Patents by Inventor Henri Vial

Henri Vial has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combination of a bis-thiazolium salt or a precursor thereof and artemisinin or a derivative thereof for treating acute malaria
    Patent number: 8304440
    Abstract: The present invention relates to a combination of antimalarial active ingredients, namely a bisthiazolium salt or a precursor thereof and artemisinin or derivatives thereof. The invention also relates to a pharmaceutical composition comprising such a combination and use thereof in the treatment and/or prevention of malaria.
    Type: Grant
    Filed: August 6, 2010
    Date of Patent: November 6, 2012
    Assignee: Sanofi
    Inventors: Laurent Fraisse, Henri Vial, Sharon Aurore Wein
  • Compounds with antiparasitic activity and medicines containing same
    Patent number: 8012985
    Abstract: The invention relates to compounds having an anti-parasitic, in particular antimalarial activity, characterized in that they correspond to general formula (I) Applications in particular as compounds with anti-parasitic activity.
    Type: Grant
    Filed: July 18, 2003
    Date of Patent: September 6, 2011
    Assignee: Centre National de la Recherche Scientifique (C.N.R.S.)
    Inventors: Henri Vial, Michele Calas, Roger Escale, Valerie Vidal, Francoise Bressolle, Marie-Laure Ancelin
  • COMBINATION OF A BIS-THIAZOLIUM SALT OR A PRECURSOR THEREOF AND ARTEMISININ OR A DERIVATIVE THEREOF FOR TREATING ACUTE MALARIA
    Publication number: 20110160254
    Abstract: The present invention relates to a combination of antimalarial active ingredients, namely a bisthiazolium salt or a precursor thereof and artemisinin or derivatives thereof. The invention also relates to a pharmaceutical composition comprising such a combination and use thereof in the treatment and/or prevention of malaria.
    Type: Application
    Filed: August 6, 2010
    Publication date: June 30, 2011
    Applicants: SANOFI-AVENTIS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQU (CNRS), UNIVERSITE MONTPELLIER II
    Inventors: Laurent FRAISSE, Henri VIAL, Sharon Aurore WEIN
  • Compounds with Antiparasitic Activity, Applications thereof to the Treatment of Infectious Diseases Caused by Apicomplexans
    Publication number: 20100292214
    Abstract: The Invention relates to compounds having an antiparasitic activity, and to their use as a drug, in particular as a drug for the prevention and/or treatment of parasitic diseases caused by apicomplexans. The invention also relates to pharmaceutical compositions containing those compounds.
    Type: Application
    Filed: June 2, 2008
    Publication date: November 18, 2010
    Applicants: commissariat a l'Energie Atomique, Centre National De La Recherche Scientifique
    Inventors: Michael Deligny, Nadia Saidani, Anne-Laure Bonneau, Cyrille Botte, Helene Hardre, Bernard Rousseau, Henri Vial, Corinne Mercier, Roman Lopez, Eric Marechal
  • Digalactolipidic Antigen Exposed on the Surface of Apicomplex Parasites, and Diagnostic and Therapeutic Use Thereof
    Publication number: 20100040615
    Abstract: The invention relates to a digalactolipidic antigen exposed on the surface of apicomplex parasites, in the form of a vegetable-type digalactoglycerolipid, and adapted for inducing the production of specific antibodies capable of inhibiting the proliferation and/or the invasive properties of said parasites; the invention also relates to a derived antibody or functional antibody fragment, and to their diagnostic, immunotherapeutic and vaccine applications in human beings or animals.
    Type: Application
    Filed: February 7, 2008
    Publication date: February 18, 2010
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE, CENTRE NATIONAL DE LA RECHERCHE SEIENTIFIQUE
    Inventors: Cyrille Botte, Nadia Saidani, Maryse Block, Jean-Francois Dubremetz, Henri Vial, Marie-France Cesbron-Delauw, Corinne Mercier, Eric Marechal
  • Quaternary bis-ammonium salt precursors and their uses as prodrugs having an antiparasitic activity
    Patent number: 6972343
    Abstract: The invention concerns drug precursors with antimalarial effect, characterised in that it consists in quaternary bis-ammonium salts of general formula (I) wherein A and A?, identical or different, are respectively either a group A1 and A?1 of formula (1) wherein n=2 to 4; R?1 is hydrogen, C1-C5 alkyl, optionally substituted by an aryl, a hydroxy, an alkoxy, wherein the alkyl comprises 1 to 5 C, or aryloxy and W is halogen or a nucleofuge group; or a group A2 which represents formyl-CHO, or acetyl-COCH3.
    Type: Grant
    Filed: July 21, 2000
    Date of Patent: December 6, 2005
    Assignee: CNRS
    Inventors: Henri Vial, Marie-Laure Ancelin, Valerie Vidal, Michele Calas, Jean-Jacques Bourguignon, Eric Rubi
  • Compounds with antiparasitic activity and medicines containing same
    Publication number: 20050176819
    Abstract: The invention relates to compounds having an anti-parasitic, in particular antimalarial activity, characterized in that they correspond to general formula (I) Applications in particular as compounds with anti-parasitic activity.
    Type: Application
    Filed: July 18, 2003
    Publication date: August 11, 2005
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.
    Inventors: Henri Vial, Michele Calas, Roger Escale, Valerie Vidal, Francoise Bressolle, Marie-Laure Ancelin
  • Antimalaria and antibabesiosis agents and pharmaceutical compositions containing such agents
    Patent number: 6096788
    Abstract: The invention concerns pharmaceutical compositions with antimalaria and antibabesiosis activity, the active substances of these compositions and their use for formulating antimalaria drugs.
    Type: Grant
    Filed: February 1, 1999
    Date of Patent: August 1, 2000
    Assignee: Virbac S.A.
    Inventors: Henri Vial, Michele Calas, Marie-Laure Ancelin, Louis Giral
  • Bis(2-aminopyridine)s, preparation method therefor and use thereof for controlling parasitic infections
    Patent number: 5834491
    Abstract: Substituted bis-2-aminopyridines of formula (1), wherein Q, R1,R2,R3,R4 are as defined in the specification. A method for preparing said compounds and the use thereof as a drug and in particular as active drugs for controlling parasiticc infections within red blood cells, e.g. malaria or babesiasis.
    Type: Grant
    Filed: July 2, 1997
    Date of Patent: November 10, 1998
    Assignee: Virbac
    Inventors: Henri Vial, Michele Calas, Jean-Jacques Bourguignon, Marie-Laure Ancelin, Louis Giral