Abstract: An HP spherical deformation diagnosis model and a construction method thereof are provided. The HP spherical deformation diagnosis model is used for identifying whether HP spherical deformation exists in an IHC dyeing image of an HP positive gastric mucosal sample, and includes: an image processing module and an identification module; the image processing module comprises a contrast enhancement module, an image filtering module, and an HP dyeing extraction module; the contrast enhancement module comprises: an HIS color model transformation module, which is used for transforming an original image from an RGB color model to an HIS color model in which hue, saturation, and intensity are separated; and a piecewise linear transformation module, which is used for enhancing a grayscale region of interest in the image by using a piecewise linear transformation method for a brightness component in the HIS color module, so as to improve the image.

Abstract: An HP spherical deformation diagnosis model and a construction method thereof are provided. The HP spherical deformation diagnosis model is used for identifying whether HP spherical deformation exists in an IHC dyeing image of an HP positive gastric mucosal sample, and includes: an image processing module and an identification module; the image processing module comprises a contrast enhancement module, an image filtering module, and an HP dyeing extraction module; the contrast enhancement module comprises: an HIS color model transformation module, which is used for transforming an original image from an RGB color model to an HIS color model in which hue, saturation, and intensity are separated; and a piecewise linear transformation module, which is used for enhancing a grayscale region of interest in the image by using a piecewise linear transformation method for a brightness component in the HIS color module, so as to improve the image.

Abstract: An antigen and kit for the detection of a Helicobacter pylori antibody, and a preparation method thereof are provided. The kit includes an antigen for the detection of the Helicobacter pylori antibody, the antigen is Helicobacter pylori HpC-025 with the deposit registration number of CCTCC No: M20221024, and the detection object of the kit is oral exudate. The antigen is a natural antigen and has a sensitivity superior to the sensitivities of the natural antigen of Hp international standard strain 11637, the natural antigen of Hp-Ag from the Japanese Institute of Immunology and the recombinant antigen of Hp-Ag. The kit has no significant requirements for usage scenarios, can be used in medical institutions at all levels or at home, and can be used for household screening of Helicobacter pylori.