Patents by Inventor Henricus Willem M. De Bruyn

Henricus Willem M. De Bruyn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8175695
    Abstract: A method and system for detecting T-wave alternans for use in an implanted medical device uses wave transformation of QT intervals to obtain a reliable measure of TWA. In one embodiment, an array provides alternating sign multiplication factors which are applied respectively to n consecutive QT values. Each successive QT value is high pass filtered and moved sequentially through a queue so that each cycle each of the n QT values is multiplied by one of the factors; the products are summed and made absolute to provide an alternans match value. The alternans match is compared with a noise threshold signal, and alternans is declared when the match exceeds the threshold by a predetermined amount. The array is programmable and can be varied, providing a high degree of flexibility to optimize the test for the patient.
    Type: Grant
    Filed: February 18, 2010
    Date of Patent: May 8, 2012
    Assignee: Medtronic, Inc.
    Inventors: Mattias Rouw, Christianus J. J. E. Van Groeningen, Henricus Willem M. De Bruyn
  • Publication number: 20100145404
    Abstract: A method and system for detecting T-wave alternans for use in an implanted medical device uses wave transformation of QT intervals to obtain a reliable measure of TWA. In one embodiment, an array provides alternating sign multiplication factors which are applied respectively to n consecutive QT values. Each successive QT value is high pass filtered and moved sequentially through a queue so that each cycle each of the n QT values is multiplied by one of the factors; the products are summed and made absolute to provide an alternans match value. The alternans match is compared with a noise threshold signal, and alternans is declared when the match exceeds the threshold by a predetermined amount. The array is programmable and can be varied, providing a high degree of flexibility to optimize the test for the patient.
    Type: Application
    Filed: February 18, 2010
    Publication date: June 10, 2010
    Applicant: Medtronic, Inc.
    Inventors: Mattias Rouw, Christianus J.J.E. Van Groeningen, Henricus Willem M. De Bruyn
  • Patent number: 7725172
    Abstract: A method and system for detecting T-wave alternans for use in an implanted medical device uses wave transformation of QT intervals to obtain a reliable measure of TWA. In one embodiment, an array provides alternating sign multiplication factors which are applied respectively to n consecutive QT values. Each successive QT value is high pass filtered and moved sequentially through a queue so that each cycle each of the n QT values is multiplied by one of the factors; the products are summed and made absolute to provide an alternans match value. The alternans match is compared with a noise threshold signal, and alternans is declared when the match exceeds the threshold by a predetermined amount. The array is programmable and can be varied, providing a high degree of flexibility to optimize the test for the patient.
    Type: Grant
    Filed: January 12, 2004
    Date of Patent: May 25, 2010
    Assignee: Medtronic, Inc.
    Inventors: Mattias Rouw, Christianus J. J. E. Van Groeningen, Henricus Willem M. De Bruyn
  • Publication number: 20040186527
    Abstract: A method and system for detecting T-wave alternans for use in an implanted medical device uses wave transformation of QT intervals to obtain a reliable measure of TWA. In one embodiment, an array provides alternating sign multiplication factors which are applied respectively to n consecutive QT values. Each successive QT value is high pass filtered and moved sequentially through a queue so that each cycle each of the n QT values is multiplied by one of the factors; the products are summed and made absolute to provide an alternans match value. The alternans match is compared with a noise threshold signal, and alternans is declared when the match exceeds the threshold by a predetermined amount. The array is programmable and can be varied, providing a high degree of flexibility to optimize the test for the patient.
    Type: Application
    Filed: January 12, 2004
    Publication date: September 23, 2004
    Inventors: Mattias Rouw, Christianus J.J.E. Van Groeningen, Henricus Willem. M. De Bruyn