lars BÄRFACKER, Knut EIS, Volker SCHULZE, Gerhard SIEMEISTER, Wilhelm BONE, Jens SCHRÖDER, Simon HOLTON, Philip LIENAU, René TEMPEL, Helmut SONNENSCHEIN, Jozsef BÁLINT, Heinz GRAUBAUM
  • Substituted 4-aminocyclohexane derivatives
    Patent number: 9580386
    Abstract: The invention relates to compounds that have an affinity to the ?-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.
    Type: Grant
    Filed: August 14, 2014
    Date of Patent: February 28, 2017
    Assignee: GRÜNENTHAL
    Inventors: Bert Nolte, Wolfgang Schröder, Klaus Linz, Werner Englberger, Hans Schick, Heinz Graubaum, Birgit Braun, Sigrid Ozegowski, József Bálint, Helmut Sonnenschein
  • Substituted 4-aminocyclohexane derivatives
    Patent number: 9403767
    Abstract: The invention relates to compounds that have an affinity to the ?-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: August 2, 2016
    Assignee: GRUENENTHAL GMBH
    Inventors: Bert Nolte, Wolfgang Schröder, Klaus Linz, Werner Englberger, Hans Schick, Heinz Graubaum, Birgit Braun, Sigrid Ozegowski, József Bálint, Helmut Sonnenschein
  • Process for Preparing Spirocyclic Cyclohexane Compounds, Compositions Containing Such Compounds and Method of Using Such Compounds
    Publication number: 20150322080
    Abstract: Spirocyclic cyclohexane compounds corresponding to formula I a method for producing them, pharmaceutical compositions containing them, and methods of using them.
    Type: Application
    Filed: July 21, 2015
    Publication date: November 12, 2015
    Inventors: Claudia HINZE, Otto AULENBACHER, Bernd SUNDERMANN, Stefan OBERBOERSCH, Elmar FRIDERICHS, Werner ENGLBERGER, Babette-Yvonne KOEGEL, Klaus LINZ, Hans SCHICK, Helmut SONNENSCHEIN, Birgitta HENKEL, Valerie Sarah ROSE, Michael Jonathan LIPKIN
  • Process for preparing spirocyclic cyclohexane compounds, compositions containing such compounds and method of using such compounds
    Patent number: 9120797
    Abstract: Spirocyclic cyclohexane compounds corresponding to formula I a method for producing them, pharmaceutical compositions containing them, and methods of using them.
    Type: Grant
    Filed: September 2, 2011
    Date of Patent: September 1, 2015
    Assignee: Gruenenthal GmbH
    Inventors: Claudia Hinze, Otto Aulenbacher, Bernd Sundermann, Stefan Oberboersch, Elmar Friderichs, Werner Englberger, Babette-Yvonne Koegel, Klaus Linz, Hans Schick, Helmut Sonnenschein, Birgitta Henkel, Valerie Sarah Rose, Michael Jonathan Lipkin
  • SUBSTITUTED 4-AMINOCYCLOHEXANE DERIVATIVES
    Publication number: 20140357634
    Abstract: The invention relates to compounds that have an affinity to the ?-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.
    Type: Application
    Filed: August 14, 2014
    Publication date: December 4, 2014
    Applicant: GRÜNENTHAL GMBH
    Inventors: BERT NOLTE, WOLFGANG SCHRÖDER, KLAUS LINZ, WERNER ENGLBERGER, HANS SCHICK, HEINZ GRAUBAUM, BIRGIT ROLOFF, SIGRID OZEGOWSKI, JÓZSEF BÁLINT, HELMUT SONNENSCHEIN
  • Substituted 4-aminocyclohexane derivatives
    Patent number: 8835689
    Abstract: The invention relates to compounds that have an affinity to the ?-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.
    Type: Grant
    Filed: April 24, 2012
    Date of Patent: September 16, 2014
    Assignee: Grünenthal GmbH
    Inventors: Bert Nolte, Wolfgang Schröder, Klaus Linz, Werner Englberger, Hans Schick, Heinz Graubaum, Birgit Roloff, Sigrid Ozegowski, József Bálint, Helmut Sonnenschein
  • Substituted spiro compounds and their use for producing pain-relief medicaments
    Patent number: 8772307
    Abstract: The present invention relates to substituted spiro compounds, to processes for preparing them, to medicaments comprising these compounds and to the use of these compounds for producing medicaments.
    Type: Grant
    Filed: May 17, 2006
    Date of Patent: July 8, 2014
    Assignee: Gruenenthal GmbH
    Inventors: Robert Frank, Melanie Reich, Ruth Jostock, Gregor Bahrenberg, Hans Schick, Birgitta Henkel, Helmut Sonnenschein
  • Substituted cyclohexyldiamines
    Patent number: 8357705
    Abstract: The invention relates to compounds that have an affinity to the ?-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain or other conditions.
    Type: Grant
    Filed: March 25, 2009
    Date of Patent: January 22, 2013
    Assignee: Gruenenthal GmbH
    Inventors: Saskia Zemolka, Bert Nolte, Klaus Linz, Derek John Saunders, Wolfgang Schröder, Werner Englberger, Fritz Theil, Hans Schick, Jens Kaufmann, Julian Gebauer, Helmut Sonnenschein
  • Substituted spirocyclic cyclohexane derivatives
    Patent number: 8293758
    Abstract: The invention relates to compounds that have an affinity to the ?-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.
    Type: Grant
    Filed: March 25, 2009
    Date of Patent: October 23, 2012
    Assignee: Grunenthal GmbH
    Inventors: Saskia Zemolka, Bert Nolte, Sven Frormann, Claudia Hinze, Klaus Linz, Wolfgang Schröder, Werner Englberger, Hans Schick, Helmut Sonnenschein
  • SUBSTITUTED 4-AMINOCYCLOHEXANE DERIVATIVES
    Publication number: 20120202810
    Abstract: The invention relates to compounds that have an affinity to the ?-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.
    Type: Application
    Filed: April 24, 2012
    Publication date: August 9, 2012
    Applicant: Grunenthal GmbH
    Inventors: Bert NOLTE, Wolfgang SHRÖDER, Klaus LINZ, Werner ENGLBERGER, Hans SCHICK, Heinz GRAUBAUM, Birgit ROLOFF, Sigrid OZEGOWSKI, József BÁLINT, Helmut SONNENSCHEIN
  • Substituted cyclic urea derivatives and the use thereof as vanilloid receptor 1 modulators
    Patent number: 8207182
    Abstract: The present invention relates to substituted cyclic urea derivatives corresponding to formula I, to processes for the preparation thereof, to medicinal drugs containing such compounds, to the use of such compounds in the preparation of medicinal drugs and in related treatment methods.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: June 26, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Robert Frank, Bernd Sundermann, Hans Schick, Helmut Sonnenschein
  • Salts of substituted allophanates and their use in drugs
    Patent number: 8173700
    Abstract: The present invention relates to salts of substituted allophanates, methods for their production, medicaments containing said compounds and the use of said compound for the production of medicaments.
    Type: Grant
    Filed: May 17, 2006
    Date of Patent: May 8, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Robert Frank, Ruth Jostock, Hans Schick, Fritz Theil, Olga Groeger, Rene Kudick, Helmut Sonnenschein, Birgitta Henkel
  • Substituted heteroaryl derivatives
    Patent number: 8138187
    Abstract: The invention relates to substituted heteroaryl derivatives, to methods for the production thereof, to medicaments containing said compounds and to the use of substituted heteroaryl derivatives for producing medicaments.
    Type: Grant
    Filed: January 15, 2009
    Date of Patent: March 20, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Saskia Zemolka, Stefan Schunk, Werner Englberger, Babette-Yvonne Kögel, Klaus Linz, Hans Schick, Helmut Sonnenschein, Heinz Graubaum, Claudia Hinze
  • Process for Preparing Spirocyclic Cyclohexane Compounds, Compositions Containing Such Compounds and Method of Using Such Compounds
    Publication number: 20110319440
    Abstract: Spirocyclic cyclohexane compounds corresponding to formula I a method for producing them, pharmaceutical compositions containing them, and methods of using them.
    Type: Application
    Filed: September 2, 2011
    Publication date: December 29, 2011
    Applicant: GRUENENTHAL GmbH
    Inventors: Claudia HINZE, Otto Aulenbacher, Bernd Sundermann, Stefan Oberboersch, Elmar Friderichs, Werner Englberger, Babette-Yvonne Koegel, Klaus Linz, Hans Schick, Helmut Sonnenschein, Birgitta Henkel, Valerie Sarah Rose, Michael Jonathan Lipkin
  • Compositions containing spirocyclic cyclohexane compounds
    Patent number: 8053576
    Abstract: Spirocyclic cyclohexane compounds corresponding to formula I a method for producing them, pharmaceutical compositions containing them, and methods of using them.
    Type: Grant
    Filed: February 17, 2009
    Date of Patent: November 8, 2011
    Assignee: Gruenenthal GmbH
    Inventors: Claudia Hinze, Otto Aulenbacher, Bernd Sundermann, Stefan Oberboersch, Elmar Friderichs, Werner Englberger, Babette-Yvonne Koegel, Klaus Linz, Hans Schick, Helmut Sonnenschein, Birgitta Henkel, Valerie Sarah Rose, Michael Jonathan Lipkin
  • Substituted spiro-compounds and the use thereof for producing medicaments
    Patent number: 7981883
    Abstract: The present invention relates to substituted spiro compounds, to processes for preparing them, to medicaments comprising these compounds and to the use of these compounds for producing medicaments.
    Type: Grant
    Filed: May 17, 2006
    Date of Patent: July 19, 2011
    Assignee: Gruenenthal GmbH
    Inventors: Robert Frank, Ruth Jostock, Melanie Reich, Gregor Bahrenberg, Hans Schick, Helmut Sonnenschein
  • (Hetero)aryl cyclohexane derivatives
    Patent number: 7977370
    Abstract: The invention relates to compounds that have an affinity to the ?-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.
    Type: Grant
    Filed: March 25, 2009
    Date of Patent: July 12, 2011
    Assignee: Gruenenthal GmbH
    Inventors: Saskia Zemolka, Stefan Schunk, Bert Nolte, Klaus Linz, Wolfgang Schröder, Werner Englberger, Hans Schick, Helmut Sonnenschein, Birgitta Henkel, József Bálint