Patents by Inventor Henricus Leo Bernardus Maria Klaasen

Henricus Leo Bernardus Maria Klaasen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10456458
    Abstract: The present invention pertains to a composition containing an immunogenic cell preparation of killed Leptospira bacteria in an ethylenediaminetetraacetic acid solution. The invention also pertains to a vaccine to protect an animal against an infection with leptospira bacteria, wherein the vaccine comprises this composition. Also, the invention pertains to the use of ethylenediaminetetraacetic acid to stabilise an immunogenic preparation of killed Leptospira bacteria in a liquid carrier, by dissolving the ethylenediaminetetraacetic acid in the carrier.
    Type: Grant
    Filed: April 16, 2018
    Date of Patent: October 29, 2019
    Assignee: Intervet Inc.
    Inventors: Henricus Leo Bernardus Maria Klaasen, Eric Onno Rijke
  • Publication number: 20180228900
    Abstract: The present invention pertains to a composition containing an immunogenic cell preparation of killed Leptospira bacteria in an ethylenediaminetetraacetic acid solution. The invention also pertains to a vaccine to protect an animal against an infection with leptospira bacteria, wherein the vaccine comprises this composition. Also, the invention pertains to the use of ethylenediaminetetraacetic acid to stabilise an immunogenic preparation of killed Leptospira bacteria in a liquid carrier, by dissolving the ethylenediaminetetraacetic acid in the carrier.
    Type: Application
    Filed: April 16, 2018
    Publication date: August 16, 2018
    Applicant: Intervet Inc.
    Inventors: Henricus Leo Bernardus Maria Klaasen, Eric Onno Rijke
  • Patent number: 10016503
    Abstract: The present invention pertains to a composition containing an immunogenic cell preparation of killed Leptospira bacteria in an ethylenediaminetetraacetic acid solution. The invention also pertains to a vaccine to protect an animal against an infection with leptospira bacteria, wherein the vaccine comprises this composition. Also, the invention pertains to the use of ethylenediaminetetraacetic acid to stabilize an immunogenic preparation of killed Leptospira bacteria in a liquid carrier, by dissolving the ethylenediaminetetraacetic acid in the carrier.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: July 10, 2018
    Assignee: Intervet Inc.
    Inventors: Henricus Leo Bernardus Maria Klaasen, Eric Onno Rijke
  • Publication number: 20170021024
    Abstract: The present invention pertains to a composition containing an immunogenic cell preparation of killed Leptospira bacteria in an ethylenediaminetetraacetic acid solution. The invention also pertains to a vaccine to protect an animal against an infection with leptospira bacteria, wherein the vaccine comprises this composition. Also, the invention pertains to the use of ethylenediaminetetraacetic acid to stabilise an immunogenic preparation of killed Leptospira bacteria in a liquid carrier, by dissolving the ethylenediaminetetraacetic acid in the carrier.
    Type: Application
    Filed: October 7, 2016
    Publication date: January 26, 2017
    Applicant: Intervet Inc.
    Inventors: Henricus Leo Bernardus Maria Klaasen, Eric Onno Rijke
  • Patent number: 9480734
    Abstract: The present invention pertains to a composition containing an immunogenic cell preparation of killed Leptospira bacteria in an ethylenediaminetetraacetic acid solution. The invention also pertains to a vaccine to protect an animal against an infection with leptospira bacteria, wherein the vaccine comprises this composition. Also, the invention pertains to the use of ethylenediaminetetraacetic acid to stabilize an immunogenic preparation of killed Leptospira bacteria in a liquid carrier, by dissolving the ethylenediaminetetraacetic acid in the carrier.
    Type: Grant
    Filed: August 16, 2013
    Date of Patent: November 1, 2016
    Assignee: Intervet Inc.
    Inventors: Henricus Leo Bernardus Maria Klaasen, Eric Onno Rijke
  • Publication number: 20160213768
    Abstract: The present invention pertains to a vaccine directed against porcine pleuropneumonia, comprising lipopolysaccharide, wherein the vaccine comprises a polymyxin to reduce symptoms of an endotoxic shock arising from the lipopolysaccharide. The invention also pertains to a method to obtain such a vaccine and a method for administering the vaccine to a subject animal.
    Type: Application
    Filed: April 7, 2016
    Publication date: July 28, 2016
    Inventor: Henricus Leo Bernardus Maria Klaasen
  • Patent number: 9375480
    Abstract: The present invention pertains to a composition containing an immunogenic cell preparation of killed Leptospira bacteria in a citric acid solution. It also pertains to a vaccine to protect an animal against an infection with Leptospira bacteria, wherein the vaccine comprises this composition, and to the use of citric acid to stabilize an immunogenic preparation of killed Leptospira bacteria in a liquid carrier, by dissolving the citric acid in the carrier.
    Type: Grant
    Filed: August 16, 2013
    Date of Patent: June 28, 2016
    Assignee: Intervet Inc.
    Inventors: Henricus Leo Bernardus Maria Klaasen, Peter Loeffen, Eric Onno Rijke
  • Publication number: 20150231223
    Abstract: The present invention pertains to a composition containing an immunogenic cell preparation of killed Leptospira bacteria in an ethylenediaminetetraacetic acid solution. The invention also pertains to a vaccine to protect an animal against an infection with leptospira bacteria, wherein the vaccine comprises this composition. Also, the invention pertains to the use of ethylenediaminetetraacetic acid to stabilise an immunogenic preparation of killed Leptospira bacteria in a liquid carrier, by dissolving the ethylenediaminetetraacetic acid in the carrier.
    Type: Application
    Filed: August 16, 2013
    Publication date: August 20, 2015
    Inventors: Henricus Leo Bernardus Maria Klaasen, Eric Onno Rijke
  • Publication number: 20150216976
    Abstract: The present invention pertains to a composition containing an immunogenic cell preparation of killed Leptospira bacteria in a citric acid solution. It also pertains to a vaccine to protect an animal against an infection with Leptospira bacteria, wherein the vaccine comprises this composition, and to the use of citric acid to stabilise an immunogenic preparation of killed Leptospira bacteria in a liquid carrier, by dissolving the citric acid in the carrier.
    Type: Application
    Filed: August 16, 2013
    Publication date: August 6, 2015
    Inventors: Henricus Leo Bernardus Maria Klaasen, Peter Loeffen, Peter Rottier
  • Patent number: 8628766
    Abstract: The present invention pertains to the use of Streptococcus suis antigens corresponding to Streptococcus suis bacteria of a predetermined serotype in the manufacture of a vaccine for administration to a sow or gilt, to protect a piglet through the intake of colostrum of the said sow or gilt, against a disorder arising from Streptococcus suis bacteria of a serotype other than the predetermined one. The invention also pertains to Streptococcus suis antigens for use in the manufacture of such a vaccine.
    Type: Grant
    Filed: March 25, 2010
    Date of Patent: January 14, 2014
    Assignee: Intervet International B.V.
    Inventors: Henricus Leo Bernardus Maria Klaasen, Ruud Philip Antoon Maria Segers
  • Publication number: 20120128712
    Abstract: The present invention pertains to a vaccine directed against porcine pleuropneumonia, comprising lipopolysaccharide, wherein the vaccine comprises a polymyxin to reduce symptoms of an endotoxic shock arising from the lipopolysaccharide. The invention also pertains to a method to obtain such a vaccine and a method for administering the vaccine to a subject animal.
    Type: Application
    Filed: August 5, 2010
    Publication date: May 24, 2012
    Inventor: Henricus Leo Bernardus Maria Klaasen
  • Publication number: 20120021003
    Abstract: The present invention pertains to the use of Streptococcus suis antigens corresponding to Streptococcus suis bacteria of a predetermined serotype in the manufacture of a vaccine for administration to a sow or gilt, to protect a piglet through the intake of colostrum of the said sow or gilt, against a disorder arising from Streptococcus suis bacteria of a serotype other than the predetermined one. The invention also pertains to Streptococcus suis antigens for use in the manufacture of such a vaccine.
    Type: Application
    Filed: March 25, 2010
    Publication date: January 26, 2012
    Inventors: Henricus Leo Bernardus Maria Klaasen, Ruud Philip Antoon Maria Segers