Abstract: Systems and methods for use in the implementation and/or operation of quantum information processing (QIP) systems or quantum computers, and more particularly, to benchmark-driven automation for tuning quantum computers are described. A method includes identifying a set of quantum gates and a number of experimental shots to perform a benchmark algorithm for active stabilization of one or more observables of the set of quantum gates and executing the benchmarking algorithm based on the set of quantum gates and the number of experimental shots. Moreover, in response to the benchmarking algorithm being successful, executing an algorithm on the quantum computer, and in response to the benchmarking algorithm being unsuccessful, iterating the benchmarking algorithm by adjusting the set of quantum gates until the benchmarking algorithm is successful or a preset number of iterations is reached.