Abstract: Pharmaceutical compositions containing as an active ingredient a compound of the formula ##STR1## wherein n is 4 or 5, or a non-toxic, pharmacologically acceptable acid addition salt thereof; and a method of using the same as .beta.-adrenergic receptor blockers.

Abstract: Pharmaceutical compositions containing as an active ingredient a racemic or optically active compound of the formula ##STR1## wherein R.sub.1 is --(CH.sub.2).sub.X --CN, where X is 0, 1, 2 or 3,R.sub.2 is hydrogen, halogen or --NH--CO--NHR, where R is lower alkyl,R.sub.4 is alkyl of 1 to 3 carbon atoms, andR.sub.5 is alkyl of 1 to 3 carbon atoms or, together with R.sub.4, --(CH.sub.2).sub.p -- where p is 4, 5 or 6,Or a physiologically compatible acid addition salt thereof; and a method of using the same as adrenolytics and hypotensives.

Abstract: Racemic and optically active compounds of the formula ##STR1## wherein R.sub.1 is hydrogen; halogen; nitro; alkyl of 1 to 5 carbon atoms; alkoxy of 1 to 4 carbon atoms; alkenyl of 2 to 5 carbon atoms; alkynyl of 2 to 5 carbon atoms; alkylamino of 1 to 5 carbon atoms; dialkylamino of 1 to 5 carbon atoms in each alkyl; alkoxyalkyl of 2 to 6 carbon atoms; alkylamino-alkyl of 2 to 6 carbon atoms; dialkylaminoalkyl of 3 to 12 carbon atoms; --(CH.sub.2).sub.x --NH.sub.2, --(CH.sub.2).sub.x -- OH, all where x is an integer from 0 to 3; --COOH; --COOR.sub.6, where R.sub.6 is alkyl of 1 to 4 carbon atoms; alkynyloxy of 3 to 6 carbon atoms; alkenyloxy of 3 to 6 carbon atoms; --CO--R.sub.9, --OCO--R.sub.9, --NH--CO--R.sub.9, all where R.sub.9 is alkyl of 1 to 6 carbon atoms, phenylalkyl of 7 to 10 carbon atoms or phenyl; cycloalkyl of 3 to 7 carbon atoms; --Q--CO--NR.sub.7 R.sub.8, where Q is a single bond, oxygen, --NH--, -- CH.sub.2 -- or --CH.sub.2 --NH--, and R.sub.7 and R.sub.

Abstract: Compounds of the formula ##STR1## wherein R is secondary butyl or tertiary butyl, and their non-toxic, pharmacologically acceptable acid addition salts; the compounds as well as their salts are useful as .beta.-adrenergic receptor blocking agents and hypotensives.

Abstract: Pharmaceutical compositions containing as an active ingredient a compound of the formula ##STR1## wherein R, R.sub.1 and R.sub.2 are each hydrogen, fluorine, chlorine, bromine, methyl, ethyl, methoxy, trifluoromethyl or cyano, andR.sub.5 is hydrogen, methyl or ethyl, or a non-toxic, pharmaceutically acceptable acid addition salt thereof; and a method of using the same as analgesics and hypotensives.

Abstract: Pharmaceutical compositions containing as an active ingredient a compound of the formula ##EQU1## wherein R.sub.1 is --(CH.sub.2).sub.x --CN, where x is 0,1,2 or 3,R.sub.2 is hydrogen, halogen, alkyl of 1 to 5 carbon atoms, alkoxy of 1 to 5 carbon atoms, alkenyl of 2 to 5 carbon atoms or alkenyloxy of 2 to 5 carbon atoms;R.sub.3 is hydrogen, halogen, alkyl of 1 to 5 carbon atoms or alkoxy of 1 to 5 carbon atoms;R.sub.2 and R.sub.3, together with each other and the carbon atoms to which they are attached, form a saturated or unsaturated carbocyclic ring of up to 6 carbon atoms;R.sub.4 is hydrogen, alkyl of 1 to 5 carbon atoms or aralkyl; andn is an integer from 1 to 10, inclusive; or a non-toxic, pharmacologically acceptable acid addition salt thereof; and a method of using the same as .beta.-adrenergic receptor blockers and hypotensives.

Abstract: Compounds of the formula ##EQU1## wherein R.sub.1 is allyl, allyloxy or chlorine, R.sub.2 is hydrogen or methyl,R.sub.3 is hydrogen, alkyl of 1 to 5 carbon atoms or benzyl, andn is an integer from 2 to 6, inclusive,Provided, however, that when R.sub.1 is allyl or allyloxy, R.sub.2 is hydrogen; and their non-toxic, pharmacologically acceptable acid addition salts; the compounds as well as their salts are useful as .beta.-adrenergic blocking agents and hypotensives.

Abstract: Racemic or optically active compounds of the formula ##EQU1## wherein R.sub.1 is hydrogen, halogen, alkyl or 1 to 4 carbon atoms or alkoxy of 1 to 4 carbon atoms, andR.sub.2 is straight or branched hydroxyalkyl of 3 to 6 carbon atoms,And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as the salts are useful .beta.-adrenergic receptor blocking agents and hypotensives.

Abstract: Compounds of the formula ##EQU1## wherein R is hydrogen or alkyl of 1 to 3 carbon atoms, andR.sub.1 is hydrogen or methyl,And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as anticonvulsives and antiarrhythmics in warmblooded animals.

Abstract: Pharmaceutical compositions containing, as an active ingredient, a compound of the formula ##SPC1##WhereinR.sub.1 is phenyl or mono-, di or tri-substituted phenyl, the substituents being each halogen, methyl, methoxy or trifluoromethyl, andR.sub.2 is hydrogen, phenyl or halo-phenyl;And a method of using the same as antidepressants.

Abstract: 2-Phenylamino-imidazolines-(2) of the formula ##SPC1##Wherein R, R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen, fluorine, chlorine, bromine, methyl, ethyl, methoxy, trifluoromethyl and cyano and one of R.sub.3 and R.sub.4 being hydrogen while the other is ##EQU1## and R.sub.5 is selected from the group consisting of hydrogen, methyl and ethyl and their non-toxic, pharmaceutically acceptable acid addition salts which have analgesic and blood pressure reducing properties and their preparation.

Abstract: Compounds of the formula ##EQU1## wherein n is 4 or 5, and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as .beta.-adrenergic receptor blocking agents.