Patents by Inventor Hengchu Cao
Hengchu Cao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180318075Abstract: Disclosed prosthetic valves can comprise a sewing ring configured to secure the valve to an implantation site. Some disclosed valves comprise a resiliently collapsible frame having a neutral configuration and a collapsed deployment configuration. Some disclosed frames can self-expand to the neutral configuration when released from the collapsed deployment configuration. Collapsing a disclosed valve can provide convenient access to the sewing ring, such as for securing the valve to the implantation site, as well as for the insertion of the valve through relatively small surgical incisions.Type: ApplicationFiled: May 25, 2018Publication date: November 8, 2018Inventors: Hengchu Cao, Brian S. Conklin, Paul A. Schmidt, Grace M. Kim, James A. Davidson, Hoa T. Tran, Kristy L. Tam
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Publication number: 20180296326Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. The clasps each have a fixed arm and a plurality of moveable arms each having a barbed portion. A plurality of hinge portions connect the moveable arms to the fixed arm.Type: ApplicationFiled: March 1, 2018Publication date: October 18, 2018Applicant: Edwards Lifesciences CorporationInventors: Eric Robert Dixon, Jensen Chen, Guillermo W. Moratorio, Hengchu Cao, Douglas Thomas Dominick, Sergio Delgado, Lauren R. Freschauf
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Publication number: 20180296334Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles have an outer portion and an inner portion. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the plurality of paddles. The clasps have a concave upper surface and a convex lower surface. The clasps include a fixed arm attached to the inner portion of the paddle, a moveable arm having a barbed portion, and a hinge portion connecting the fixed arm to the moveable arm.Type: ApplicationFiled: April 13, 2018Publication date: October 18, 2018Inventors: Eric Robert Dixon, Jensen Chen, Guillermo W. Moratorio, Hengchu Cao, Douglas Thomas Dominick, Sergio Delgado, Lauren R. Freschauf
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Publication number: 20180296333Abstract: An implantable prosthetic device has a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the paddles. The clasps comprise a fixed arm attached and a plurality of moveable arms each having a barbed portion. A plurality of hinge portions connect the fixed arm to the plurality of moveable arms.Type: ApplicationFiled: April 13, 2018Publication date: October 18, 2018Inventors: Eric Robert Dixon, Jensen Chen, Guillermo W. Moratorio, Hengchu Cao, Douglas Thomas Dominick, Sergio Delgado, Lauren R. Freschauf
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Publication number: 20180296331Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the paddles. Each clasp has a fixed arm attached to the paddle and a moveable arm having a barbed portion. A hinge portion connects the fixed arm to the moveable arm. The device does not include catch points when the paddles are in the open position and the clasps are in a closed condition.Type: ApplicationFiled: April 5, 2018Publication date: October 18, 2018Inventors: Eric Robert Dixon, Jensen Chen, Guillermo W. Moratorio, Hengchu Cao, Douglas Thomas Dominick, Sergio Delgado, Lauren R. Freschauf
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Publication number: 20180296329Abstract: An implantable prosthetic has a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp has a fixed arm attached to the paddle. The clasps also have a moveable arm having a barbed portion and an end that is rounded. A hinge portion connects the fixed arm to the moveable arm.Type: ApplicationFiled: March 7, 2018Publication date: October 18, 2018Applicant: Edwards Lifesciences CorporationInventors: Eric Robert Dixon, Jensen Chen, Guillermo W. Moratorio, Hengchu Cao, Douglas Thomas Dominick, Sergio Delgado, Lauren R. Freschauf
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Publication number: 20180296332Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the paddles. Each clasp has a fixed arm attached to the inner portion of the paddle and a moveable arm having a barbed portion. A hinge portion connects the fixed arm to the moveable arm. A cover wraps around at least a portion of the moveable arm of the clasp. At least one actuation suture is attached to the cover.Type: ApplicationFiled: April 13, 2018Publication date: October 18, 2018Inventors: Eric Robert Dixon, Jensen Chen, Guillermo W. Moratorio, Hengchu Cao, Douglas Thomas Dominick, Sergio Delgado, Lauren R. Freschauf
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Publication number: 20180296328Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the paddles. The clasps have a fixed arm attached to the paddle and a moveable arm. The moveable arm has a barbed portion, a first eyelet, and a second eyelet. The hinge portion connects the fixed arm to the moveable arm. A first intermediate suture loop is attached to the first eyelet and a second intermediate suture loop is attached to the second eyelet. At least one actuation suture is attached to the first and second intermediate suture loops.Type: ApplicationFiled: March 2, 2018Publication date: October 18, 2018Applicant: Edwards Lifesciences CorporationInventors: Eric Robert Dixon, Jensen Chen, Guillermo W. Moratorio, Hengchu Cao, Douglas Thomas Dominick, Sergio Delgado, Lauren R. Freschauf
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Publication number: 20180296330Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles having an outer portion and inner portion. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the paddles. The clasps have a fixed arm attached to the inner portion of the paddle and a hoop-shaped moveable arm having a barbed portion. A hinge portion connects the fixed arm to the moveable arm.Type: ApplicationFiled: March 21, 2018Publication date: October 18, 2018Inventors: Eric Robert Dixon, Jensen Chen, Guillermo W. Moratorio, Hengchu Cao, Douglas Thomas Dominick, Sergio Delgado, Lauren R. Freschauf
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Publication number: 20180296327Abstract: An implantable prosthetic device such as might be used to treat poor function of a diseased heart valve in a medical patient includes a body portion and an anchor portion including a plurality of paddles. Clasps attached to the paddles include fixed arms and moveable arms operable to secure the device to the patient's native valve leaflets.Type: ApplicationFiled: January 30, 2018Publication date: October 18, 2018Applicant: Edwards Lifesciences CorporationInventors: Eric Robert Dixon, Jensen Chen, Guillermo W. Moratorio, Hengchu Cao, Douglas Thomas Dominick, Sergio Delgado, Lauren R. Freschauf
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Publication number: 20180185154Abstract: In one embodiment, a leaflet capture device for improving the coaptation of heart valve leaflets is provided. The leaflet capture device can include a first clip portion having inner and outer portions. The inner and outer portions can be configured to compress tissue of a first heart valve leaflet therebetween to secure the first clip portion to the first leaflet. The leaflet capture device can further include a second clip portion having inner and outer portions. The inner and outer portions can be configured to compress tissue of a second heart valve leaflet therebetween to secure the second clip portion to the second leaflet. The first and second clip portions can be separately deployable onto the first and second leaflets and secured to one another in vivo to bring portions of the first and second leaflets into closer proximity to each other, thereby improving coaptation of the first and second leaflets.Type: ApplicationFiled: December 15, 2017Publication date: July 5, 2018Applicant: Edwards Lifesciences CorporationInventor: Hengchu Cao
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Patent number: 9980816Abstract: Disclosed prosthetic valves can comprise a sewing ring configured to secure the valve to an implantation site. Some disclosed valves comprise a resiliently collapsible frame having a neutral configuration and a collapsed deployment configuration. Some disclosed frames can self-expand to the neutral configuration when released from the collapsed deployment configuration. Collapsing a disclosed valve can provide convenient access to the sewing ring, such as for securing the valve to the implantation site, as well as for the insertion of the valve through relatively small surgical incisions. Examples of delivery systems and methods for deploying the valves exhibit reduced patient trauma.Type: GrantFiled: March 19, 2015Date of Patent: May 29, 2018Assignee: Edwards Lifesciences CorporationInventors: Hengchu Cao, Brian S. Conklin, Paul A. Schmidt, Grace M. Kim, James A. Davidson, Hoa T. Tran, Kristy L. Tam
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Publication number: 20170119523Abstract: A low pressure gradient prosthetic heart valve for implant in a human. The valve includes a support frame with undulating inflow cusps and outflow commissure posts to which flexible leaflets attach and coapt in a flow area. The commissure posts angle outward in a neutral state to widen the outflow orifice area. Also, the leaflets are designed to fit within the support frame and expand outward in a valve open state without creating a shelf or belly that would restrict flow.Type: ApplicationFiled: January 11, 2017Publication date: May 4, 2017Inventors: Hengchu Cao, Wei Sun
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Patent number: 9554901Abstract: A low pressure gradient prosthetic heart valve for implant in a human. The valve includes a support frame with undulating inflow cusps and outflow commissure posts to which flexible leaflets attach and coapt in a flow area. The commissure posts angle outward in a neutral state to widen the outflow orifice area. Also, the leaflets are designed to fit within the support frame and expand outward in a valve open state without creating a shelf or belly that would restrict flow.Type: GrantFiled: May 11, 2011Date of Patent: January 31, 2017Assignee: Edwards Lifesciences CorporationInventors: Hengchu Cao, Wei Sun
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Patent number: 9498202Abstract: Disclosed herein are exemplary embodiments of suture securement devices that replace the need to tie knots in sutures. Some embodiments comprise an annular outer body and one or more suture engagement tabs extending inwardly from the outer body. The devices can comprise a superelastic and/or shape-memory material and have a generally in-plane initial configuration. The suture engagement portions are deformable out-of-plane to an active configuration with the outer body compressed and the tabs interlocked with each other. The device can be heat-set in the deformed configuration. The interlocked tabs exert a pinching force on sutures passing between them that restricts the sutures from sliding through the opening in one longitudinal direction.Type: GrantFiled: July 9, 2013Date of Patent: November 22, 2016Assignee: Edwards Lifesciences CorporationInventors: Mohammad Jafari, Ming H. Wu, Hengchu Cao, Ralph Schneider, Manouchehr A. Miraki
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Publication number: 20160270776Abstract: Some disclosed suture securement devices comprise a flat, thin, generally planar body that has one or more suture engagement slots extending into the body from a perimeter inlet for receiving sutures laterally into the device. The slots can be resiliently widened to receive a suture and then released to clamp onto the suture. Some embodiments include two or more such suture engagement slots that independently receive and secure different sutures. Some embodiments include one or more locking tabs that have a closed position that retains the slots against widening and blocks the inlet to the slot. In some embodiment two or more slots are position next to each other on the same side of the device, while in other embodiments slots are positioned on opposite sides of the device. Other types of suture securement devices are also disclosed.Type: ApplicationFiled: March 8, 2016Publication date: September 22, 2016Applicant: Edwards Lifesciences CorporationInventors: Manouchehr A. Miraki, Hengchu Cao, Ralph Schneider
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Publication number: 20160166248Abstract: A multiple-fire securing device includes a hollow outer shaft, a reloader, a reloader movement assembly, a rail, and securing structures each defining an inner securing orifice. The reloader longitudinally moves within the outer shaft and has a distal end shaped to temporarily contact one of the securing structures. The rail is disposed within the reloader and has an installing location. The securing structures are disposed on the rail. The reloader movement assembly moves the reloader longitudinally in a distal direction to deliver a first securing structure to the installing location from a first proximal position and moves the reloader proximally away from the installing location without the first securing structure to a position in which the distal end of the reloader temporarily contacts a second one of the securing structures. The second and successive securing structures are moved one at a time to the installing location.Type: ApplicationFiled: December 10, 2015Publication date: June 16, 2016Inventors: Derek Dee Deville, Kevin W. Smith, Michael Walter Kirk, Carlos Rivera, George Nunez, Thomas O. Bales, JR., Korey Kline, Matthew A. Palmer, M. Sean McBrayer, Richard Cartledge, Max Pierre Mendez, Hengchu Cao, Anthony Peter Carcia, Kevin Dang, Carey Hendsbee, Brent K. Hoffman, Brian R. Jacobs, Mohammad Jafari, Brian Janish, Jeffrey L. Mahoney, Raffaele Mazzei, Manouchehr A. Miraki, Ryan Moehle, Jeremiah Morgan, Michael C. Murad, Travis Zenyo Oba, Ralph Schneider, Fabian Daniel Schroeder, Tyler Douglas Smith, Ming H. Wu
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Publication number: 20150230922Abstract: Disclosed prosthetic valves can comprise a sewing ring configured to secure the valve to an implantation site. Some disclosed valves comprise a resiliently collapsible frame having a neutral configuration and a collapsed deployment configuration. Some disclosed frames can self-expand to the neutral configuration when released from the collapsed deployment configuration. Collapsing a disclosed valve can provide convenient access to the sewing ring, such as for securing the valve to the implantation site, as well as for the insertion of the valve through relatively small surgical incisions. Examples of delivery systems and methods for deploying the valves exhibit reduced patient trauma.Type: ApplicationFiled: March 19, 2015Publication date: August 20, 2015Inventors: Hengchu Cao, Brian S. Conklin, Paul A. Schmidt, Grace M. Kim, James A. Davidson, Hoa T. Tran, Kristy L. Tam
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Patent number: 8986374Abstract: Disclosed prosthetic valves can comprise a sewing ring configured to secure the valve to an implantation site. Some disclosed valves comprise a resiliently collapsible frame having a neutral configuration and a collapsed deployment configuration. Some disclosed frames can self-expand to the neutral configuration when released from the collapsed deployment configuration. Collapsing a disclosed valve can provide convenient access to the sewing ring, such as for securing the valve to the implantation site, as well as for the insertion of the valve through relatively small surgical incisions.Type: GrantFiled: May 10, 2011Date of Patent: March 24, 2015Assignee: Edwards Lifesciences CorporationInventors: Hengchu Cao, Brian Conklin, Paul Schmidt, Grace Myong Kim, James A. Davidson, Hoa Trinh Tran, Kristy Luong Tam
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Publication number: 20140031864Abstract: Disclosed herein are exemplary embodiments of suture securement devices that replace the need to tie knots in sutures. Some embodiments comprise an annular outer body and one or more suture engagement tabs extending inwardly from the outer body. The devices can comprise a superelastic and/or shape-memory material and have a generally in-plane initial configuration. The suture engagement portions are deformable out-of-plane to an active configuration with the outer body compressed and the tabs interlocked with each other. The device can be heat-set in the deformed configuration. The interlocked tabs exert a pinching force on sutures passing between them that restricts the sutures from sliding through the opening in one longitudinal direction.Type: ApplicationFiled: July 9, 2013Publication date: January 30, 2014Inventors: Mohammad Jafari, Ming H. Wu, Hengchu Cao, Ralph Schneider