Patents by Inventor Henricus Johannes Adam van der Poel

Henricus Johannes Adam van der Poel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STRATEGIES FOR HIGH THROUGHPUT IDENTIFICATION AND DETECTION OF POLYMORPHISMS
    Publication number: 20150232924
    Abstract: The invention relates to a method for the high throughput identification of single nucleotide polymorphisms by performing a complexity reduction on two or more samples to yield two or more libraries, sequencing at least part of the libraries, aligning the identified sequences and determining any putative single nucleotide polymorphisms, confirming any putative single nucleotide polymorphism, generating detection probes for the confirmed single nucleotide polymorphisms, subjection a test sample to the same complexity reduction to provide a test library and screen the test library for the presence or absence of the single nucleotide polymorphisms using the detection probe.
    Type: Application
    Filed: February 19, 2015
    Publication date: August 20, 2015
    Applicant: Keygene N.V.
    Inventors: Michael Josephus Theresia VAN EIJK, Henricus Johannes Adam Van der Poel
  • High throughput screening using combinatorial sequence barcodes
    Patent number: 9080210
    Abstract: The invention involves methods and uses of a combination of at least two nucleotide sequence identifiers in the preparation of a sample DNA for high throughput sequencing. Accordingly, in the high throughput sequencing a plurality of prepared sample DNAs, each preparation of a sample DNA comprises a unique combination of the at least two nucleotide sequence identifiers wherein a first nucleotide sequence identifier is selected from a group of nucleotide sequence identifiers and a second nucleotide sequence identifier is selected from the group of nucleotide sequence identifiers.
    Type: Grant
    Filed: June 8, 2011
    Date of Patent: July 14, 2015
    Assignee: Keygene N.V.
    Inventors: Michael Josephus Theresia Van Eijk, Henricus Johannes Adam Van Der Poel
  • Strategies for high throughput identification and detection of polymorphisms
    Patent number: 9023768
    Abstract: The invention relates to a method for the high throughput identification of single nucleotide polymorphisms by performing a complexity reduction on two or more samples to yield two or more libraries, sequencing at least part of the libraries, aligning the identified sequences and determining any putative single nucleotide polymorphisms, confirming any putative single nucleotide polymorphism, generating detection probes for the confirmed single nucleotide polymorphisms, subjection a test sample to the same complexity reduction to provide a test library and screen the test library for the presence or absence of the single nucleotide polymorphisms using the detection probe.
    Type: Grant
    Filed: April 15, 2014
    Date of Patent: May 5, 2015
    Assignee: Keygene N.V.
    Inventors: Michael Josephus Theresia Van Eijk, Henricus Johannes Adam Van Der Poel
  • STRATEGIES FOR HIGH THROUGHPUT IDENTIFICATION AND DETECTION OF POLYMORPHISMS
    Publication number: 20140274744
    Abstract: The invention relates to a method for the high throughput identification of single nucleotide polymorphisms by performing a complexity reduction on two or more samples to yield two or more libraries, sequencing at least part of the libraries, aligning the identified sequences and determining any putative single nucleotide polymorphisms, confirming any putative single nucleotide polymorphism, generating detection probes for the confirmed single nucleotide polymorphisms, subjection a test sample to the same complexity reduction to provide a test library and screen the test library for the presence or absence of the single nucleotide polymorphisms using the detection probe.
    Type: Application
    Filed: April 15, 2014
    Publication date: September 18, 2014
    Applicant: Keygene N.V.
    Inventors: Michael Josephus Theresia Van EIJK, Henricus Johannes Adam Van Der Poel
  • STRATEGIES FOR HIGH THROUGHPUT IDENTIFICATION AND DETECTION OF POLYMORPHISMS
    Publication number: 20140213462
    Abstract: The invention relates to a method for the high throughput identification of single nucleotide polymorphisms by performing a complexity reduction on two or more samples to yield two or more libraries, sequencing at least part of the libraries, aligning the identified sequences and determining any putative single nucleotide polymorphisms, confirming any putative single nucleotide polymorphism, generating detection probes for the confirmed single nucleotide polymorphisms, subjection a test sample to the same complexity reduction to provide a test library and screen the test library for the presence or absence of the single nucleotide polymorphisms using the detection probe.
    Type: Application
    Filed: January 28, 2014
    Publication date: July 31, 2014
    Applicant: Keygene N.V.
    Inventors: Michael Josephus Theresia VAN EIJK, Henricus Johannes Adam Van Der Poel
  • Strategies for high throughput identification and detection of polymorphisms
    Patent number: 8785353
    Abstract: The invention relates to a method for the high throughput identification of single nucleotide polymorphisms by performing a complexity reduction on two or more samples to yield two or more libraries, sequencing at least part of the libraries, aligning the identified sequences and determining any putative single nucleotide polymorphisms, confirming any putative single nucleotide polymorphism, generating detection probes for the confirmed single nucleotide polymorphisms, subjection a test sample to the same complexity reduction to provide a test library and screen the test library for the presence or absence of the single nucleotide polymorphisms using the detection probe.
    Type: Grant
    Filed: June 23, 2006
    Date of Patent: July 22, 2014
    Assignee: Keygene N.V.
    Inventors: Michael Josephus Theresia Van Eijk, Henricus Johannes Adam Van Der Poel
  • Strategies for high throughput identification and detection of polymorphisms
    Patent number: 8685889
    Abstract: The invention relates to a method for the high throughput identification of single nucleotide polymorphisms by performing a complexity reduction on two or more samples to yield two or more libraries, sequencing at least part of the libraries, aligning the identified sequences and determining any putative single nucleotide polymorphisms, confirming any putative single nucleotide polymorphism, generating detection probes for the confirmed single nucleotide polymorphisms, subjection a test sample to the same complexity reduction to provide a test library and screen the test library for the presence or absence of the single nucleotide polymorphisms using the detection probe.
    Type: Grant
    Filed: April 18, 2012
    Date of Patent: April 1, 2014
    Assignee: Keygene N.V.
    Inventors: Michael Josephus Theresia van Eijk, Henricus Johannes Adam van der Poel
  • COMBINATORIAL SEQUENCE BARCODES FOR HIGH THROUGHPUT SCREENING
    Publication number: 20130137587
    Abstract: The invention involves methods and uses of a combination of at least two nucleotide sequence identifiers in the preparation of a sample DNA for high throughput sequencing. Accordingly, in the high throughput sequencing a plurality of prepared sample DNAs, each preparation of a sample DNA comprises a unique combination of the at least two nucleotide sequence identifiers wherein a first nucleotide sequence identifier is selected from a group of nucleotide sequence identifiers and a second nucleotide sequence identifier is selected from the group of nucleotide sequence identifiers.
    Type: Application
    Filed: June 8, 2011
    Publication date: May 30, 2013
    Inventors: Michael Josephus Theresia Van Eijk, Henricus Johannes Adam Van Der Poel
  • STRATEGIES FOR HIGH THROUGHPUT IDENTIFICATION AND DETECTION OF POLYMORPHISMS
    Publication number: 20120316073
    Abstract: The invention relates to a method for the high throughput identification of single nucleotide polymorphisms by performing a complexity reduction on two or more samples to yield two or more libraries, sequencing at least part of the libraries, aligning the identified sequences and determining any putative single nucleotide polymorphisms, confirming any putative single nucleotide polymorphism, generating detection probes for the confirmed single nucleotide polymorphisms, subjection a test sample to the same complexity reduction to provide a test library and screen the test library for the presence or absence of the single nucleotide polymorphisms using the detection probe.
    Type: Application
    Filed: April 18, 2012
    Publication date: December 13, 2012
    Inventors: Michael Josephus Theresia van EIJK, Henricus Johannes Adam van der Poel
  • STRATEGIES FOR HIGH THROUGHPUT IDENTIFICATION AND DETECTION OF POLYMORPHISMS
    Publication number: 20090036323
    Abstract: The invention relates to a method for the high throughput identification of single nucleotide polymorphisms by performing a complexity reduction on two or more samples to yield two or more libraries, sequencing at least part of the libraries, aligning the identified sequences and determining any putative single nucleotide polymorphisms, confirming any putative single nucleotide polymorphism, generating detection probes for the confirmed single nucleotide polymorphisms, subjection a test sample to the same complexity reduction to provide a test library and screen the test library for the presence or absence of the single nucleotide polymorphisms using the detection probe.
    Type: Application
    Filed: June 23, 2006
    Publication date: February 5, 2009
    Applicant: Keygene N.V.
    Inventors: Michael Josephus Theresia van Eijk, Henricus Johannes Adam van der Poel