Patents by Inventor Hengyi Zhu

Hengyi Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • WEEDING DEVICE FOR CROPS HAVING SEEDLING AVOIDANCE FUNCTION
    Publication number: 20240081165
    Abstract: A weeding device for crops having a seedling avoidance function includes a rack connected to a weeding machine. A hydraulic pump and two hydraulic cylinders are mounted to the rack. Bottom ends of each of the two hydraulic cylinders are provided with a vertically arranged support rod. An inter-row weeder is mounted to a bottom end of each of the two support rods. A slider configured to reciprocate in a horizontal direction is positioned on two slide rails that are mounted to the rack. An inter-plant weeder is mounted to a bottom side of the slider. A plurality of weeder blades are arranged side by side on the inter-plant weeder. At the weeding position, an arrangement direction of weeder blades is perpendicular to an advancing direction, and at the weed avoidance position, the arrangement direction of the weeder blades is parallel to the advancing direction, thereby avoiding crops.
    Type: Application
    Filed: November 22, 2023
    Publication date: March 14, 2024
    Inventors: Xin JIN, Hengyi ZHANG, Hongbin SUO, Xiaowu ZHU, Mengnan LIU, Yirong ZHAO, Bo ZHAO
  • Double-stranded RNAS directed to IKK-2
    Patent number: 7759476
    Abstract: Compositions and methods are provided for treating NF-?B-related conditions. In particular, the invention provides a stimulus-inducible IKK signalsome, and components and variants thereof. An IKK signalsome or component thereof may be used, for example, to identify antibodies and other modulating agents that inhibit or activate signal transduction via the NF-?B cascade. IKK signalsome, components thereof and/or modulating agents may also be used for the treatment of diseases associated with NF-?B activation.
    Type: Grant
    Filed: October 22, 2007
    Date of Patent: July 20, 2010
    Assignee: Signal Pharmaceuticals
    Inventors: Frank Mercurio, Hengyi Zhu, Miguel Barbosa, Jian Wu Li, Brion W. Murray
  • Stimulus Inducible Protein Kinase Complex and Methods of Use Therefor
    Publication number: 20090169564
    Abstract: Compositions and methods are provided for treating NF-?B-related conditions. In particular, the invention provides a stimulus-inducible IKK signalsome, and components and variants thereof. An IKK signalsome or component thereof may be used, for example, to identify antibodies and other modulating agents that inhibit or activate signal transduction via the NF-?B cascade. IKK signalsome, components thereof and/or modulating agents may also be used for the treatment of diseases associated with NF-?B activation.
    Type: Application
    Filed: October 22, 2007
    Publication date: July 2, 2009
    Inventors: Frank Mercurio, Hengyi Zhu, Miguel Barbosa, Jian Wu Li, Brion W. Murray
  • THIAZOLE AND THIADIAZOLE INHIBITORS OF TYROSINE PHOSPHATASES
    Publication number: 20080200371
    Abstract: Compounds and compositions are provided for modulating the activity of protein tyrosine phosphatases. In one embodiment, the compounds and compositions are thiazoles and thiadiazoles that inhibit the activity of protein tyrosine phosphatase 1B.
    Type: Application
    Filed: March 28, 2008
    Publication date: August 21, 2008
    Inventors: Zacharia S. CHERUVALLATH, Colin J. Loweth, Ruth F. Nutt, Darryl Rideout, Joseph E. Semple, Jing Wang, Feiyue Wu, Shankari Mylvaganam, Hengyi Zhu, Jianzhong Sun
  • Thiazole and thiadiazole inhibitors of tyrosine phosphatases
    Patent number: 7381736
    Abstract: Compounds and compositions are provided for modulating the activity of protein tyrosine phosphatases. In one embodiment, the compounds and compositions are thiazoles and thiadiazoles that inhibit the activity of protein tyrosine phosphatase 1B.
    Type: Grant
    Filed: September 2, 2005
    Date of Patent: June 3, 2008
    Assignee: Metabasis Therapeutics, Inc.
    Inventors: Zacharia S. Cheruvallath, Colin J. Loweth, Ruth F. Nutt, Darryl Rideout, Joseph E. Semple, Jing Wang, Feiyue Wu, Shankari Mylvaganam, Hengyi Zhu, Jianzhong Sun
  • Stimulus-inducible protein kinase complex and methods of use therefor
    Patent number: 7285654
    Abstract: Compositions and methods are provided for treating NF-?B-related conditions. In particular, the invention provides a stimulus-inducible IKK signalsome, and components and variants thereof. An IKK signalsome or component thereof may be used, for example, to identify antibodies and other modulating agents that inhibit or activate signal transduction via the NF-?B cascade. IKK signalsome, components thereof and/or modulating agents may also be used for the treatment of diseases associated with NF-?B activation.
    Type: Grant
    Filed: January 8, 2003
    Date of Patent: October 23, 2007
    Assignee: Signal Pharmaceuticals
    Inventors: Frank Mercurio, Hengyi Zhu, Miguel Barbosa, Jian Wu Li, Brion W. Murray
  • Thiazole and thiadiazole inhibitors of tyrosine phosphatases
    Publication number: 20060194768
    Abstract: Compounds and compositions are provided for modulating the activity of protein tyrosine phosphatases. In one embodiment, the compounds and compositions are thiazoles and thiadiazoles that inhibit the activity of protein tyrosine phosphatase 1B.
    Type: Application
    Filed: September 2, 2005
    Publication date: August 31, 2006
    Inventors: Zacharia Cheruvallath, Colin Loweth, Ruth Nutt, Darryl Rideout, Joseph Semple, Jing Wang, Feiyue Wu, Shankari Mylvaganam, Hengyi Zhu, Jianzhong Sun
  • Stimulus-inducible protein kinase complex and methods of use therefor
    Patent number: 6576437
    Abstract: Compositions and methods are provided for treating NF-&kgr;B-related conditions. In particular, the invention provides a stimulus-inducible IKK signalsome, and components and variants thereof. An IKK signalsome or component thereof may be used, for example, to identify antibodies and other modulating agents that inhibit or activate signal transduction via the NF-&kgr;B cascade. IKK signalsome, components thereof and/or modulating agents may also be used for the treatment of diseases associated with NF-&kgr;B activation.
    Type: Grant
    Filed: April 27, 2001
    Date of Patent: June 10, 2003
    Assignee: Signal Pharmaceuticals, Inc.
    Inventors: Frank Mercurio, Hengyi Zhu, Miguel Barbosa, Jian Wu Li, Brion W. Murray
  • Stimulus-inducible protein kinase complex and methods of use therefor
    Publication number: 20030100026
    Abstract: Compositions and methods are provided for treating NF-&kgr;B-related conditions. In particular, the invention provides a stimulus-inducible IKK signalsome, and components and variants thereof. An IKK signalsome or component thereof may be used, for example, to identify antibodies and other modulating agents that inhibit or activate signal transduction via the NF-&kgr;B cascade. IKK signalsome, components thereof and/or modulating agents may also be used for the treatment of diseases associated with NF-&kgr;B activation.
    Type: Application
    Filed: January 8, 2003
    Publication date: May 29, 2003
    Inventors: Frank Mercurio, Hengyi Zhu, Miguel Barbosa, Jian Wu Li, Brion W. Murray
  • Stimulus-inducible protein kinase complex and methods of use therefor
    Publication number: 20020151021
    Abstract: Compositions and methods are provided for treating NF-&kgr;B-related conditions. In particular, the invention provides a stimulus-inducible IKK signalsome, and components and variants thereof. An IKK signalsome or component thereof may be used, for example, to identify antibodies and other modulating agents that inhibit or activate signal transduction via the NF-&kgr;B cascade. IKK signalsome, components thereof and/or modulating agents may also be used for the treatment of diseases associated with NF-&kgr;B activation.
    Type: Application
    Filed: April 27, 2001
    Publication date: October 17, 2002
    Inventors: Frank Mercurio, Hengyi Zhu, Miguel Barbosa, Jian Wu Li, Brion W. Murray
  • Stimulus-inducible protein kinase complex and methods of use therefor
    Patent number: 6258579
    Abstract: Compositions and methods are provided for treating NF-&kgr;B-related conditions. In particular, the invention provides a stimulus-inducible IKK signalsome, and components and variants thereof. An IKK signalsome or component thereof may be used, for example, to identify antibodies and other modulating agents that inhibit or activate signal transduction via the NF-&kgr;B cascade. IKK signalsome, components thereof and/or modulating agents may also be used for the treatment of diseases associated with NF-&kgr;B activation.
    Type: Grant
    Filed: August 13, 1997
    Date of Patent: July 10, 2001
    Assignee: Signal Pharmaceuticals, Inc.
    Inventors: Frank Mercurio, Hengyi Zhu, Miguel Barbosa, Jian Wu Li, Brion W. Murray
  • Stimulus-inducible protein kinase complex and methods of use therefor
    Patent number: 5972674
    Abstract: Compositions and methods are provided for treating NF-.kappa.B-related conditions. In particular, the invention provides a stimulus-inducible I.kappa.B.alpha. kinase complex, and components and variants thereof. I.kappa.B.alpha. kinase complex may be used, for example, to identify antibodies and other agents that inhibit or activate signal transduction via the NF-.kappa.B cascade. I.kappa.B.alpha. kinase complex, components thereof and/or such agents may also be used for the treatment of diseases associated with NF-.kappa.B activation.
    Type: Grant
    Filed: August 26, 1996
    Date of Patent: October 26, 1999
    Assignee: Signal Pharmaceuticals, Inc.
    Inventors: Frank Mercurio, Hengyi Zhu, Miguel Barbosa