Patents by Inventor Helmut Zarbl

Helmut Zarbl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel Method of Cancer Diagnosis and Prognosis and Prediction of Response to Therapy
    Publication number: 20140295416
    Abstract: The invention relates to pharmaceutical compositions comprising of FRY polypeptides and nucleotides, methods to treat cancer, methods to diagnose cancer, and methods to determine the effectiveness of the treatment of cancer, as well as methods to differentiate stem cells.
    Type: Application
    Filed: December 6, 2011
    Publication date: October 2, 2014
    Applicant: University of Medicine and Dentistry of New Jersey
    Inventors: Helmut Zarbl, Jessica Graham
  • Method of identifying nucleic acid compositions for muting expression of a gene
    Publication number: 20050282764
    Abstract: The invention provides compositions and methods for muting expression of an endogenous gene in an animal cell, the muting resulting from providing a muting nucleic acid to a cell. The muting nucleic acid comprises a transgene, which is substantially homologous to a portion of the endogenous gene. The portion of the endogenous gene provided on the transgene can be from the 5?-untranscribed end, from the 3? untranscribed end, from an exon or an intron in the coding portion, or from a portion that overlaps any of these portions. Methods are provided for obtaining muting nucleic acid, and for screening for molecules that can mute the gene, and for molecules that can alleviate muting of the gene.
    Type: Application
    Filed: January 24, 2005
    Publication date: December 22, 2005
    Inventors: Mohammad Bahramian, Helmut Zarbl
  • Method of using nucleic acid compositions for muting expression of a gene in animals
    Publication number: 20050234003
    Abstract: The invention provides compositions and methods for muting expression of an endogenous gene in an animal, the muting resulting from providing a muting nucleic acid to cells in the animal. The muting nucleic acid comprises a transgene, which is substantially homologous to a portion of the endogenous gene. The portion of the endogenous gene provided on the transgene can be from the 5?-untranscribed end, from the 3? untranscribed end, from an exon or an intron in the coding portion, or from a portion that overlaps any of these portions.
    Type: Application
    Filed: January 24, 2005
    Publication date: October 20, 2005
    Inventors: Mohammad Bahramian, Helmut Zarbl
  • Muting gene activity using a transgenic nucleic acid
    Patent number: 6939712
    Abstract: The invention provides compositions and methods for muting expression of an endogenous gene in an animal cell, the muting resulting from providing a transgene to a cell. Expression of which transgene is undetectable. The transgene comprises the muting nucleic acid, which is substantially homologous to a portion of the endogenous gene. The portion of the endogenous gene provided on the transgene can be from the 5?-untranscribed end, from the 3? untranscribed end, from an exon or an intron in the coding portion, or from a portion that overlaps any of these portions. Methods are provided for obtaining muting nucleic acid, and for screening for molecules that can mute the gene, and for molecules that can alleviate muting of the gene.
    Type: Grant
    Filed: December 27, 1999
    Date of Patent: September 6, 2005
    Assignee: Impedagen, LLC
    Inventors: Mohammad B. Bahramian, Helmut Zarbl