Patents by Inventor Hendricus Renerus Jacobus Mattheusq Hoogenboom

Hendricus Renerus Jacobus Mattheusq Hoogenboom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR OBTAINING POLYPEPTIDE CONSTRUCTS COMPRISING TWO OR MORE SINGLE DOMAIN ANTIBODIES
    Publication number: 20110028695
    Abstract: The present invention relates to methods for obtaining a polypeptide construct directed against one or more antigens and/or epitopes and having one or more desired characteristics, wherein the polypeptide construct comprises at least two single domain antibodies. The methods of the present invention involve producing a diversity of polypeptide constructs that are structural variants and screening the produced diversity of polypeptide constructs for a polypeptide construct having said one or more desired characteristics. The present invention further relates to polypeptide constructs directed against one or more antigens and/or epitopes having one or more desired characteristics, wherein the polypeptide construct comprises at least two single domain antibodies. The methods and polypeptide constructs according to the present invention are useful for the identification of optimal therapeutic compounds.
    Type: Application
    Filed: November 28, 2008
    Publication date: February 3, 2011
    Inventors: Hilde Adi Pierrette Revets, Hendricus Renerus Jacobus Mattheusq Hoogenboom