Patents by Inventor Henning Groll

Henning Groll has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11561156
    Abstract: Devices and methods for the deposition of reagents onto cells or tissue samples are disclosed. Also disclosed are reagent compositions suitable for dispensing via a droplet-on-demand system.
    Type: Grant
    Filed: October 12, 2017
    Date of Patent: January 24, 2023
    Assignee: Ventana Medical Systems, Inc.
    Inventors: Henning Groll, Melis Hazar, Eric L. Klein, Raymond T. Kozikowski, III, Chana R. Paluszcyk, Melinda J. Polaske, Raviraj Thakur
  • Publication number: 20210223146
    Abstract: Methods and compositions for removing precipitates or reducing the formation of precipitates generated in hematoxylin solutions. The methods and compositions feature cleaning solutions that feature chemical compounds that initiate processes including but not limited to acidification of the waste solution, chelation of metal ions in the waste solution, reduction reactions, oxidation reactions, and metal salt addition reactions.
    Type: Application
    Filed: April 5, 2021
    Publication date: July 22, 2021
    Inventors: Edward E. Durrant, Henning Groll, Casey A. Kernag, Charles H. Weidner, Kenneth S. Weir
  • Patent number: 10976223
    Abstract: Methods and compositions for removing precipitates or reducing the formation of precipitates generated in hematoxylin solutions. The methods and compositions feature cleaning solutions that feature chemical compounds that initiate processes including but not limited to acidification of the waste solution, chelation of metal ions in the waste solution, reduction reactions, oxidation reactions, and metal salt addition reactions.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: April 13, 2021
    Assignee: Ventana Medical Systems, Inc.
    Inventors: Edward E. Durrant, Henning Groll, Casey A. Kernag, Charles H. Weidner, Kenneth S. Weir
  • Publication number: 20210080360
    Abstract: Automated system configured to perform and methods for performing one or more slide processing operations on slides bearing biological samples. The system and methods enable high sample throughput while also minimizing or limiting the potential for cross-contamination of slides. The automated systems can include features that facilitate consistency, controllability of processing time, and/or processing temperature.
    Type: Application
    Filed: August 21, 2020
    Publication date: March 18, 2021
    Inventors: Kayla Capps, Henning Groll, Brian Howard Kram, Matthew Mette, Ali Mousavi, Christine Tse, Glen Ward, Daniel O'Connor, Troy Paluszcyk, Benjamin David Randall, Ken Stumpe
  • Patent number: 10794805
    Abstract: Automated system configured to perform and methods for performing one or more slide processing operations on slides bearing biological samples. The system and methods enable high sample throughput while also minimizing or limiting the potential for cross-contamination of slides. The automated systems can include features that facilitate consistency, controllability of processing time, and/or processing temperature.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: October 6, 2020
    Assignee: Ventana Medical Systems, Inc.
    Inventors: Kayla Capps, Henning Groll, Brian Howard Kram, Matthew Mette, Ali Mousavi, Christine Tse, Glen Ward, Daniel O'Connor, Troy Paluszcyk, Benjamin David Randall, Ken Stumpe
  • Patent number: 10509216
    Abstract: A specimen processing system is capable of processing specimens carried on slides. The specimen processing system can sequentially deliver slides and opposables to specimen processing stations. The specimen processing stations can use the opposables to apply a series of liquids to the specimens. The applied liquid can be moved along the slide using capillary action while the specimen processing stations control the processing temperatures.
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: December 17, 2019
    Assignee: VENTANA MEDICAL SYSTEMS, INC.
    Inventors: Brian Kram, Sacha Dopheide, Jessica Wifall, Kevin Marshall, Simon Spence, Andrew Watkins, Austin Ashby, Bryan Barnes, Henning Groll, Lizhen Pang, Patrick Brown, Mirek Holubec, Matthew Ketterer, Kevin Talucci, Benjamin James
  • Publication number: 20190234843
    Abstract: Automated system configured to perform and methods for performing one or more slide processing operations on slides bearing biological samples. The system and methods enable high sample throughput while also minimizing or limiting the potential for cross-contamination of slides. The automated systems can include features that facilitate consistency, controllability of processing time, and/or processing temperature.
    Type: Application
    Filed: April 5, 2019
    Publication date: August 1, 2019
    Inventors: Kayla Capps, Henning Groll, Brian Howard Kram, Matthew Mette, Ali Mousavi, Christine Tse, Glen Ward, Daniel O'Connor, Troy Paluszcyk, Benjamin David Randall, Ken Stumpe
  • Patent number: 10254202
    Abstract: Automated system configured to perform and methods for performing one or more slide processing operations on slides bearing biological samples. The system and methods enable high sample throughput while also minimizing or limiting the potential for cross-contamination of slides. The automated systems can include features that facilitate consistency, controllability of processing time, and/or processing temperature.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: April 9, 2019
    Assignee: Ventana Medical Systems, Inc.
    Inventors: Kayla Capps, Henning Groll, Brian Howard Kram, Matthew Mette, Ali Mousavi, Christine Tse, Glen Ward, Daniel O'Connor, Troy Paluszcyk, Benjamin David Randall, Ken Stumpe
  • Publication number: 20180172563
    Abstract: Methods and compositions for removing precipitates or reducing the formation of precipitates generated in hematoxylin solutions. The methods and compositions feature cleaning solutions that feature chemical compounds that initiate processes including but not limited to acidification of the waste solution, chelation of metal ions in the waste solution, reduction reactions, oxidation reactions, and metal salt addition reactions.
    Type: Application
    Filed: November 17, 2017
    Publication date: June 21, 2018
    Inventors: Edward E. Durrant, Henning Groll, Casey A. Kernag, Charles H. Weidner, Kenneth S. Weir
  • Publication number: 20180052082
    Abstract: Devices and methods for the deposition of reagents onto cells or tissue samples are disclosed. Also disclosed are reagent compositions suitable for dispensing via a droplet-on-demand system.
    Type: Application
    Filed: October 12, 2017
    Publication date: February 22, 2018
    Inventors: Henning Groll, Melis Hazar, Eric L. Klein, Raymond T. Kozikowski, III, Chana R. Paluszcyk, Melinda J. Polaske, Raviraj Thakur
  • Publication number: 20160282239
    Abstract: Automated system configured to perform and methods for performing one or more slide processing operations on slides bearing biological samples. The system and methods enable high sample throughput while also minimizing or limiting the potential for cross-contamination of slides. The automated systems can include features that facilitate consistency, controllability of processing time, and/or processing temperature.
    Type: Application
    Filed: June 10, 2016
    Publication date: September 29, 2016
    Inventors: Kayla Capps, Henning Groll, Brian Howard Kram, Matthew Mette, Ali Mousavi, Christine Tse, Glen Ward, Daniel O'Connor, Troy Paluszcyk, Benjamin David Randall, Ken Stumpe
  • Patent number: 9410915
    Abstract: The present invention provides a test strip for measuring a signal of interest in a biological fluid when the test strip is mated to an appropriate test meter, wherein the test strip and the test meter include structures to verify the integrity of the test strip traces, to measure the parasitic resistance of the test strip traces, and to provide compensation in the voltage applied to the test strip to account for parasitic resistive losses in the test strip traces.
    Type: Grant
    Filed: July 14, 2014
    Date of Patent: August 9, 2016
    Assignees: Roche Operations Ltd., Roche Diabetes Care, Inc.
    Inventors: Michael J. Celentano, Henning Groll, James L. Pauley, Steven K. Moore
  • Publication number: 20160042136
    Abstract: A blood glucose management device is disclosed that is operable to seamlessly and sequentially provide a sequence of at least two displays of data relating to one or more blood glucose measurements to a user, upon minimal user interaction with the blood glucose management device.
    Type: Application
    Filed: October 21, 2015
    Publication date: February 11, 2016
    Applicant: ROCHE DIABETES CARE, INC.
    Inventor: Henning Groll
  • Patent number: 9218453
    Abstract: A blood glucose management device is operable to seamlessly provide a sequence of at least two displays of data relating to one or more blood glucose measurements to a user, upon minimal user interaction, with the blood glucose management device.
    Type: Grant
    Filed: June 29, 2009
    Date of Patent: December 22, 2015
    Assignee: Roche Diabetes Care, Inc.
    Inventor: Henning Groll
  • Publication number: 20150293341
    Abstract: A specimen processing system is capable of processing specimens carried on slides. The specimen processing system can sequentially deliver slides and opposables to specimen processing stations. The specimen processing stations can use the opposables to apply a series of liquids to the specimens. The applied liquid can be moved along the slide using capillary action while the specimen processing stations control the processing temperatures.
    Type: Application
    Filed: June 18, 2015
    Publication date: October 15, 2015
    Inventors: Brian Kram, Sacha Dopheide, Jessica Wifall, Kevin Marshall, Simon Spence, Andrew Watkins, Austin Ashby, Bryan Barnes, Henning Groll, Lizhen Pang, Patrick Brown, Mirek Holubec, Matthew Ketterer, Kevin Talucci, Benjamin James
  • Publication number: 20140318991
    Abstract: The present invention provides a test strip for measuring a signal of interest in a biological fluid when the test strip is mated to an appropriate test meter, wherein the test strip and the test meter include structures to verify the integrity of the test strip traces, to measure the parasitic resistance of the test strip traces, and to provide compensation in the voltage applied to the test strip to account for parasitic resistive losses in the test strip traces.
    Type: Application
    Filed: July 14, 2014
    Publication date: October 30, 2014
    Applicants: ROCHE OPERATIONS LTD., ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Michael J. Celentano, Henning Groll, James L. Pauley, Steven K. Moore
  • Patent number: 8685229
    Abstract: The present invention provides a system of biosensors whose dose-response curves are maintained within a predetermined and desired range or tolerance during production by selecting a feature of the biosensors that can be varied during production. For example, in one exemplary embodiment the effective area of the working electrode of an electrochemical biosensor can be varied during production as needed to offset variations that occur, e.g., in the reagent of the biosensors as production proceeds. In another exemplary embodiment, the dose-response curve of biosensors not yet produced can be predicted and one or more features of these biosensors can be selected to maintain the dose-response curve within a predetermined range or tolerance.
    Type: Grant
    Filed: July 10, 2013
    Date of Patent: April 1, 2014
    Assignee: Roche Diagnostics Operations, Inc.
    Inventor: Henning Groll
  • Patent number: 8663442
    Abstract: A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the corrected DC response. Other methods and devices are disclosed.
    Type: Grant
    Filed: October 20, 2008
    Date of Patent: March 4, 2014
    Assignees: Roche Diagnostics Operations, Inc., Roche Operations Ltd.
    Inventors: David W. Burke, Nigel A. Surridge, Henning Groll
  • Publication number: 20140027279
    Abstract: The present invention provides a test strip for measuring a signal of interest in a biological fluid when the test strip is mated to an appropriate test meter, wherein the test strip and the test meter include structures to verify the integrity of the test strip traces, to measure the parasitic resistance of the test strip traces, and to provide compensation in the voltage applied to the test strip to account for parasitic resistive losses in the test strip traces.
    Type: Application
    Filed: January 24, 2013
    Publication date: January 30, 2014
    Inventors: Michael J. Celentano, Henning Groll, James L. Pauley, Steven K. Moore
  • Patent number: 8608937
    Abstract: The present invention provides a system of biosensors whose dose-response curves are maintained within a predetermined and desired range or tolerance during production by selecting a feature of the biosensors that can be varied during production. For example, in one exemplary embodiment the effective area of the working electrode of an electrochemical biosensor can be varied during production as needed to offset variations that occur, e.g., in the reagent of the biosensors as production proceeds. In another exemplary embodiment, the dose-response curve of biosensors not yet produced can be predicted and one or more features of these biosensors can be selected to maintain the dose-response curve within a predetermined range or tolerance.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: December 17, 2013
    Assignee: Roche Diagnostics Operations, Inc.
    Inventor: Henning Groll