Patents by Inventor Helmut Vieweg

Helmut Vieweg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Urokinase inhibitors
    Patent number: 7745441
    Abstract: New urokinase inhibitors having a triisopropylphenylsulfonyl residue as an N?-substituent for 3-amidinophenylalanine are provided. The introduction of the triisopropylphenylsulfonyl residue greatly increases the affinity of the compounds to urokinase and, thereby, increases their inhibitory activity against urokinase. These urokinase inhibitors are useful in determining the role of urokinase and urokinase receptor in various diseases, particularly in tumor propagation and metastasis. Methods of treating tumors and a pharmaceutical composition are also provided.
    Type: Grant
    Filed: September 18, 1998
    Date of Patent: June 29, 2010
    Assignee: Wilex AG
    Inventors: Peter Wikström, Helmut Vieweg, Jörg Stürzebecher
  • Piperazides of substituted phenylalanine derivatives as thrombin inhibitors
    Patent number: 5607937
    Abstract: The present invention relates to D,L-, L- and D-phenylalanine piperazides of formula (I) defined in claim 1 that inhibit blood coagulation, and thrombin and/or trypsin, respectively. The compounds are extraordinarily absorbable after oral, intraduodenal and in particular rectal administration and show only a low toxicity.
    Type: Grant
    Filed: January 5, 1995
    Date of Patent: March 4, 1997
    Assignee: Pentapharm AG
    Inventors: Joerg Stuerzebecher, Helmut Vieweg, Peter Wikstroem, Christoph Adler
  • Meta-substituted phenylalanine derivatives
    Patent number: 5518735
    Abstract: D,L-, L- and D-phenyl alanine derivatives of formula (I) defined in claim 1 in which R.sub.1 is an amidino-, guanidino-, oxamidino-, aminomethyl- or amino group have been discovered which effectively prevent blood coagulation or thrombosis. The antithrombotically active compounds have low toxicity and may be administered by mouth, subcutaneously or intravenously.
    Type: Grant
    Filed: February 10, 1993
    Date of Patent: May 21, 1996
    Assignee: Pentapharm AG
    Inventors: Jorg Sturzebecher, Helmut Vieweg, Peter Wikstroem
  • 3-(mercaptoalkyl)quinazoline
    Patent number: 5306721
    Abstract: A compound or its tautomer of Formula I, ##STR1## wherein R.sup.1 is hydrogen, a 6-methyl, 6-fluoro, 6-chloro, 6-bromo, or 6,7-dimethoxy residue,R.sup.2 is hydrogen, or a methyl residue,and n is 1 or 2,and tautomers and their pharmaceutically acceptable alkali, or ammonium salts.
    Type: Grant
    Filed: August 2, 1993
    Date of Patent: April 26, 1994
    Assignee: Arzneimittelerk Dresden G.m.b.H.
    Inventors: Siegfried Leistner, Michael Gutschow, Karl Drossler, Helmut Vieweg, Gunther Wagner, Thomas Strohscheidt, Dieter Lohmann, Gunter Laban, Herwart Ambrosius, Angela Siegling