Patents by Inventor Henricus Marie Janssen
Henricus Marie Janssen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150057237Abstract: The present invention relates to a modular supramolecular bioresorbable or biomedical material comprising (i) a polymer comprising at least two 4H-units and (ii) a biologically active compound. Optionally, the supramolecular bioresorbable or biomedical material comprises a bioresorbable or biomedical polymer as third component to tune its properties (mechanical and bioresorption properties). The supramolecular bioresorbable or biomedical material is especially suitable for biomedical applications such as controlled release of drugs, materials for tissue-engineering, materials for the manufacture of a prosthesis or an implant, medical imaging technologies.Type: ApplicationFiled: October 29, 2014Publication date: February 26, 2015Applicant: SupraPolix B.V.Inventors: Patricia Yvonne Wilhelmina DANKERS, Gaby Maria Leonarda HOORNE-VAN GEMERT, Henricus Marie JANSSEN, Egbert Willem MEIJER, Anton Willem BOSMAN
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Patent number: 8883188Abstract: The present invention relates to a modular supramolecular bioresorbable or biomedical material comprising (i) a polymer comprising at least two 4H-units and (ii) a biologically active compound. Optionally, the supramolecular bioresorbable or bio medical material comprises a bioresorbable or biomedical polymer as third component to tune its properties (mechanical and bioresorption properties). The supramolecular bioresorbable or biomedical material is especially suitable for biomedical applications such as controlled release of drugs, materials for tissue-engineering, materials for the manufacture of a prosthesis or an implant, medical imaging technologies.Type: GrantFiled: May 3, 2006Date of Patent: November 11, 2014Assignee: SupraPolix B.V.Inventors: Patricia Yvonne Wilhelmina Dankers, Gaby Maria Leonarda Hoorne-Van Gemert, Henricus Marie Janssen, Egbert Willem Meijer, Anton Willem Bosman
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Patent number: 8754213Abstract: The present invention relates to a supramolecular compound comprising a low molecular weight, apolar compound, said low molecular weight, apolar compound having a melting point of below 45° C., a molecular weight of about 80 to about 1500 amu and a HLB-value of lower than 8, said low molecular weight, apolar compound bearing a single 4H-unit per molecule. The supramolecular compound according to the present invention may be used in coating, ink, toner, resin, lacquer, adhesive or glue compositions.Type: GrantFiled: July 6, 2009Date of Patent: June 17, 2014Assignee: SupraPolix B.V.Inventors: Gaby Maria Leonarda Hoorne-van Gemert, Sandrine Chodorowski-Kimmès, Henricus Marie Janssen, Egbert Willem Meijer, Anton Willem Bosman
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Publication number: 20140142256Abstract: The present invention relates to a supramolecular polymer comprising 1-50 4H-units, said supramolecular polymer being obtainable by reacting at least one monomeric building block with a prepolymer. The present invention further relates to articles or compositions comprising the supramolecular polymer, in particular articles or compositions selected from the group consisting of decorative, thermo-reversible, or self-healing coatings, adhesive compositions, sealing compositions, thickeners, gelators and binders.Type: ApplicationFiled: October 18, 2013Publication date: May 22, 2014Applicant: SupraPolix B.V.Inventors: Gaby Maria Leonarda HOORNE-VAN GEMERT, Henricus Marie JANSSEN, Egbert Willem MEIJER, Anton Willem BOSMAN
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Publication number: 20140128482Abstract: The present invention relates to improved hydrogel materials using water gellants that are comprised of polymer backbones P to which hydrogen bonding 4H-units are covalently attached via a hydrophobic linker L. Optionally, the hydrogel contains additional ingredients or additives. These new reversible hydrogels can easily be fine-tuned in their mechanical performance and function and are especially suitable for biomedical applications.Type: ApplicationFiled: January 10, 2014Publication date: May 8, 2014Applicant: SupraPolix B.V.Inventors: Travis Wayne BAUGHMAN, Gaby Maria Leonarda Van Gemert, Henricus Marie Janssen, Egbert Willem Meijer, Anton Willem Bosman
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Patent number: 8628789Abstract: The present invention relates to improved hydrogel materials using water gellants that are comprised of polymer backbones P to which hydrogen bonding 4H-units are covalently attached via a hydrophobic linker L. Optionally, the hydrogel contains additional ingredients or additives. These new reversible hydrogels can easily be fine-tuned in their mechanical performance and function and are especially suitable for biomedical applications.Type: GrantFiled: March 21, 2008Date of Patent: January 14, 2014Assignee: SupraPolix, B.V.Inventors: Travis Wayne Baughman, Gaby Maria Leonarda Hoorne-Van Gemert, Henricus Marie Janssen, Egbert Willem Meijer, Anton Willem Bosman
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Publication number: 20130284601Abstract: A method of preparing an anion exchange membrane with anion exchange groups. The method includes polymerizing a first monomer with a functional group selected from the pyridine derivatives with a second monomer selected from the benzene derivatives, such as styrene, to form a copolymer. The copolymer may be crosslinked with a crosslinker. The functional group of the copolymer may be functionalized to an anion exchange group.Type: ApplicationFiled: March 20, 2013Publication date: October 31, 2013Applicant: VOLTEA B.V.Inventors: Albert Van Der Wal, Piotr Edward Dlugolecki, Hank Robert Reinhoudt, Michel Henri Chretien Joseph Van Houtem, Henricus Marie Janssen
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Publication number: 20130186761Abstract: An apparatus to remove ions, the apparatus including a housing, an inlet to let water into the housing, an outlet to let water out of the housing, a first electrode, a second electrode, a spacer between the first and second electrodes to allow water to flow between the first and second electrodes, and an ion exchange membrane between the first and/or second electrode and the spacer, wherein the membrane has a crosslinked hyperbranched polymer with ion exchange groups.Type: ApplicationFiled: September 16, 2011Publication date: July 25, 2013Applicant: VOLTEA B.V.Inventors: Albert Van Der Wal, Hank Robert Reinhoudt, Henricus Marie Janssen, Michel Henri Chretien Joseph Van Houtem
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Patent number: 8268952Abstract: The invention relates to supramolecular ionomers. i.e. polymers having quadruple hydrogen bonding units (4H-units) and ionic groups or ionogenic groups within their structure. The supramolecular ionomers can be dispersed or solubilized in water at high solids contents while maintaining low viscosities, facilitating easy use and processing of the resulting aqueous formulations. The aqueous supramolecular ionomer compositions have excellent film-forming properties. Moreover, the polymer materials have good mechanical properties after drying, as they are not tacky, show high elasticity and low or no creep.Type: GrantFiled: July 11, 2005Date of Patent: September 18, 2012Assignee: Suprapolix B.V.Inventors: Gaby Maria Leonarda Van Gemert, Ronny Mathieu Versteegen, Henricus Marie Janssen, Egbert Willem Meijer, Anton Willem Bosman
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Patent number: 8246990Abstract: The present invention relates to new hydrogel materials using water gellants that are comprised by hydrophilic polymers to which hydrogen bonding units are covalently attached. Optionally, the hydrogel contains additional ingredients or additives. These new reversible hydrogels can easily be fine-tuned in their mechanical performance and functionality and are especially suitable for cosmetic and biomedical applications.Type: GrantFiled: May 3, 2006Date of Patent: August 21, 2012Assignee: Suprapolix B.V.Inventors: Gaby Maria Leonarda Hoorne-Van Gemert, Henricus Marie Janssen, Egbert Willem Meijer, Anton Willem Bosman
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Publication number: 20120116014Abstract: The invention relates to a process for the preparation of a supramolecular polymer comprising 1-50 4H-units, in which a 4H building block is reacted with a prepolymer, wherein a 4H building block comprises a 4H-unit and a reactive group according to Formula (I): wherein 4H represents a 4H-unit, L represents a divalent, trivalent, tetravalent or pentavalent linking group, Fi represents a reactive group, and r is 1-4, is reacted with a pre-polymer comprising a complementary reactive group, wherein the reaction mixture comprising said 4H building block and said polymer comprises less than 10 wt. % of a non-reactive organic solvent, based on the total weight of the reaction mixture.Type: ApplicationFiled: November 4, 2011Publication date: May 10, 2012Inventors: Henricus Marie JANSSEN, Gaby Maria Leonarda VAN GEMERT, Anton Willem BOSMAN
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Publication number: 20100298403Abstract: The present invention is concerned with modified poly-(propylene imine) dendrimers, comprising cationic internal ammonium groups and external non-toxic endgroups, pharmaceutical compositions comprising said dendrimers, methods for the production of said dendrimers and their use as transfections agents for anionic bioactive therapeutic factors, for use in gene therapy, in particular for the treatment of cancer. The modified poly-(propylene imine) dendrimer of generation 1, 2, 3, 4 or 5, also comprising incomplete dendrimers and mixtures thereof, comprising external end groups and internal amine functions are characterized in that: (a) substantially all external endgroups are groups of formula (I) ?wherein R is a radical selected from the group of C1-10alkyl, polyethylene glycol radical and polyethylene glycol gallyl radical; and (b) substantially all internal amine functions are quaternary cationic ammonium functions.Type: ApplicationFiled: July 5, 2006Publication date: November 25, 2010Applicant: JANSSEN PHARMACEUTICA N.V.Inventors: Frederik Tack, Henricus Marie Janssen, Egbert Willem Meijer, Michel Marie Francois Janicot, Marcus Eli Brewster
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Publication number: 20100076147Abstract: PCT The present invention relates to a supramolecular polymer comprising 1-50 4H-units, said supramolecular polymer being obtainable by reacting at least one monomeric building block with a prepolymer. The present invention further relates to articles or compositions comprising the supramolecular polymer, in particular articles or compositions selected from the group consisting of decorative, thermo-reversible, or self-healing coatings, adhesive compositions, sealing compositions, thickeners, gelators and binders.Type: ApplicationFiled: November 14, 2007Publication date: March 25, 2010Applicant: SUPRAPOLIX B.V.Inventors: Gaby Maria Leonarda Hoorne-Van Gemert, Henricus Marie Janssen, Egbert Willem Meijer, Anton Willem Bosman
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Publication number: 20090130172Abstract: The present invention relates to a modular supramolecular bioresorbable or biomedical material comprising (i) a polymer comprising at least two 4H-units and (ii) a biologically active compound. Optionally, the supramolecular bioresorbable or bio medical material comprises a bioresorbable or biomedical polymer as third component to tune its properties (mechanical and bioresorption properties). The supramolecular bioresorbable or biomedical material is especially suitable for biomedical applications such as controlled release of drugs, materials for tissue-engineering, materials for the manufacture of a prosthesis or an implant, medical imaging technologies.Type: ApplicationFiled: May 3, 2006Publication date: May 21, 2009Inventors: Patricia Yvonne Wilhelmina Dankers, Gaby Maria Hoorne-Van Gemert, Henricus Marie Janssen, Egbert Willem Meijer, Anton Willem Bosman
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Publication number: 20090111930Abstract: The invention relates to supramolecular ionomers. i.e. polymers having quadruple hydrogen bonding units (4H-units) and ionic groups or ionogenic groups within their structure. The supramolecular ionomers can be dispersed or solubilized in water at high solids contents while maintaining low viscosities, facilitating easy use and processing of the resulting aqueous formulations. The aqueous supramolecular ionomer compositions have excellent film-forming properties. Moreover, the polymer materials have good mechanical properties after drying, as they are not tacky, show high elasticity and low or no creep.Type: ApplicationFiled: July 11, 2005Publication date: April 30, 2009Inventors: Gaby Maria Leonarda van Gemert, Ronny Mathieu Versteegen, Henricus Marie Janssen, Egbert Willem Meijer, Anton Willem Bosman
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Publication number: 20090004274Abstract: The present invention relates to new hydrogel materials using water gellants that are comprised by hydrophilic polymers to which hydrogen bonding units are covalently attached. Optionally, the hydrogel contains additional ingredients or additives. These new reversible hydrogels can easily be fine-tuned in their mechanical performance and functionality and are especially suitable for cosmetic and biomedical applications.Type: ApplicationFiled: May 3, 2006Publication date: January 1, 2009Applicant: SUPRAPOLIX B.V.Inventors: Gaby Maria Hoorne-Van Gemert, Henricus Marie Janssen, Egbert Willem Meijer, Anton Willem Bosman
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Publication number: 20080260795Abstract: The present invention relates to improved hydrogel materials using water gellants that are comprised of polymer backbones P to which hydrogen bonding 4H-units are covalently attached via a hydrophobic linker L. Optionally, the hydrogel contains additional ingredients or additives. These new reversible hydrogels can easily be fine-tuned in their mechanical performance and function and are especially suitable for biomedical applications.Type: ApplicationFiled: March 21, 2008Publication date: October 23, 2008Inventors: Trayvis Wayne BAUGHMAN, Gaby Maria Leonarda Hoorne - van Gemert, Henricus Marie JANSSEN, Egbert Willem MEIJER, Anton Willem Bosman
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Patent number: 6803447Abstract: The invention relates to the synthesis of polymers containing self-complementary quadruple hydrogen groups by copolymerizing monomers containing a quadruple hydrogen bonding group with one or more monomers of choice. The resulting polymers show unique new characteristics due to the presence of additional physical interactions between the polymer chains that are based on multiple hydrogen bonding interactions (supramolecular interactions).Type: GrantFiled: August 21, 2002Date of Patent: October 12, 2004Assignee: Eutechpark MMP1.28Inventors: Henricus Marie Janssen, Gaby Maria Leonarda Van Gemert, Aafke Tessa Ten Cate, Dimphna Johanna Maria Van Beek, Rintje Pieter Sijbesma, Egbert Willem Meijer, Anton Willem Bosman
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Publication number: 20040034190Abstract: The invention relates to the synthesis of polymers containing self-complementary quadruple hydrogen groups by copolymerizing monomers containing a quadruple hydrogen bonding group with one or more monomers of choice. The resulting polymers show unique new characteristics due to the presence of additional physical interactions between the polymer chains that are based on multiple hydrogen bonding interactions (supramolecular interactions).Type: ApplicationFiled: August 21, 2002Publication date: February 19, 2004Inventors: Henricus Marie Janssen, Gaby Maria Leonarda Van Gemert, Aafke Tessa Ten Cate, Dimphna Johanna Maria Van Beek, Rintje Pieter Sijbesma, Egbert Willem Meijer, Anton Willem Bosman