Patents by Inventor Hendrik Schlehahn

Hendrik Schlehahn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TABLET CONTAINING VALSARTAN AND SACUBITRIL
    Publication number: 20230346709
    Abstract: The present invention relates to a tablet for oral administration containing valsartan and sacubitril, preferably as sodium salts or as a complex of valsartan disodium and sacubitril monosodium, preferably LCZ696. The tablet is prepared by dry-granulation or direct compression and contains a mesoporous inorganic stabilizer, e.g. mesoporous silica (Syloid®).
    Type: Application
    Filed: April 25, 2023
    Publication date: November 2, 2023
    Applicant: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Bala Ramesha Chary RALLABANDI, Vamshi Ramana PRATHAP, Krishna Mohan GOLLAPUDI, Bala Subramanian VELUSAMY, Srimannarayana BANDLA, Hendrik SCHLEHAHN, Dieter RUCHATZ
  • Gastro-resistant formulation containing posaconazole
    Patent number: 11590127
    Abstract: The present invention relates to a gastro-resistant pharmaceutical composition comprising a solid solution prepared by hot-melt extrusion, whereby the solid solution contains posaconazole, an enteric polymer and a non-enteric polymer. The composition is preferably a granulate material that can be filled into a capsule or compressed into a tablet.
    Type: Grant
    Filed: June 2, 2021
    Date of Patent: February 28, 2023
    Assignee: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Vamshi Ramana Prathap, Venkatasimhadri Naidu Kalamata, Bala Ramesha Chary Rallabandi, Vinay Kumar Katakam, Hendrik Schlehahn
  • STABLE HOT-MELT EXTRUDATE CONTAINING VALSARTAN AND SACUBITRIL
    Publication number: 20220226247
    Abstract: The present invention relates to a solid unit dosage form for oral administration (tablet or granules) containing a solid dispersion of valsartan and sacubitril in a polymeric matrix. The solid dispersion is prepared by hot-melt extrusion and may contain the active ingredients preferably in a non-crystalline state. LCZ696, (pseudo)polymorphic forms thereof as well as the individual drugs, e.g. valsartan disodium and sacubitril monosodium, may be subjected to the hot-melt extrusion process.
    Type: Application
    Filed: April 7, 2022
    Publication date: July 21, 2022
    Applicant: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Bala Ramesha Chary RALLABANDI, Vamshi Ramana PRATHAP, Rajesh Krishna Mohan GOLLAPUDI, Hendrik SCHLEHAHN, Dieter RUCHATZ
  • GASTRO-RESISTANT FORMULATION CONTAINING POSACONAZOLE
    Publication number: 20210283130
    Abstract: The present invention relates to a gastro-resistant pharmaceutical composition comprising a solid solution prepared by hot-melt extrusion, whereby the solid solution contains posaconazole, an enteric polymer and a non-enteric polymer. The composition is preferably a granulate material that can be filled into a capsule or compressed into a tablet.
    Type: Application
    Filed: June 2, 2021
    Publication date: September 16, 2021
    Applicant: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Vamshi Ramana PRATHAP, Venkatasimhadri Naidu KALAMATA, Bala Ramesha Chary RALLABANDI, Vinay Kumar KATAKAM, Hendrik SCHLEHAHN
  • Gastro-resistant formulation containing posaconazole
    Patent number: 11058682
    Abstract: The present invention relates to a gastro-resistant pharmaceutical composition comprising a solid solution prepared by hot-melt extrusion, whereby the solid solution contains posaconazole, an enteric polymer and a non-enteric polymer. The composition is preferably a granulate material that can be filled into a capsule or compressed into a tablet.
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: July 13, 2021
    Assignee: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Vamshi Ramana Prathap, Venkatasimhadri Naidu Kalamata, Bala Ramesha Chary Rallabandi, Vinay Kumar Katakam, Hendrik Schlehahn
  • STABLE HOT-MELT EXTRUDATE CONTAINING VALSARTAN AND SACUBITRIL
    Publication number: 20210085610
    Abstract: The present invention relates to a solid unit dosage form for oral administration (tablet or granules) containing a solid dispersion of valsartan and sacubitril in a polymeric matrix. The solid dispersion is prepared by hot-melt extrusion and may contain the active ingredients preferably in a non-crystalline state. LCZ696, (pseudo)polymorphic forms thereof as well as the individual drugs, e.g. valsartan disodium and sacubitril monosodium, may be subjected to the hot-melt extrusion process.
    Type: Application
    Filed: March 29, 2018
    Publication date: March 25, 2021
    Applicant: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Bala Ramesha Chary RALLABANDI, Vamshi Ramana PRATHAP, Rajesh Krishna Mohan GOLLAPUDI, Hendrik SCHLEHAHN, Dieter RUCHATZ
  • TABLET CONTAINING VALSARTAN AND SACUBITRIL
    Publication number: 20200276129
    Abstract: The present invention relates to a tablet for oral administration containing valsartan and sacubitril, preferably as sodium salts or as a complex of valsartan disodium and sacubitril monosodium, preferably LCZ696. The tablet is prepared by dry-granulation or direct compression and contains a mesoporous inorganic stabilizer, e.g. mesoporous silica (Syloid®).
    Type: Application
    Filed: October 12, 2018
    Publication date: September 3, 2020
    Applicant: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Bala Ramesha Chary RALLABANDI, Vamshi Ramana PRATHAP, Krishna Mohan GOLLAPUDI, Bala Subramanian VELUSAMY, Srimannarayana BANDLA, Hendrik SCHLEHAHN, Dieter RUCHATZ
  • PIRFENIDONE-CONTAINING TABLET AND CAPSULE FORMULATION
    Publication number: 20190216738
    Abstract: The present invention relates to granules containing pirfenidone and a sugar alcohol, and, furthermore, to the use of the granules for the preparation of an immediate-release tablet or capsule.
    Type: Application
    Filed: November 6, 2018
    Publication date: July 18, 2019
    Inventors: Chaitanya Yogananda Gujjar, Susheel Prakash Uppala, Harish Dhanala, Nani Prasad Donga, Srimannarayana Bandla, Bala Ramesha Chary Rallabandi, Siva Rama Krishna Velaga, Hendrik Schlehahn
  • GASTRO-RESISTANT FORMULATION CONTAINING POSACONAZOLE
    Publication number: 20180228798
    Abstract: The present invention relates to a gastro-resistant pharmaceutical composition comprising a solid solution prepared by hot-melt extrusion, whereby the solid solution contains posaconazole, an enteric polymer and a non-enteric polymer. The composition is preferably a granulate material that can be filled into a capsule or compressed into a tablet.
    Type: Application
    Filed: July 21, 2016
    Publication date: August 16, 2018
    Applicant: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Vamshi Ramana PRATHAP, Venkatasimhadri Naidu KALAMATA, Bala Ramesha Chary RALLABANDI, Vinay Kumar KATAKAM, Hendrik SCHLEHAHN
  • Pharmaceutical formulation comprising levothyroxine sodium
    Patent number: 7955621
    Abstract: There is provided a stable pharmaceutical formulation comprising (a) an effective amount of levothyroxine sodium, (b) microcrystalline cellulose which has a mean particle size of less than 125 ?m and is present in an amount of 60 to 85% w/w based upon the total weight of the formulation, and (c) pregelatinised starch present in an amount of 5 to 30% w/w based upon total weight of the formulation. There is also provided a process for the preparation of such a formulation.
    Type: Grant
    Filed: July 8, 2004
    Date of Patent: June 7, 2011
    Assignee: Aspen Global Incorporated
    Inventors: Malgorzata Konieczna, Heiner Krohn, Wanda Roman, Hendrik Schlehahn, Malgorzata Anna Strozyk