Abstract: A method, system, and related computer program products for processing and displaying dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) information are described. A plurality of instances of an MRI volume of the body part acquired at a respective plurality of sample times subsequent to an administration of a tracer is processed to determine a plurality of pharmacokinetic (PK) parameters characterizing a mathematical model-based relationship between a plasma tracer concentration and a total tracer concentration within the body part. For one preferred embodiment, computation of the PK parameters is performed according to a generalized signal model such that computation can be carried out in real time during an interactive viewer session, with required reference regions being selectable and optionally re-selectable by the viewer without requiring extensive waiting times for PK parameter computation. Associated user interfaces and computer-aided detection (CAD) algorithms are also provided.

Abstract: A method, system, and related computer program products for processing and displaying dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) information are described. A plurality of instances of an MRI volume of the body part acquired at a respective plurality of sample times subsequent to an administration of a tracer is processed to determine a plurality of pharmacokinetic (PK) parameters characterizing a mathematical model-based relationship between a plasma tracer concentration and a total tracer concentration within the body part. For one preferred embodiment, computation of the PK parameters is performed according to a generalized signal model such that computation can be carried out in real time during an interactive viewer session, with required reference regions being selectable and optionally re-selectable by the viewer without requiring extensive waiting times for PK parameter computation. Associated user interfaces and computer-aided detection (CAD) algorithms are also provided.