Patents by Inventor Hendrik Bart Van Den Berg Van Saparoea

Hendrik Bart Van Den Berg Van Saparoea has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DECORATED INCLUSION BODY AND USES THEREOF
    Publication number: 20220064691
    Abstract: The present disclosure relates in general to the field of inclusion bodies. Provided are inclusion bodies comprising a coupling peptide suitable for coupling to a partner peptide through the formation of a covalent isopeptide bond, as well as the use of different ligation systems for enabling efficient and stable decoration of inclusion bodies with, for example, biologically functional molecules to improve the use of inclusion bodies in biotechnology and biomedicine.
    Type: Application
    Filed: February 14, 2020
    Publication date: March 3, 2022
    Inventors: Joen LUIRINK, Wouter Simon Petrus Jong, Hendrik Bart VAN DEN BERG VAN SAPAROEA
  • Display of heterologous molecules on bacterial cells and membrane vesicles
    Patent number: 11059868
    Abstract: The present invention concerns Gram-negative bacterial cells or Outer Membrane Vesicles (OMVs) which display on their outer surface an autotransporter (AT) fusion protein covalently coupled via an isopeptide bond to a heterologous molecule. These bacterial cells and OMVs are suitable for use in vaccines or targeted drug delivery of antigens or therapeutic agents to specific cells or tissues.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: July 13, 2021
    Inventors: Hendrik Bart Van Den Berg Van Saparoea, Wouter Simon Petrus Jong, Joen Luirink
  • DISPLAY OF HETEROLOGOUS MOLECULES ON BACTERIAL CELLS AND MEMBRANE VESICLES
    Publication number: 20200377556
    Abstract: The present invention concerns Gram-negative bacterial cells or Outer Membrane Vesicles (OMVs) which display on their outer surface an autotransporter (AT) fusion protein covalently coupled via an isopeptide bond to a heterologous molecule. These bacterial cells and OMVs are suitable for use in vaccines or targeted drug delivery of antigens or therapeutic agents to specific cells or tissues.
    Type: Application
    Filed: October 25, 2018
    Publication date: December 3, 2020
    Applicant: ABERA BIOSCIENCE AB
    Inventors: Hendrik Bart Van Den Berg Van Saparoea, Wouter Simon Petrus Jong, Joen Luirink