Patents by Inventor Henricus P. C. Hogenkamp

Henricus P. C. Hogenkamp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cobalamin conjugates useful as imaging and therapeutic agents
    Patent number: 7591995
    Abstract: The invention provides detectably labeled cobalamin derivatives which are useful for medical treatment and diagnosis.
    Type: Grant
    Filed: October 31, 2006
    Date of Patent: September 22, 2009
    Assignees: Mayo Foundation for Medical Education and Research, Regents of the University of Minnesota
    Inventors: Douglas A. Collins, Henricus P. C. Hogenkamp
  • Radionuclide labeling of Vitamin B12 and Co-enzymes thereof
    Publication number: 20090162281
    Abstract: A compound useful for in vivo imaging of organs and tumors is provided of formula: wherein is a cobalamin, is derived from a corrin carboxylic acid group of said cobalamin, Y is a linking group and X is a chelating group, optionally comprising a detectable radionuclide or a paramagnetic metal ion, and n is 1-3.
    Type: Application
    Filed: November 4, 2008
    Publication date: June 25, 2009
    Inventors: Douglas A. Collins, Henricus P. C. Hogenkamp
  • Transcobalamin receptor binding conjugates useful for treating abnormal cellular proliferation
    Patent number: 7531162
    Abstract: An agent, composition and method for the treatment, prophylaxis and/or diagnosis of proliferative disorders, which is highly and efficiently absorbed at the site of abnormal cellular proliferation is disclosed.
    Type: Grant
    Filed: February 13, 2006
    Date of Patent: May 12, 2009
    Assignees: Mayo Foundation for Medical Education and Research, Regents of the University of Minnesota
    Inventors: Douglas A. Collins, Henricus P. C. Hogenkamp
  • Cobalamin conjugates useful as antitumor agents
    Patent number: 7468432
    Abstract: The invention provides cobalamin compounds linked to a neutron capture therapy target (e.g. Boron-10 or Gadolinium-157), and optionally linked to a detectable moiety, as well as pharmaceutical compositions comprising the compounds, and methods for using the compounds in medical diagnosis and therapy.
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: December 23, 2008
    Assignees: Mayo Foundation for Medical Education and Research, Regents of the University of Minnesota
    Inventors: Douglas A. Collins, Henricus P. C. Hogenkamp
  • Cobalamin conjugates useful as imaging and therapeutic agents
    Patent number: 7179445
    Abstract: The invention provides detectably labeled cobalamin derivatives which are useful for medical treatment and diagnosis.
    Type: Grant
    Filed: February 24, 2004
    Date of Patent: February 20, 2007
    Assignees: Mayo Foundation for Medical Education and Research, Regents of the University of Minnesota
    Inventors: Douglas A. Collins, Henricus P. C. Hogenkamp
  • Cobalamin conjugates useful as imaging and therapeutic agents
    Patent number: 6838073
    Abstract: The invention provides detectably labeled cobalamin derivatives which are useful for medical treatment and diagnosis.
    Type: Grant
    Filed: October 16, 2000
    Date of Patent: January 4, 2005
    Assignees: Mayo Foundation for Medical Education and Research, Regents of the University of Minnesota
    Inventors: Douglas A. Collins, Henricus P. C. Hogenkamp
  • Cobalamin conjugates useful as antitumor agents
    Patent number: 6806363
    Abstract: The invention provides cobalamin compounds linked to a neutron capture therapy target (e.g. Boron-10 or Gadolinium-157), and optionally linked to a detectable moiety, as well as pharmaceutical compositions comprising the compounds, and methods for using the compounds in medical diagnosis and therapy.
    Type: Grant
    Filed: October 16, 2000
    Date of Patent: October 19, 2004
    Assignees: Mayo Foundation for Medical Education & Research, Minnesota, Regents of the University
    Inventors: Douglas A. Collins, Henricus P. C. Hogenkamp
  • Cobalamin conjugates useful as imaging and therapeutic agents
    Publication number: 20040166059
    Abstract: The invention provides detectably labeled cobalamin derivatives which are useful for medical treatment and diagnosis.
    Type: Application
    Filed: February 24, 2004
    Publication date: August 26, 2004
    Applicants: Mayo Foundation for Medical Education and Research, Regents of the University of Minnesota
    Inventors: Douglas A. Collins, Henricus P.C. Hogenkamp
  • Cobalamin conjugates useful as antitumor agents
    Publication number: 20040162240
    Abstract: The invention provides cobalamin compounds linked to a neutron capture therapy target (e.g. Boron-10 or Gadolinium-157), and optionally linked to a detectable moiety, as well as pharmaceutical compositions comprising the compounds, and methods for using the compounds in medical diagnosis and therapy.
    Type: Application
    Filed: February 12, 2004
    Publication date: August 19, 2004
    Applicants: Mayo Foundation for Medical Education and Research, Regents of the University of Minnesota
    Inventors: Douglas A. Collins, Henricus P.C. Hogenkamp
  • Transcobalamin receptor binding conjugates useful for treating abnormal cellular proliferation
    Publication number: 20020151525
    Abstract: An agent, composition and method for the treatment, prophylaxis and/or diagnosis of proliferative disorders, which is highly and efficiently absorbed at the site of abnormal cellular proliferation is disclosed.
    Type: Application
    Filed: October 25, 2001
    Publication date: October 17, 2002
    Inventors: Douglas A. Collins, Henricus P.C. Hogenkamp
  • Cobalamin compounds useful as cardiovascular agents and as imaging agents
    Publication number: 20020049155
    Abstract: The invention provides cobalamin derivatives linked to a cardiovascular agent, as well as pharmaceutical compositions comprising the compounds and methods for using the compounds in treatment or diagnosis of a cardiovascular disease.
    Type: Application
    Filed: May 31, 2001
    Publication date: April 25, 2002
    Inventor: Henricus P.C. Hogenkamp
  • Cobalamin compounds useful as antibiotic agents and as imaging agents
    Publication number: 20020042394
    Abstract: The invention provides cobalamin derivatives linked to an antibiotic and/or an imaging agent, as well as pharmaceutical compositions comprising the compounds and methods for using the compounds in treatment or diagnosis of a microbial infection.
    Type: Application
    Filed: May 31, 2001
    Publication date: April 11, 2002
    Inventors: Henricus P.C. Hogenkamp, Douglas A. Collins