Patents by Inventor Heng-Liang Liu

Heng-Liang Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8980624
    Abstract: An apparatus for high-throughput cell culture with mechanical compression stimulation includes a cell culture vessel and a fluid pressure supply unit. The cell culture vessel includes at least one culture chamber, at least one pressure chamber disposed above the culture chamber, a membrane disposed between the culture chamber and the pressure chamber, and at least one pressurizing member that projects downwardly from the membrane into the culture chamber. The fluid pressure supply unit is connected fluidly to the pressure chamber, and has a fluid pressure supply device to supply a pressurized fluid to the pressure chamber so as to deform the membrane and move the pressurizing member, and a control device that is adapted to vary a pressure of the pressurized fluid in the pressure chamber.
    Type: Grant
    Filed: January 4, 2010
    Date of Patent: March 17, 2015
    Assignee: Chang Gung University
    Inventors: Min-Hsien Wu, Chun-Li Lin, Shiao-Wen Tsai, Heng-Liang Liu, Yen-Ting Liu
  • Patent number: 8366721
    Abstract: The primary objective of the present invention is to provide a positioning device for surgical operation, which could allow a surgical tool to be positioned precisely at a specific operating spot or a specific operating angle by providing a three axial free-moving function and a vertical and horizontal free-rotating function. Furthermore, the present invention is able to be electrically connected to and controlled by an automatic control system to achieve a more precise and efficient positioning function.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: February 5, 2013
    Assignee: Chang-Gung University
    Inventors: Shih-Tseng Lee, Wen-Yo Lee, Heng-Liang Liu
  • Patent number: 8352056
    Abstract: The present invention illustrates a method of manufacturing a surgical implant guide to increase the precision, safety and reliability of the surgery. First the present invention plans an invasive position for implanting an implant, and then, plans an invasive path for the implant to invade from the invasive position of an affected tissue, and finally, produces an implant guide based on the invasive position, the invasive path, and the shapes of the implant and the affected tissue. The surgical implant guide includes a coupling portion matching the shape the affected tissue, and a guiding portion matching the shape of the implant, the invasive position, and the invasive path. When the coupling portion is disposed on the affected tissue, the guiding portion is aligned with the invasive position, so that the implant is implanted in the affected tissue under guidance of the invasive path.
    Type: Grant
    Filed: February 8, 2010
    Date of Patent: January 8, 2013
    Assignee: Chang-Gung University
    Inventors: Shih-Tsen Lee, Chieh-Tsai Wu, Heng-Liang Liu, Ming-Yuan Tsai
  • Patent number: 8298245
    Abstract: A three-dimensional positioning device for minimally invasive surgery includes a base, two angle adjustable assemblies, an arc, a sliding assembly, a first positioning assembly, a second positioning assembly and a third positioning assembly. The base includes two first frames and two second frames. Two ends of each second frame are connected to the first frames respectively. Each first frame has a pivotal member. The angle adjustable assemblies are pivotably connected to the pivotal member of the first frame respectively. The arc includes a hollow track member. The angle adjustable assemblies are connected to two ends of the arc. The sliding assembly is mounted on the track member of the arc according to a predetermined position of a nidus. Therefore, the three-dimensional positioning device can effectively improve precision and operation more precisely in minimally invasive surgery to increase surgery success rate.
    Type: Grant
    Filed: August 17, 2009
    Date of Patent: October 30, 2012
    Assignee: Chang Gung University
    Inventors: Shih-Tseng Li, Yau-Zen Chang, Heng-Liang Liu, Shun-Chung Chuang
  • Publication number: 20110282355
    Abstract: The primary objective of the present invention is to provide a positioning device for surgical operation, which could allow a surgical tool to be positioned precisely at a specific operating spot or a specific operating angle by providing a three axial free-moving function and a vertical and horizontal free-rotating function. Furthermore, the present invention is able to be electrically connected to and controlled by an automatic control system to achieve a more precise and efficient positioning function.
    Type: Application
    Filed: August 4, 2010
    Publication date: November 17, 2011
    Applicant: CHANG-GUNG UNIVERSITY
    Inventors: Shih-Tseng LEE, Wen-Yo LEE, Heng-Liang LIU
  • Publication number: 20110093023
    Abstract: The present invention illustrates a method of manufacturing a surgical implant guide to increase the precision, safety and reliability of the surgery. First the present invention plans an invasive position for implanting an implant, and then, plans an invasive path for the implant to invade from the invasive position of an affected tissue, and finally, produces an implant guide based on the invasive position, the invasive path, and the shapes of the implant and the affected tissue. The surgical implant guide includes a coupling portion matching the shape the affected tissue, and a guiding portion matching the shape of the implant, the invasive position, and the invasive path. When the coupling portion is disposed on the affected tissue, the guiding portion is aligned with the invasive position, so that the implant is implanted in the affected tissue under guidance of the invasive path.
    Type: Application
    Filed: February 8, 2010
    Publication date: April 21, 2011
    Applicant: CHANG-GUNG UNIVERSITY
    Inventors: Shih-Tseng Lee, Chieh-Tsai Wu, Heng-Liang Liu, Ming-Yuan Tsai
  • Publication number: 20110076758
    Abstract: An apparatus for high-throughput cell culture with mechanical compression stimulation includes a cell culture vessel and a fluid pressure supply unit. The cell culture vessel includes at least one culture chamber, at least one pressure chamber disposed above the culture chamber, a membrane disposed between the culture chamber and the pressure chamber, and at least one pressurizing member that projects downwardly from the membrane into the culture chamber. The fluid pressure supply unit is connected fluidly to the pressure chamber, and has a fluid pressure supply device to supply a pressurized fluid to the pressure chamber so as to deform the membrane and move the pressurizing member, and a control device that is adapted to vary a pressure of the pressurized fluid in the pressure chamber.
    Type: Application
    Filed: January 4, 2010
    Publication date: March 31, 2011
    Inventors: Min-Hsien Wu, Chun-Li Lin, Shiao-Wen Tsai, Heng-Liang Liu, Yen-Ting Liu
  • Publication number: 20110040304
    Abstract: A three-dimensional positioning device for minimally invasive surgery comprising: a base, two angle adjustable assemblies, an arc, a sliding assembly, a first positioning assembly, a second positioning assembly and a third positioning assembly. The base includes two first frames and two second frames. Two ends of each second frame connected to the first frames respectively. Each first frame has a pivotal member. The angle adjustable assemblies are pivotably connected to the pivotal member of the first frame respectively. The arc includes a hollow track member. The angle adjustable assemblies are connected to two ends of the arc. The sliding assembly is mounted on the track member of the arc according to a predetermined position of a nidus. Therefore, the three-dimensional positioning device can effectively improve the precision and operate more precisely in the minimally invasive surgery to increase the surgery success rate.
    Type: Application
    Filed: August 17, 2009
    Publication date: February 17, 2011
    Inventors: Shih-Tseng Li, Yau-Zen Chang, Heng-Liang Liu, Shun-Chung Chuang