Patents by Inventor Henning Gieseler

Henning Gieseler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240148726
    Abstract: The present invention relates to a freeze-dried (also called lyophilized) drug nanosuspension. The present freeze-dried drug nanosuspension composition has an acceptable stability of the particle size distribution during storage, including long term storage.
    Type: Application
    Filed: October 16, 2023
    Publication date: May 9, 2024
    Inventors: Sabine Karine Katrien Inghelbrecht, Jakob Andreas Beirowski, Henning Gieseler
  • Patent number: 11819502
    Abstract: The present invention relates to a freeze-dried (also called lyophilized) drug nanosuspension. The present freeze-dried drug nanosuspension composition has an acceptable stability of the particle size distribution during storage, including long term storage.
    Type: Grant
    Filed: June 6, 2022
    Date of Patent: November 21, 2023
    Assignee: Janssen Pharmaceutica NV
    Inventors: Sabine Karine Katrien Inghelbrecht, Jakob Andreas Beirowski, Henning Gieseler
  • Patent number: 11576863
    Abstract: The present invention provides a method for preparation of a lyophilized formulation of an anti-CD 20 antibody as well as to a lyophilized formulation of an anti-CD 20 antibody, comprising an anti-CD 20 antibody and having a residual moisture content in the range of 1% to 10%. The present invention also relates to the reconstituted formulation obtained by the method described herein, the use of said antibody formulation as a medicament, the use of the lyophilized formulation for the preparation of a medicament and a method of treating a patient.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: February 14, 2023
    Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Markus Rast, Wolfgang Ise, Gerhard Becker, Peter Skufca, Henning Gieseler
  • Publication number: 20220409616
    Abstract: The present invention relates to a freeze-dried (also called lyophilized) drug nanosuspension. The present freeze-dried drug nanosuspension composition has an acceptable stability of the particle size distribution during storage, including long term storage.
    Type: Application
    Filed: June 6, 2022
    Publication date: December 29, 2022
    Inventors: Sabine Karine Katrien Inghelbrecht, Jakob Andreas Beirowski, Henning Gieseler
  • Patent number: 11433029
    Abstract: The present invention provides a method for preparation of a lyophilized formulation of an anti-CD 20 antibody as well as to a lyophilized formulation of an anti-CD 20 antibody, comprising an anti-CD 20 antibody and having a residual moisture content in the range of 1% to 10%. The present invention also relates to the reconstituted formulation obtained by the method described herein, the use of said antibody formulation as a medicament, the use of the lyophilized formulation for the preparation of a medicament and a method of treating a patient.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: September 6, 2022
    Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Markus Rast, Wolfgang Ise, Gerhard Becker, Peter Skufca, Henning Gieseler
  • Patent number: 11389448
    Abstract: The present invention relates to a freeze-dried (also called lyophilized) drug nanosuspension. The present freeze-dried drug nanosuspension composition has an acceptable stability of the particle size distribution during storage, including long term storage.
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: July 19, 2022
    Assignee: Janssen Pharmaceutica NV
    Inventors: Sabine Karine Katrien Inghelbrecht, Jakob Andreas Beirowski, Henning Gieseler
  • Publication number: 20190076428
    Abstract: The present invention relates to a freeze-dried (also called lyophilized) drug nanosuspension. The present freeze-dried drug nanosuspension composition has an acceptable stability of the particle size distribution during storage, including long term storage.
    Type: Application
    Filed: November 8, 2018
    Publication date: March 14, 2019
    Inventors: Sabine Karine Katrien Inghelbrecht, Jakob Andreas Beirowski, Henning Gieseler
  • Patent number: 10166231
    Abstract: The present invention relates to a freeze-dried (also called lyophilized) drug nanosuspension. The present freeze-dried drug nanosuspension composition has an acceptable stability of the particle size distribution during storage, including long term storage.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: January 1, 2019
    Assignee: Janssen Pharmaceutica NV
    Inventors: Sabine Karine Katrien Inghelbrecht, Jakob Andreas Beirowski, Henning Gieseler
  • Publication number: 20160317534
    Abstract: The present invention relates to a freeze-dried (also called lyophilized) drug nanosuspension. The present freeze-dried drug nanosuspension composition has an acceptable stability of the particle size distribution during storage, including long term storage.
    Type: Application
    Filed: July 7, 2016
    Publication date: November 3, 2016
    Inventors: Sabine Karine Katrien Inghelbrecht, Jakob Andreas Beirowski, Henning Gieseler
  • Publication number: 20140038996
    Abstract: The present invention relates to a freeze-dried (also called lyophilized) drug nanosuspension. The present freeze-dried drug nanosuspension composition has an acceptable stability of the particle size distribution during storage, including long term storage.
    Type: Application
    Filed: April 13, 2012
    Publication date: February 6, 2014
    Applicant: Janssen Pharmaceutica NV
    Inventors: Sabine Karine Katrien Inghelbrecht, Jakob Andreas Beirowski, Henning Gieseler