Patents by Inventor Henri Desmolin

Henri Desmolin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microbeads of diltiazem, a process for their manufacture and a substained-release pharmaceutical composition containing them
    Patent number: 5344657
    Abstract: The microbeads are composed of a core containing the active ingredient and a microporous membrane, insoluble in aqueous medium, consisting of a film-forming polymer, a plasticizer and a filling material.The membrane has a thickness such that diltiazem is released in vitro at an approximately constant rate for at least 6 hours after a latent period of less than one hour.The active ingredient can be intimately mixed with the core or included in a polyvinyl pyrrolidone layer coating an inert grain.The sustained-release microbeads are formed by application to the core of a dispersion of the constituents of the membrane in a solvent and evaporation of the solvent.The pharmaceutical compositions consist of capsules containing the microbeads. They are administered orally one or twice per day, depending on the dose, for the treatment of angina or hypertension.
    Type: Grant
    Filed: April 5, 1993
    Date of Patent: September 6, 1994
    Assignee: Elf Sanofi
    Inventor: Henri Desmolin
  • Pharmaceutical composition based on valproic acid and a process for preparing it
    Patent number: 5185159
    Abstract: New pharmaceutical composition based on valproic acid and one of the pharmaceutically acceptable salts thereof, obtained by a new galenic preparation process which makes it possible to improve and simplify the galenic production, this composition also containing excipients which favorably modify its kinetics and its bioavailability.
    Type: Grant
    Filed: February 12, 1991
    Date of Patent: February 9, 1993
    Assignee: Sanofi
    Inventors: Daniel Aubert, Francis Blanc, Henri Desmolin, Michel Morre, Lucette Sindely
  • Valproic acid preparations
    Patent number: 5017613
    Abstract: New pharmaceutical composition based on valproic acid and one of the pharmaceutically acceptable salts thereof, obtained by a new galenic preparation process which makes it possible to improve and simplify the galenic production, this composition also containing excipients which favorably modify its kinetics and its bioavailability.
    Type: Grant
    Filed: February 21, 1989
    Date of Patent: May 21, 1991
    Assignee: Sanofi, S. A.
    Inventors: Daniel Aubert, Francis Blanc, Henri Desmolin, Michel Morre, Lucette Sindely