Patents by Inventor Hema Masarapu

Hema Masarapu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TYMOVIRUS VIRUS AND VIRUS-LIKE PARTICLES AS NANOCARRIERS FOR IMAGING AND THERAPEUTIC AGENTS
    Publication number: 20240093160
    Abstract: A method of targeting cancer tissue in a subject includes administering to the subject a plurality of functionalized Tymovirus virus or virus-like particles loaded with or conjugated to an imaging agent, a therapeutic agent or a targeting agent.
    Type: Application
    Filed: August 29, 2023
    Publication date: March 21, 2024
    Inventors: Nicole F. Steinmetz, Hema Masarapu, He Hu
  • Tymovirus virus and virus-like particles as nanocarriers for imaging and therapeutic agents
    Patent number: 11739301
    Abstract: A method of targeting cancer tissue in a subject includes administering to the subject a plurality of functionalized Tymovirus virus or virus-like particles loaded with or conjugated to an imaging agent, a therapeutic agent or a targeting agent.
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: August 29, 2023
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Nicole F. Steinmetz, Hema Masarapu, He Hu
  • TYMOVIRUS VIRUS AND VIRUS-LIKE PARTICLES AS NANOCARRIERS FOR IMAGING AND THERAPEUTIC AGENTS
    Publication number: 20200283738
    Abstract: A method of targeting cancer tissue in a subject includes administering to the subject a plurality of functionalized Tymovirus virus or virus-like particles loaded with or conjugated to an imaging agent, a therapeutic agent or a targeting agent.
    Type: Application
    Filed: October 29, 2018
    Publication date: September 10, 2020
    Inventors: Nicole F. Steinmetz, Hema Masarapu, He Hu
  • Chimeric tymovirus-like particles and process thereof
    Patent number: 7815913
    Abstract: The present disclosure relates to chimeric tymovirus-like particles (TVLPs) comprising a fusion protein that further comprises of a first protein that is a truncated tymovirus coat protein and a second protein. These chimeric TVLPs are useful as antigens. The present disclosure provides a highly efficient means for differentiating Foot and Mouth Disease Virus (FMDV) infected animals from vaccinated animals. The present disclosure further provides a process for the production of chimeric TVLPs and a diagnostic kit for the determination of specific antibodies of FMDV to differentiate FMDV infected from vaccinated animals. The present disclosure also provides the use of the chimeric TVLPs for diagnostic purposes.
    Type: Grant
    Filed: September 16, 2008
    Date of Patent: October 19, 2010
    Assignee: Indian Immunologicals Limited
    Inventors: Hema Masarapu, Singanallur Balasubramanian Nagendrakumar, Dorairajan Thiagarajan, Villuppanoor Alwar Srinivasan
  • Chimeric Tymovirus-like Particles and Process Thereof
    Publication number: 20090087861
    Abstract: The present disclosure relates to chimeric tymovirus-like particles (TVLPs) comprising a fusion protein that further comprises of a first protein that is a truncated tymovirus coat protein and a second protein. These chimeric TVLPs are useful as antigens. The present disclosure provides a highly efficient means for differentiating Foot and Mouth Disease Virus (FMDV) infected animals from vaccinated animals. The present disclosure further provides a process for the production of chimeric TVLPs and a diagnostic kit for the determination of specific antibodies of FMDV to differentiate FMDV infected from vaccinated animals. The present disclosure also provides the use of the chimeric TVLPs for diagnostic purposes.
    Type: Application
    Filed: September 16, 2008
    Publication date: April 2, 2009
    Applicant: Indian Immunologicals Limited
    Inventors: Hema Masarapu, Singanallur Balasubramanian Nagendrakumar, Dorairajan Thiagarajan, Villuppanoor Alwar Srinivasan