Abstract: Disclosed herein are methods and compositions related to determining one or more biomarkers in Full-Length Excised Linear Intron RNAs (FLEXI RNAs) and Intron RNA fragments. These FLEXI RNAs and Intron RNA fragments can be indicative of a specific characteristic. trait. disease. disorder or condition. FLEXI RNAs and Intron RNA fragments can be used to establish a predictive bio-marker. a diagnostic biomarker, a prognostic biomarker, or a biomarker that relates to drug interaction, drug response, or to a heritable condition. These biomarkers can then be used to treat. monitor. or inform patients.

Abstract: A shift register unit includes a shift circuit having first, second, and third power supply signal terminals respectively coupled to first, second, and third power supply lines configured respectively to transmit first, second, and third power supply signals; and configured to respond to the first or second power supply signal and output the signal from a first node to an output terminal; a signal generating circuit respectively coupled to the first and second power supply lines and the first node, and configured to output the second power supply signal to the first node when an electric potential of the first power supply signal is an effective potential, and output the first power supply signal to the first node when the electric potential of the second power supply signal is an effective potential, wherein the electric potentials of the first and second power supply signals are complementary to each other.

Abstract: The present disclosure provides a mask plate, a method for forming a via-hole, a method for forming a display substrate, the display substrate, and a display device. The mask plate is configured to form the via-hole in a layer, and includes a transparent pattern for the formation of the via-hole. The transparent pattern includes one or more curved edge, so the via-hole formed using the mask plate is provided with one or more curved edges at its bottom.

Abstract: A shift register unit includes a shift circuit having first, second, and third power supply signal terminals respectively coupled to first, second, and third power supply lines configured respectively to transmit first, second, and third power supply signals; and configured to respond to the first or second power supply signal and output the signal from a first node to an output terminal; a signal generating circuit respectively coupled to the first and second power supply lines and the first node, and configured to output the second power supply signal to the first node when an electric potential of the first power supply signal is an effective potential, and output the first power supply signal to the first node when the electric potential of the second power supply signal is an effective potential, wherein the electric potentials of the first and second power supply signals are complementary to each other.

Abstract: The present disclosure provides a mask plate, a method for forming a via-hole, a method for forming a display substrate, the display substrate, and a display device. The mask plate is configured to form the via-hole in a layer, and includes a transparent pattern for the formation of the via-hole. The transparent pattern includes one or more curved edge, so the via-hole formed using the mask plate is provided with one or more curved edges at its bottom.

Abstract: The present disclosure provides a pixel structure, a display panel and a fabrication method thereof, and a display device. The pixel structure includes a substrate and an inorganic photoluminescent layer formed on the substrate. The pixel structure incudes an excitation layer disposed on a side of the inorganic photoluminescent layer away from the substrate and configured to excite the inorganic photoluminescent layer to emit light. The pixel structure includes an organic light-emitting layer in the same layer as the excitation layer. A space is disposed between the organic light-emitting layer and the excitation layer. An orthographic projection of the excitation layer on the substrate overlaps at least partially an orthographic projection of the inorganic photoluminescent layer on the substrate.

Abstract: A pixel structure includes a plate electrode, an interlayer insulating layer and strip electrodes which are sequentially arranged on a substrate. The strip electrodes include first strip electrode(s), second strip electrode(s) and third strip electrode(s). The first strip electrode(s) and the plate electrode are oppositely arranged, so that an orthographic projection of the first strip electrode(s) on the substrate at least partially overlaps with an orthographic projection of the plate electrode on the substrate. The first strip electrode(s) and the plate electrode are configured to be applied with different voltages during display.

Abstract: A shift register unit including a first node control circuit, a second node control circuit, an energy-storing circuit, a first voltage pull circuit, a second voltage pull circuit, and an output circuit. The first node control circuit is configured to transfer a reset signal at a reset signal terminal to a first node in response to the reset signal at the reset signal terminal being active. The second node control circuit is configured to transfer an inactive voltage at a first voltage terminal to the first node in response to a potential at a second node being active. The output circuit is configured to transfer a clock signal at a clock signal terminal to a signal output terminal in response to the potential at the second node being active.

Abstract: A shift register unit including a first node control circuit, a second node control circuit, an energy-storing circuit, a first voltage pull circuit, a second voltage pull circuit, and an output circuit. The first node control circuit is configured to transfer a reset signal at a reset signal terminal to a first node in response to the reset signal at the reset signal terminal being active. The second node control circuit is configured to transfer an inactive voltage at a first voltage terminal to the first node in response to a potential at a second node being active. The output circuit is configured to transfer a clock signal at a clock signal terminal to a signal output terminal in response to the potential at the second node being active.

Abstract: The present disclosure provides a pixel structure, a display panel and a fabrication method thereof, and a display device. The pixel structure includes a substrate and an inorganic photoluminescent layer formed on the substrate. The pixel structure incudes an excitation layer disposed on a side of the inorganic photoluminescent layer away from the substrate and configured to excite the inorganic photoluminescent layer to emit light. The pixel structure includes an organic light-emitting layer in the same layer as the excitation layer. A space is disposed between the organic light-emitting layer and the excitation layer. An orthographic projection of the excitation layer on the substrate overlaps at least partially an orthographic projection of the inorganic photoluminescent layer on the substrate.

Abstract: A pixel structure includes a plate electrode, an interlayer insulating layer and strip electrodes which are sequentially arranged on a substrate. The strip electrodes include first strip electrode(s), second strip electrode(s) and third strip electrode(s). The first strip electrode(s) and the plate electrode are oppositely arranged, so that an orthographic projection of the first strip electrode(s) on the substrate at least partially overlaps with an orthographic projection of the plate electrode on the substrate. The first strip electrode(s) and the plate electrode are configured to be applied with different voltages during display.

Abstract: A nanoparticle-based delivery system and methods for its use are disclosed. In one aspect, a nanoparticle-based delivery system comprising at least one molecule such as proteins, DNA/RNA or fragments thereof, carbohydrates, enzymes, chemicals, virus cells, bacteria, parts of a virus, parts of a bacteria, parts of a cell, part of a tissue, or a combination of one or more of these, which shall be referred to as immunogens, are chemically or physically combined with water soluble nanoparticles which, when administered to a living system, is capable of eliciting a desired immunological response. More particularly, the invention relates to nanoparticle-based delivery systems that are specifically engineered to enhance humoral or cellular immune response without the use of adjuvants.