Abstract: The cutting tool, for example a milling-cutter, with interchangeable insert-holding cartridges comprises a body (1) presenting a peripheral supporting face (4) directed towards the rear end of the body and recesses (2) distributed at its peripheral front end and intended to receive interchangeable cartridges (3). Each cartridge comprises at its front end a cutting bit (5), generally fixed in a removable manner, and a back portion (7) at its rear end presenting a supporting face (8) directed towards the front and intended to come, in a service position, in abutment against the supporting face (4) of the body. The fixing devices (9, 11) of the cartridges on the body of the tool are such that they enable an axial setting of the position of said cartridges, as well as the backward movement thereof for a temporary putting out of service.