Patents by Inventor Hengrui LIU

Hengrui LIU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GPX4 COMPOUNDS AND COMPOSITIONS AND METHODS OF TREATMENT USING SAME
    Publication number: 20230167058
    Abstract: The present disclosure provides, inter alia, compounds to modulate GPX4 activity. Also provided are pharmaceutical compositions containing same compounds. Further provided are methods for treating or ameliorating the effects of a cancer in a subject, methods of modulating GPX activity in a subject, methods of inducing ferroptosis in a cell, and methods for treating or ameliorating the effects of a cancer in a subject using the compounds or composition in combination with other therapeutic agents.
    Type: Application
    Filed: September 12, 2022
    Publication date: June 1, 2023
    Inventors: Brent R. STOCKWELL, Hengrui LIU, Farhad FOROUHAR, Qian WANG